Search Results - "Prasad, Kavya"

Allosteric Interactions between Adenosine A2A and Dopamine D2 Receptors in Heteromeric Complexes: Biochemical and Pharmacological Characteristics, and Opportunities for PET Imaging by Prasad, Kavya, de Vries, Erik F. J., Elsinga, Philip H., Dierckx, Rudi A. J. O., van Waarde, Aren

“…Adenosine and dopamine interact antagonistically in living mammals. These interactions are mediated via adenosine A2A and dopamine D2 receptors (R)…”
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Impact of an Adenosine A2A Receptor Agonist and Antagonist on Binding of the Dopamine D2 Receptor Ligand [11C]raclopride in the Rodent Striatum by Prasad, Kavya, de Vries, Erik F. J., Sijbesma, Jürgen W. A., Garcia-Varela, Lara, Vazquez-Matias, Daniel A., Moraga-Amaro, Rodrigo, Willemsen, Antoon T. M., Dierckx, Rudi A. J. O., van Waarde, Aren

“…Adenosine A2A and dopamine D2 receptors in the basal ganglia form heterotetrameric structures that are involved in the regulation of motor activity and…”
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Serum Cystatin C Levels as a Predictor of Severity and Mortality Among Patients With COVID-19 Infection by Prasad, Kavya, Kulkarni, Ashwin, K, Navikala, Gowda, Vanitha, Shaikh, Mohammed Aslam

“…Introduction: The pandemic caused by SARS Corona Virus-2 (COVID-19) has caused widespread mortality globally. The hallmark of the disease is the "cytokine…”
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Feasibility of safe outpatient treatment in pediatric patients following intraventricular radioimmunotherapy with 131I-omburtamab for leptomeningeal disease by Prasad, Kavya, Serencsits, Brian E., Chu, Bae P., Dauer, Lawrence T., Donzelli, Maria, Basu, Ellen, Kramer, Kim, Pandit-Taskar, Neeta

“…Background Radiolabeled antibody 131 I-omburtamab was administered intraventricularly in patients with leptomeningeal disease under an institutionally approved…”
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Prenatal infection and adolescent social adversity affect microglia, synaptic density, and behavior in male rats by Guerrin, Cyprien G.J., Prasad, Kavya, Vazquez-Matias, Daniel A., Zheng, Jing, Franquesa-Mullerat, Maria, Barazzuol, Lara, Doorduin, Janine, de Vries, Erik F.J.

“…Maternal infection during pregnancy and childhood social trauma have been associated with neurodevelopmental and affective disorders, such as schizophrenia,…”
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Social adversity during juvenile age but not adulthood increases susceptibility to an immune challenge later in life by Guerrin, Cyprien G.J., Doorduin, Janine, Prasad, Kavya, Vazquez-Matias, Daniel A., Barazzuol, Lara, de Vries, Erik F.J.

“…Adverse experiences in early life can increase mental vulnerability to immune challenges experienced later in life, which may induce the development of…”
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A balancing act: how whole-genome doubling and aneuploidy interact in human cancer by Prasad, Kavya, Ben-David, Uri

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Whole-Genome Duplication Shapes the Aneuploidy Landscape of Human Cancers by Prasad, Kavya, Bloomfield, Mathew, Levi, Hagai, Keuper, Kristina, Bernhard, Sara V, Baudoin, Nicolaas C, Leor, Gil, Eliezer, Yonatan, Giam, Maybelline, Wong, Cheng Kit, Rancati, Giulia, Storchová, Zuzana, Cimini, Daniela, Ben-David, Uri

“…Aneuploidy is a hallmark of cancer with tissue-specific prevalence patterns that suggest it plays a driving role in cancer initiation and progression. However,…”
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Theranostic Intratumoral Convection-Enhanced Delivery of 124 I-Omburtamab in Patients with Diffuse Intrinsic Pontine Glioma: Pharmacokinetics and Lesion Dosimetry by Pandit-Taskar, Neeta, Zanzonico, Pat B, Grkovski, Milan, Donzelli, Maria, Vietri, Scott M, Horan, Christopher, Serencsits, Brian, Prasad, Kavya, Lyashchenko, Serge, Kramer, Kim, Dunkel, Ira J, Souweidane, Mark M

“…Diffuse intrinsic pontine glioma (DIPG) is a rare childhood malignancy with poor prognosis. There are no effective treatment options other than external beam…”
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Theranostic Intratumoral Convection-Enhanced Delivery of 124I-Omburtamab in Patients with Diffuse Intrinsic Pontine Glioma: Pharmacokinetics and Lesion Dosimetry by Pandit-Taskar, Neeta, Zanzonico, Pat B, Grkovski, Milan, Donzelli, Maria, Vietri, Scott M, Horan, Christopher, Serencsits, Brian, Prasad, Kavya, Lyashchenko, Serge, Kramer, Kim, Dunkel, Ira J, Souweidane, Mark M

“…Diffuse intrinsic pontine glioma (DIPG) is a rare childhood malignancy with poor prognosis. There are no effective treatment options other than external beam…”
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Synthesis and preclinical evaluation of [18F]AlF-NODA-MP-C6-CTHRSSVVC as a PET tracer for CD163-positive tumor-infiltrating macrophages by Fernandes, Bruna, Antunes, Ines F., Prasad, Kavya, Vazquez-Matias, Daniel Aaron, De Mattos, Eduardo Preusser, Szymanski, Wiktor, Jeckel, Cristina Maria Moriguchi, de Vries, Erik F.J., Elsinga, Philip H.

“…Positron emission tomography (PET) can provide information about tumor-associated macrophage (TAM) infiltration, as long as a suitable tracer is available…”
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Effects of the adenosine A2A receptor antagonist KW6002 on the dopaminergic system, motor performance, and neuroinflammation in a rat model of Parkinson's disease by Prasad, Kavya, de Vries, Erik F.J., van der Meiden, Esther, Moraga-Amaro, Rodrigo, Vazquez-Matias, Daniel Aaron, Barazzuol, Lara, Dierckx, Rudi A.J.O., van Waarde, Aren

“…Adenosine A2A-receptors (A2AR) and dopamine D2-receptors (D2R) are known to work together in a synergistic manner. Inhibiting A2ARs by genetic or…”
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Feasibility of safe outpatient treatment in pediatric patients following intraventricular radioimmunotherapy with 131 I-omburtamab for leptomeningeal disease by Prasad, Kavya, Serencsits, Brian E, Chu, Bae P, Dauer, Lawrence T, Donzelli, Maria, Basu, Ellen, Kramer, Kim, Pandit-Taskar, Neeta

“…Radiolabeled antibody I-omburtamab was administered intraventricularly in patients with leptomeningeal disease under an institutionally approved study…”
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Optimizing Regulatory Reviews for Clinical Protocols that Use Radiopharmaceuticals: Findings of the University of Pennsylvania Radiation Research Safety Committee by Rhodes, Sylvia S, Jesikiewicz, Janelle E, Yegya-Raman, Nikhil, Prasad, Kavya, Dreyfuss, Alexandra, Mankoff, David A, Taunk, Neil K

“…Institutional radiation safety committees review research studies with radiation exposure. However, ensuring that the potential patient benefit and knowledge…”
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Maternal infection during pregnancy aggravates the behavioral response to an immune challenge during adolescence in female rats by Guerrin, Cyprien G.J., de Vries, Erik F.J., Prasad, Kavya, Vazquez-Matias, Daniel A., Manusiwa, Lesley E., Barazzuol, Lara, Doorduin, Janine

“…Prenatal and early postnatal infection have been associated with changes in microglial activity and the development of psychiatric disorders. Here, we…”
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Silencing of H4R inhibits the production of IL-1β through SAPK/JNK signaling in human mast cells by Ebenezer, Angel Jemima, Prasad, Kavya, Rajan, Sanjana, Thangam, Elden Berla

“…Context: Mast cell (MC) activation through H4R releases various inflammatory mediators which are associated with allergic asthma. Objectives: To investigate…”
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Impact of an Adenosine A2A Receptor Agonist and Antagonist on Binding of the Dopamine D2 Receptor Ligand 11Craclopride in the Rodent Striatum by Prasad, Kavya, de Vries, Erik F J, Sijbesma, Jürgen W A, Garcia-Varela, Lara, Vazquez-Matias, Daniel A, Moraga-Amaro, Rodrigo, Willemsen, Antoon T M, Dierckx, Rudi A J O, van Waarde, Aren

“…Adenosine A2A and dopamine D2 receptors in the basal ganglia form heterotetrameric structures that are involved in the regulation of motor activity and…”
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INFLUENCE OF A2A TREATMENT ON DEPRESSIVE‑LIKE BEHAVIOR AND D2‑RECEPTOR AVAILABILITY IN RATS EXPOSED TO REPEATED SOCIAL DEFEAT by Matias, Daniel A Vazquez, Henry, Samia, Guerrin, Cyprien GJ, Prasad, Kavya, Doorduin, Janine, de Vries, Erik FJ

“…The interaction between the dopaminergic and adenosinergic systems in depressive phenotypes remains largely unexplored. This study aimed to investigate the…”
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Impact of an Adenosine A 2A Receptor Agonist and Antagonist on Binding of the Dopamine D 2 Receptor Ligand [ 11 C]raclopride in the Rodent Striatum by Prasad, Kavya, de Vries, Erik F J, Sijbesma, Jürgen W A, Garcia-Varela, Lara, Vazquez-Matias, Daniel A, Moraga-Amaro, Rodrigo, Willemsen, Antoon T M, Dierckx, Rudi A J O, van Waarde, Aren

“…Adenosine A and dopamine D receptors in the basal ganglia form heterotetrameric structures that are involved in the regulation of motor activity and…”
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Effects of the adenosine A 2A receptor antagonist KW6002 on the dopaminergic system, motor performance, and neuroinflammation in a rat model of Parkinson's disease by Prasad, Kavya, de Vries, Erik F J, van der Meiden, Esther, Moraga-Amaro, Rodrigo, Vazquez-Matias, Daniel Aaron, Barazzuol, Lara, Dierckx, Rudi A J O, van Waarde, Aren

“…Adenosine A -receptors (A R) and dopamine D -receptors (D R) are known to work together in a synergistic manner. Inhibiting A Rs by genetic or pharmacological…”
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