Search Results - "Prasad, Bodhayan"

ATRPred: A machine learning based tool for clinical decision making of anti-TNF treatment in rheumatoid arthritis patients by Prasad, Bodhayan, McGeough, Cathy, Eakin, Amanda, Ahmed, Tan, Small, Dawn, Gardiner, Philip, Pendleton, Adrian, Wright, Gary, Bjourson, Anthony J, Gibson, David S, Shukla, Priyank

“…Rheumatoid arthritis (RA) is a chronic autoimmune condition, characterised by joint pain, damage and disability, which can be addressed in a high proportion of…”
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Leukaemia exposure alters the transcriptional profile and function of BCR::ABL1 negative macrophages in the bone marrow niche by Dawson, Amy, Zarou, Martha M., Prasad, Bodhayan, Bittencourt-Silvestre, Joana, Zerbst, Désirée, Himonas, Ekaterini, Hsieh, Ya-Ching, van Loon, Isabel, Blanco, Giovanny Rodriguez, Ianniciello, Angela, Kerekes, Zsombor, Krishnan, Vaidehi, Agarwal, Puneet, Almasoudi, Hassan, McCluskey, Laura, Hopcroft, Lisa E. M., Scott, Mary T., Baquero, Pablo, Dunn, Karen, Vetrie, David, Copland, Mhairi, Bhatia, Ravi, Coffelt, Seth B., Tiong, Ong Sin, Wheadon, Helen, Zanivan, Sara, Kirschner, Kristina, Helgason, G. Vignir

“…Macrophages are fundamental cells of the innate immune system that support normal haematopoiesis and play roles in both anti-cancer immunity and tumour…”
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Simvastatin is associated with superior lipid and glycaemic control to atorvastatin and reduced levels of incident Type 2 diabetes, in men and women, in the UK Biobank by English, Andrew R., Prasad, Bodhayan, McGuigan, Declan H., Horigan, Geraldine, O’Kane, Maurice, Bjourson, Anthony J., Shukla, Priyank, Kelly, Catriona, McClean, Paula L.

“…Introduction Cardiovascular disease (CVD) is the leading cause of mortality in people with Type 2 diabetes mellitus (T2DM). Statins reduce low‐density…”
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muSignAl: An algorithm to search for multiple omic signatures with similar predictive performance by Prasad, Bodhayan, Bjourson, Anthony J., Shukla, Priyank

“…Multidimensional omic datasets often have correlated features leading to the possibility of discovering multiple biological signatures with similar predictive…”
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Data-driven patient stratification of UK Biobank cohort suggests five endotypes of multimorbidity by Prasad, Bodhayan, Bjourson, Anthony J, Shukla, Priyank

“…Multimorbidity generally refers to concurrent occurrence of multiple chronic conditions. These patients are inherently at high risk and often lead a poor…”
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Leukaemia Exposure Alters the Transcriptional Profile and Function of Macrophages in the Bone Marrow Niche by Zarou, Martha M., Dawson, Amy, Prasad, Bodhayan, Bittencourt-Silvestre, Joana, Zerbst, Désirée, Rodriguez Blanco, Giovanny, Scott, Mary, Dunn, Karen, Krishnan, Vaidehi, Copland, Mhairi, Vetrie, David, Bhatia, Ravi, Coffelt, Seth, Ong, S.Tiong, Wheadon, Helen, Zanivan, Sara, Kirschner, Kristina, Helgason, G. Vignir

“…These authors contributed equally to this work: Martha M. Zarou & Amy Dawson Macrophages are fundamental cells of the innate immune system. Bone marrow (BM)…”
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Arginine dependency is a therapeutically exploitable vulnerability in chronic myeloid leukaemic stem cells by Rattigan, Kevin M, Zarou, Martha M, Brabcova, Zuzana, Prasad, Bodhayan, Zerbst, Désirée, Sarnello, Daniele, Kalkman, Eric R, Ianniciello, Angela, Scott, Mary T, Dunn, Karen, Shokry, Engy, Sumpton, David, Copland, Mhairi, Tardito, Saverio, Vande Voorde, Johan, Mussai, Francis, Cheng, Paul, Helgason, G Vignir

“…To fuel accelerated proliferation, leukaemic cells undergo metabolic deregulation, which can result in specific nutrient dependencies. Here, we perform an…”
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Immuno-informatics analysis predicts B and T cell consensus epitopes for designing peptide vaccine against SARS-CoV-2 with 99.82% global population coverage by Shukla, Priyank, Pandey, Preeti, Prasad, Bodhayan, Robinson, Tony, Purohit, Rituraj, D’Cruz, Leon G, Tambuwala, Murtaza M, Mutreja, Ankur, Harkin, Jim, Rai, Taranjit Singh, Murray, Elaine K, Gibson, David S, Bjourson, Anthony J

“…Abstract The current global pandemic due to Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has taken a substantial number of lives across the…”
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