Search Results - "Prasad, Shikha"

NRF2 and NF-қB interplay in cerebrovascular and neurodegenerative disorders: Molecular mechanisms and possible therapeutic approaches by Sivandzade, Farzane, Prasad, Shikha, Bhalerao, Aditya, Cucullo, Luca

“…Electrophiles and reactive oxygen species (ROS) play a major role in modulating cellular defense mechanisms as well as physiological functions, and…”
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Antineutrino detection for temporal monitoring of fuel burnup in a large nuclear reactor by Ang, Wei Eng, Prasad, Shikha, Chirayath, Sunil S.

“…The objective of this work is to determine if coherent-elastic-neutrino-nucleus scatter (CEνNS) in natural germanium detectors can be used to detect…”
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Role of Nrf2 and protective effects of Metformin against tobacco smoke-induced cerebrovascular toxicity by Prasad, Shikha, Sajja, Ravi K, Kaisar, Mohammad Abul, Park, Jee Hyun, Villalba, Heidi, Liles, Taylor, Abbruscato, Thomas, Cucullo, Luca

“…Cigarette smoking (CS) is associated with vascular endothelial dysfunction in a causative way primarily related to the TS content of reactive oxygen species…”
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Importance of self-shielding in mass measurements using γ-ray spectroscopy by Norris, Jesse D, Prasad, Shikha

“…Due to the exponential attenuation of photons in materials, thick samples will attenuate a large portion of photons. This is a source of error in methods such…”
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New experimental models of the blood-brain barrier for CNS drug discovery by Kaisar, Mohammad A, Sajja, Ravi K, Prasad, Shikha, Abhyankar, Vinay V, Liles, Taylor, Cucullo, Luca

“…The blood-brain barrier (BBB) is a dynamic biological interface which actively controls the passage of substances between the blood and the central nervous…”
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Offsetting the impact of smoking and e-cigarette vaping on the cerebrovascular system and stroke injury: Is Metformin a viable countermeasure? by Kaisar, Mohammad A., Villalba, Heidi, Prasad, Shikha, Liles, Taylor, Sifat, Ali Ehsan, Sajja, Ravi K., Abbruscato, Thomas J., Cucullo, Luca

“…Recently published in vitro and in vivo findings strongly suggest that BBB impairment and increased risk for stroke by tobacco smoke (TS) closely resemble that…”
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Impact of altered glycaemia on blood-brain barrier endothelium: an in vitro study using the hCMEC/D3 cell line by Sajja, Ravi K, Prasad, Shikha, Cucullo, Luca

“…Cerebrovascular complications involving endothelial dysfunction at the blood-brain barrier (BBB) are central to the pathogenesis of diabetes-related CNS…”
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Unhealthy smokers: scopes for prophylactic intervention and clinical treatment by Prasad, Shikha, Kaisar, Mohammad Abul, Cucullo, Luca

“…Globally, tobacco use causes approximately 6 million deaths per year, and predictions report that with current trends; more than 8 million deaths are expected…”
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Targeting Pioneering Factor and Hormone Receptor Cooperative Pathways to Suppress Tumor Progression by SHAH, Supriya, PRASAD, Shikha, KNUDSEN, Karen E

“…Nuclear receptors and pioneer factors drive the development and progression of prostate cancer. In this disease, aggressive disease phenotypes and hormone…”
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Impact of cigarette smoke extract and hyperglycemic conditions on blood-brain barrier endothelial cells by Prasad, Shikha, Sajja, Ravi K, Park, Jee Hyun, Naik, Pooja, Kaisar, Mohammad Abul, Cucullo, Luca

“…Diabetes and tobacco smoking are significant public health concerns which have been shown to independently impact the blood-brain barrier (BBB). Since smoking…”
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Neutron spectrum reconstruction for liquid organic scintillators in low information scenarios via genetic algorithm by Halvic, Ian, Prasad, Shikha

“…Construction of neutron energy spectrum is of interest in various scientific fields such as nuclear power, nuclear security, industrial applications of nuclear…”
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A Decade of e-Cigarettes: Limited Research & Unresolved Safety Concerns by Kaisar, Mohammad Abul, Prasad, Shikha, Liles, Tylor, Cucullo, Luca

“…Abstract It is well known that tobacco consumption is a leading cause of preventable deaths worldwide and has been linked to major diseases ranging from cancer…”
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Coherent elastic neutrino nucleus scatter response of semiconductor detectors to nuclear reactor antineutrinos by Ang, Wei Eng, Prasad, Shikha, Mahapatra, Rupak

“…We studied the performance of advanced semiconductor detectors to measure reactor antineutrino with the potential to drastically improve efficiency and lower…”
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Protecting the BBB endothelium against cigarette smoke-induced oxidative stress using popular antioxidants: Are they really beneficial? by Kaisar, Mohammad Abul, Prasad, Shikha, Cucullo, Luca

“…Abstract Blood Brain Barrier (BBB) exposed to realistic concentrations (comparable to a chronic heavy smoker) of Cigarette Smoke Extract (CSE) triggers a…”
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Effect of tree species and seasons on soil nitrogen transformation rates in the semi-arid forest of Delhi, India by Prasad, Shikha, Baishya, Ratul

“…Soil nitrogen mineralization (N min) is a very crucial component of N cycling. By far, studies have primarily shown the effect of seasons on N min. However,…”
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Pericytes and Astrocytes Crosstalk: Understanding Perivascular Synergism at the BBB by Prasad, Shikha, Cucullo, Luca

“…Abstract only The Blood brain barrier (BBB) plays a critical role in maintaining brain homeostasis. Astrocytes (AC) lying adjacent to BBB endothelial cells…”
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Blood-brain barrier disruption in diabetic mice is linked to Nrf2 signaling deficits: Role of ABCB10? by Sajja, Ravi K., Prasad, Shikha, Tang, Suni, Kaisar, Mohammad A., Cucullo, Luca

“…•In vivo fluorescence imaging revealed BBB hyper-permeability in diabetic mice.•Nrf2 is significantly down-regulated in diabetic brain.•Nrf2 regulates…”
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Isotopic characterization and thermal neutron flux determination of a PuBe neutron source by Purty, Ravi Ankit, Akanchha, Prasad, Shikha

“…The Indian Institute of Technology Kanpur (IIT Kanpur) possesses a PuBe neutron source facility with an initial activity of 5 Ci, dated September 1966 (nearly…”
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Oxidative and pro-inflammatory impact of regular and denicotinized cigarettes on blood brain barrier endothelial cells: is smoking reduced or nicotine-free products really safe? by Naik, Pooja, Fofaria, Neel, Prasad, Shikha, Sajja, Ravi K, Weksler, Babette, Couraud, Pierre-Olivier, Romero, Ignacio A, Cucullo, Luca

“…Both active and passive tobacco smoke (TS) potentially impair the vascular endothelial function in a causative and dose-dependent manner, largely related to…”
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Vorinostat Induces Blood‐Brain Barrier P‐Glycoprotein Drug Efflux Activity: Implications for Limited Brain Disposition of Co‐administered Chemotherapeutics by Sajja, Ravi Kiran, Liles, Taylor R, Prasad, Shikha, Cucullo, Luca

“…Abstract only…”
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