Search Results - "Prakash, Mansi"

Defining parameters of specificity for bioluminescent optogenetic activation of neurons using in vitro multi electrode arrays (MEA) by Prakash, Mansi, Medendorp, William E., Hochgeschwender, Ute

“…In Bioluminescent Optogenetics (BL‐OG) a biological, rather than a physical, light source is used to activate light‐sensing opsins, such as channelrhodopsins…”
Get full text

Diverse pathological implications of YKL-40: Answers may lie in ‘outside-in’ signaling by Prakash, Mansi, Bodas, Manish, Prakash, Divya, Nawani, Neelu, Khetmalas, Madhukar, Mandal, Abul, Eriksson, Cecilia

“…The developing paradigms about YKL-40, a member of the “mammalian chitinase-like proteins”, from across the globe, project it as a vital parameter for the…”
Get full text

Bioluminescence‐driven optogenetic activation of transplanted neural precursor cells improves motor deficits in a Parkinson's disease mouse model by Zenchak, Jessica R., Palmateer, Brandon, Dorka, Nicolai, Brown, Tariq M., Wagner, Lina‐Marie, Medendorp, William E., Petersen, Eric D., Prakash, Mansi, Hochgeschwender, Ute

“…The need to develop efficient therapies for neurodegenerative diseases is urgent, especially given the increasing percentages of the population living longer,…”
Get full text

Improved Locomotor Recovery in a Rat Model of Spinal Cord Injury by BioLuminescent-OptoGenetic (BL-OG) Stimulation with an Enhanced Luminopsin by Ikefuama, Ebenezer C, Kendziorski, Griffin E, Anderson, Kevin, Shafau, Lateef, Prakash, Mansi, Hochgeschwender, Ute, Petersen, Eric D

“…Irrespective of the many strategies focused on dealing with spinal cord injury (SCI), there is still no way to restore motor function efficiently or an…”
Get full text

Restoring Function After Severe Spinal Cord Injury Through BioLuminescent-OptoGenetics by Petersen, Eric D, Sharkey, Erik D, Pal, Akash, Shafau, Lateef O, Zenchak-Petersen, Jessica, Peña, Alex J, Aggarwal, Anu, Prakash, Mansi, Hochgeschwender, Ute

“…The ability to manipulate specific neuronal populations of the spinal cord following spinal cord injury (SCI) could prove highly beneficial for rehabilitation…”
Get full text

Selective control of synaptically-connected circuit elements by all-optical synapses by Prakash, Mansi, Murphy, Jeremy, St Laurent, Robyn, Friedman, Nina, Crespo, Emmanuel L., Bjorefeldt, Andreas, Pal, Akash, Bhagat, Yuvraj, Kauer, Julie A., Shaner, Nathan C., Lipscombe, Diane, Moore, Christopher I., Hochgeschwender, Ute

“…Understanding percepts, engrams and actions requires methods for selectively modulating synaptic communication between specific subsets of interconnected…”
Get full text

Selective postnatal excitation of neocortical pyramidal neurons results in distinctive behavioral and circuit deficits in adulthood by Medendorp, William E., Bjorefeldt, Andreas, Crespo, Emmanuel L., Prakash, Mansi, Pal, Akash, Waddell, Madison L., Moore, Christopher I., Hochgeschwender, Ute

“…In genetic and pharmacological models of neurodevelopmental disorders, and human data, neural activity is altered within the developing neocortical network…”
Get full text

Bioluminescent optogenetic (BL-OG) activation of neurons during mouse postnatal brain development by Crespo, Emmanuel L., Prakash, Mansi, Bjorefeldt, Andreas, Medendorp, William E., Shaner, Nathan C., Lipscombe, Diane, Moore, Christopher I., Hochgeschwender, Ute

“…Bioluminescent optogenetics (BL-OG) allows activation of photosensory proteins, such as opsins, by either fiberoptics or by administering a luciferin. BL-OG…”
Get full text

Differential Requirement for H2AX and 53BP1 in Organismal Development and Genome Maintenance in the Absence of Poly(ADP)ribosyl Polymerase 1 by Orsburn, Benjamin, Escudero, Beatriz, Prakash, Mansi, Gesheva, Silvia, Liu, Guosheng, Huso, David L., Franco, Sonia

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Actinomycetes: A Repertory of Green Catalysts with a Potential Revenue Resource by Kapadnis, Balasaheb, Mandal, Abul, Bodas, Manish, Prakash, Mansi, Nawani, Neelu, Prakash, Divya, Khetmalas, Madhukar

“…Biocatalysis, one of the oldest technologies, is becoming a favorable alternative to chemical processes and a vital part of green technology. It is an…”
Get full text

Hyaluronan-binding protein 1 (HABP1/p32/gC1qR) induces melanoma cell migration and tumor growth by NF-kappa B dependent MMP-2 activation through integrin α(v)β(3) interaction by Prakash, Mansi, Kale, Smita, Ghosh, Ilora, Kundu, Gopal C, Datta, Kasturi

“…Cell migration is the hallmark of cancer regulating anchorage independent growth and invasiveness of tumor cells. Hyaluronan (HA), an ECM polysaccharide is…”
Get full text

Hyaluronan-binding protein 1 (HABP1/p32/gC1qR) induces melanoma cell migration and tumor growth by NF-kappa B dependent MMP-2 activation through integrin α vβ 3 interaction by Prakash, Mansi, Kale, Smita, Ghosh, Ilora, Kundu, Gopal C., Datta, Kasturi

“…Cell migration is the hallmark of cancer regulating anchorage independent growth and invasiveness of tumor cells. Hyaluronan (HA), an ECM polysaccharide is…”
Get full text

Efficient opto- and chemogenetic control in a single molecule driven by FRET-modified bioluminescence by Björefeldt, Andreas, Murphy, Jeremy, Crespo, Emmanuel L, Lambert, Gerard G, Prakash, Mansi, Ikefuama, Ebenezer C, Friedman, Nina, Brown, Tariq M, Lipscombe, Diane, Moore, Christopher I, Hochgeschwender, Ute, Shaner, Nathan C

“…Bioluminescent optogenetics (BL-OG) offers a unique and powerful approach to manipulate neural activity both opto- and chemogenetically using a single actuator…”
Get full text

ATM and 53BP1 Function in Nonoverlapping Pathways to Suppress T Lineage Lymphomagenesis by Rybanska, Ivana, Chou, Jeremy, Prakash, Mansi, Huso, David, Franco, Sonia

“…Abstract 2374 In response to DNA double-strand breaks (DSB), mammalian cells activate the DNA Damage Response (DDR), a network of factors that promotes their…”
Get full text

Engineering luminopsins with improved coupling efficiencies by Slaviero, Ashley N, Gorantla, Nipun, Simkins, Jacob, Crespo, Emmanuel L, Ikefuama, Ebenezer C, Tree, Maya O, Prakash, Mansi, Björefeldt, Andreas, Barnett, Lauren M, Lambert, Gerard G, Lipscombe, Diane, Moore, Christopher I, Shaner, Nathan C, Hochgeschwender, Ute

“…Luminopsins (LMOs) are bioluminescent-optogenetic tools with a luciferase fused to an opsin that allow bimodal control of neurons by providing both optogenetic…”
Get full text

53BP1 is limiting for NHEJ repair in ATM-deficient model systems that are subjected to oncogenic stress or radiation by Rybanska-Spaeder, Ivana, Reynolds, Taylor L, Chou, Jeremy, Prakash, Mansi, Jefferson, Tameca, Huso, David L, Desiderio, Stephen, Franco, Sonia

“…The DNA damage response (DDR) factors ataxia telangiectasia mutated (ATM) and p53 binding protein 1 (53BP1) function as tumor suppressors in humans and mice,…”
Get full text

Diverse pathological implications of YKL-40: Answers may lie in aoutside-ina signaling by Prakash, Mansi, Bodas, Manish, Prakash, Divya, Nawani, Neelu, Khetmalas, Madhukar, Mandal, Abul, Eriksson, Cecilia

“…The developing paradigms about YKL-40, a member of the amammalian chitinase-like proteinsa, from across the globe, project it as a vital parameter for the…”
Get full text

53BP1 is limiting for nonhomologous end-joining in ATM-deficient cells subjected to oncogenic stress or radiation by Rybanska-Spaeder, Ivana, Reynolds, Taylor L., Chou, Jeremy, Prakash, Mansi, Jefferson, Tameca, Huso, David L., Desiderio, Stephen, Franco, Sonia

“…DNA Damage Response (DDR) factors Ataxia Telangiectasia Mutated (ATM) and p53 Binding Protein 1 (53BP1) function as tumor suppressors in humans and mice, but…”
Get full text

Hyaluronan-binding protein 1 (HABP1/p32/gC1qR) induces melanoma cell migration and tumor growth by NF-kappa B dependent MMP-2 activation through integrin αvβ3 interaction by Prakash, Mansi, Kale, Smita, Ghosh, Ilora, Kundu, Gopal C., Datta, Kasturi

Get full text

MULTIFUNCTIONAL CHARACTERIZATION OF HYALURONAN BINDING PROTEIN 1 OF HUMAN AS APOPTOTIC INDUCER AND ACTIVATOR OF MATRIX METALLOPROTEASES by Chowdhury, Anindya Roy, Prakash, Mansi, Banerjee, Bhaswati, Ghosh, Ilora, Datta, Kasturi

“…Hyaluronan, an important constitutent of the extracellular matrix (ECM) is known to have multifaceted regulations through its different ligands like hyaluronic…”
Get full text