Search Results - "Prasad, Mahadesh"

Transcription factor networks in B-cell differentiation link development to acute lymphoid leukemia by Somasundaram, Rajesh, Prasad, MahadeshA.J., Ungerbäck, Jonas, Sigvardsson, Mikael

“…B-lymphocyte development in the bone marrow is controlled by the coordinated action of transcription factors creating regulatory networks ensuring activation…”
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H2AX Phosphorylation Is Important for LANA-Mediated Kaposi's Sarcoma-Associated Herpesvirus Episome Persistence by Jha, Hem Chandra, Upadhyay, Santosh Kumar, A J Prasad, Mahadesh, Lu, Jie, Cai, Qiliang, Saha, Abhik, Robertson, Erle S

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A single-dose live-attenuated YF17D-vectored SARS-CoV-2 vaccine candidate by Sanchez-Felipe, Lorena, Vercruysse, Thomas, Sharma, Sapna, Ma, Ji, Lemmens, Viktor, Van Looveren, Dominique, Arkalagud Javarappa, Mahadesh Prasad, Boudewijns, Robbert, Malengier-Devlies, Bert, Liesenborghs, Laurens, Kaptein, Suzanne J. F., De Keyzer, Carolien, Bervoets, Lindsey, Debaveye, Sarah, Rasulova, Madina, Seldeslachts, Laura, Li, Li-Hsin, Jansen, Sander, Yakass, Michael Bright, Verstrepen, Babs E., Böszörményi, Kinga P., Kiemenyi-Kayere, Gwendoline, van Driel, Nikki, Quaye, Osbourne, Zhang, Xin, ter Horst, Sebastiaan, Mishra, Niraj, Deboutte, Ward, Matthijnssens, Jelle, Coelmont, Lotte, Vandermeulen, Corinne, Heylen, Elisabeth, Vergote, Valentijn, Schols, Dominique, Wang, Zhongde, Bogers, Willy, Kuiken, Thijs, Verschoor, Ernst, Cawthorne, Christopher, Van Laere, Koen, Opdenakker, Ghislain, Vande Velde, Greetje, Weynand, Birgit, Teuwen, Dirk E., Matthys, Patrick, Neyts, Johan, Jan Thibaut, Hendrik, Dallmeier, Kai

“…The expanding pandemic of coronavirus disease 2019 (COVID-19) requires the development of safe, efficacious and fast-acting vaccines. Several vaccine platforms…”
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Epstein-Barr virus essential antigen EBNA3C attenuates H2AX expression by Jha, Hem C, A J, Mahadesh Prasad, Saha, Abhik, Banerjee, Shuvomoy, Lu, Jie, Robertson, Erle S

“…Epstein-Barr virus (EBV) latent antigen EBNA3C is implicated in B-cell immortalization and linked to several B-cell malignancies. Deregulation of H2AX can…”
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EBNA3C-Mediated Regulation of Aurora Kinase B Contributes to Epstein-Barr Virus-Induced B-Cell Proliferation through Modulation of the Activities of the Retinoblastoma Protein and Apoptotic Caspases by Jha, Hem Chandra, Lu, Jie, Saha, Abhik, Cai, Qiliang, Banerjee, Shuvomoy, Prasad, Mahadesh A J, Robertson, Erle S

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EBF1 and PAX5 control pro-B cell expansion via opposing regulation of the Myc gene by Somasundaram, Rajesh, Jensen, Christina T., Tingvall-Gustafsson, Johanna, Åhsberg, Josefine, Okuyama, Kazuki, Prasad, Mahadesh, Hagman, James R., Wang, Xun, Soneji, Shamit, Strid, Tobias, Ungerbäck, Jonas, Sigvardsson, Mikael

“…Genes encoding B lineage–restricted transcription factors are frequently mutated in B-lymphoid leukemias, suggesting a close link between normal and malignant…”
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PAX5 is part of a functional transcription factor network targeted in lymphoid leukemia by Okuyama, Kazuki, Strid, Tobias, Kuruvilla, Jacob, Somasundaram, Rajesh, Cristobal, Susana, Smith, Emma, Prasad, Mahadesh, Fioretos, Thoas, Lilljebjörn, Henrik, Soneji, Shamit, Lang, Stefan, Ungerbäck, Jonas, Sigvardsson, Mikael

“…One of the most frequently mutated proteins in human B-lineage leukemia is the transcription factor PAX5. These mutations often result in partial rather than…”
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E2F1 mediated apoptosis induced by the DNA damage response is blocked by EBV nuclear antigen 3C in lymphoblastoid cells by Saha, Abhik, Lu, Jie, Morizur, Lise, Upadhyay, Santosh K, Aj, Mahadesh Prasad, Robertson, Erle S

“…EBV latent antigen EBNA3C is indispensible for in vitro B-cell immortalization resulting in continuously proliferating lymphoblastoid cell lines (LCLs). EBNA3C…”
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Ebf1 heterozygosity results in increased DNA damage in pro-B cells and their synergistic transformation by Pax5 haploinsufficiency by Prasad, Mahadesh.A.J., Ungerbäck, Jonas, Åhsberg, Josefine, Somasundaram, Rajesh, Strid, Tobias, Larsson, Malin, Månsson, Robert, De Paepe, Ayla, Lilljebjörn, Henrik, Fioretos, Thoas, Hagman, James, Sigvardsson, Mikael

“…Early B-cell factor 1 (Ebf1) is a transcription factor with documented dose-dependent functions in normal and malignant B-lymphocyte development. To understand…”
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B Lymphocyte Specification Is Preceded by Extensive Epigenetic Priming in Multipotent Progenitors by Strid, Tobias, Okuyama, Kazuki, Tingvall-Gustafsson, Johanna, Kuruvilla, Jacob, Jensen, Christina T., Lang, Stefan, Prasad, Mahadesh, Somasundaram, Rajesh, Åhsberg, Josefine, Cristobal, Susana, Soneji, Shamit, Ungerbäck, Jonas, Sigvardsson, Mikael

“…B lymphocyte development is dependent on the interplay between the chromatin landscape and lineage-specific transcription factors. It has been suggested that B…”
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Bioactivity of diterpens from the ethyl acetate extract of Kingiodendron pinnatum rox. hams by Javarappa, Komal, Prasad, Attemode, Mahadesh Prasad, A, Mane, Chetana

“…Background: Kingiodendron pinnatum Rox. Hams. is an endangered medicinal plant used in gonorrhoe, catarrhal conditions of genito-urinary and respiratory…”
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Live-attenuated YF17D-vectored COVID-19 vaccine protects from lethal yellow fever virus infection in mouse and hamster models by Ma, Ji, Yakass, Michael Bright, Jansen, Sander, Malengier-Devlies, Bert, Van Looveren, Dominique, Sanchez-Felipe, Lorena, Vercruysse, Thomas, Weynand, Birgit, Javarappa, Mahadesh Prasad Arkalagud, Quaye, Osbourne, Matthys, Patrick, Roskams, Tania, Neyts, Johan, Thibaut, Hendrik Jan, Dallmeier, Kai

“…The live-attenuated yellow fever vaccine YF17D holds great promise as alternative viral vector vaccine platform, showcased by our previously presented potent…”
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Dissecting the contribution of EBNA3C domains important for EBV-induced B-cell growth and proliferation by Jha, Hem Chandra, Shukla, Sanket Kumar, Lu, Jie, Aj, Mahadesh Prasad, Banerjee, Shuvomoy, Robertson, Erle S

“…Epstein-Barr virus (EBV) is an oncogenic gammaherpes virus which is linked to pathogenesis of several human lymphatic malignancies. The EBV essential latent…”
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Effective paclitaxel: β -Cyclodextrin-based formulation boosts in vitro anti-tumor potential and lowers toxicity in zebrafish by Show, Sautan, Dutta, Debanjan, Nongthomba, Upendra, Prasad A J, Mahadesh

“…Paclitaxel (PCTX) is one of the most prevalently used chemotherapeutic agents. However, its use is currently beset with a host of problems: solubility issue,…”
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Cassia tora prevents Aβ 1-42 aggregation, inhibits acetylcholinesterase activity and protects against Aβ 1-42 -induced cell death and oxidative stress in human neuroblastoma cells by Ravi, Sunil K, Narasingappa, Ramesh B, Prasad, Mahadesh, Javagal, Manjunath R, Vincent, Bruno

“…Alzheimer's is a complex neurodegenerative disease and is characterized by extraneuronal accumulation of β-amyloid peptide. Because of its complex nature,…”
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The association of cysteine to thiomersal attenuates its apoptosis-mediated cytotoxicity in zebrafish by Dutta, Debanjan, Show, Sautan, Pal, Anabadya, Anifowoshe, Abass Toba, Prasad Aj, Mahadesh, Nongthomba, Upendra

“…Thiomersal (TM) is an excellent preservative that is used in a wide variety of products, like pharmaceuticals, cosmetics, and vaccines, etc. Its usage has been…”
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The association of cysteine to thiomersal attenuates its apoptosis-mediated cytotoxicity in zebrafish by Dutta, Debanjan, Show, Sautan, Pal, Anabadya, Toba, Anifowoshe Abass, Prasad Aj, Mahadesh, Nongthomba, Upendra

“…Thiomersal (TM) is an excellent preservative that is used in a wide variety of products, like pharmaceuticals, cosmetics, and vaccines, etc. Its usage has been…”
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