Search Results - "Prajapati, Vijay Kumar"
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Drug targeting to infectious diseases by nanoparticles surface functionalized with special biomolecules
Published in Current medicinal chemistry (01-07-2012)“…The potential to deliver nanoparticles directly into the targeted cells is important in the therapeutic applications for infectious diseases. The possibility…”
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An Oral Formulation of Amphotericin B Attached to Functionalized Carbon Nanotubes Is an Effective Treatment for Experimental Visceral Leishmaniasis
Published in The Journal of infectious diseases (15-01-2012)“…Amphotericin B (AmB), is a highly effective antileishmanial agent used as first-line treatment in different formulations in visceral leishmaniasis endemic…”
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Exploring Leishmania secretory proteins to design B and T cell multi-epitope subunit vaccine using immunoinformatics approach
Published in Scientific reports (15-08-2017)“…Visceral leishmaniasis (VL) is a fatal form of leishmaniasis which affects 70 countries, worldwide. Increasing drug resistance, HIV co-infection, and poor…”
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Novel Immunoinformatics Approaches to Design Multi-epitope Subunit Vaccine for Malaria by Investigating Anopheles Salivary Protein
Published in Scientific reports (18-01-2018)“…Malaria fever has been pervasive for quite a while in tropical developing regions causing high morbidity and mortality. The causal organism is a protozoan…”
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Designing B‐ and T‐cell multi‐epitope based subunit vaccine using immunoinformatics approach to control Zika virus infection
Published in Journal of cellular biochemistry (01-09-2018)“…The Zika virus is a rapidly spreading Aedes mosquito‐borne sickness, which creates an unanticipated linkage birth deformity and neurological turmoil. This…”
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Exploring dengue genome to construct a multi-epitope based subunit vaccine by utilizing immunoinformatics approach to battle against dengue infection
Published in Scientific reports (23-08-2017)“…Dengue is considered as a major health issue which causes a number of deaths worldwide each year; tropical countries are majorly affected by dengue outbreaks…”
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Emerging Role of Circular RNAs as Potential Biomarkers for the Diagnosis of Human Diseases
Published in Advances in experimental medicine and biology (2018)“…In the eukaryotic transcriptome, the evolutionary conserved circular RNAs naturally occur from the family of noncoding RNAs. Circular RNAs possess a unique…”
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Designing of a bispecific antibody against SARS-CoV-2 spike glycoprotein targeting human entry receptors DPP4 and ACE2
Published in Human immunology (01-04-2022)“…COVID-19 originated in Wuhan city, China, in 2019 erupted a global pandemic that had put down nearly 3 million lives and hampered the socio-economic conditions…”
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Differential Expression of miRNA Regulates T Cell Differentiation and Plasticity During Visceral Leishmaniasis Infection
Published in Frontiers in microbiology (25-02-2016)“…Visceral leishmaniasis (VL) is a tropical neglected disease caused by Leishmania donovani, results in significant mortality in the Indian subcontinent. The…”
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Investigation of immunogenic properties of Hemolin from silkworm, Bombyx mori as carrier protein: an immunoinformatic approach
Published in Scientific reports (03-05-2018)“…Infectious diseases are the major cause of high mortality among infants and geriatric patients. Vaccines are the only weapon in our arsenal to defend us…”
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Cytotoxic T-lymphocyte elicited vaccine against SARS-CoV-2 employing immunoinformatics framework
Published in Scientific reports (07-04-2021)“…Development of effective counteragents against the novel coronavirus disease (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)…”
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The use of destructive and nondestructive techniques in concrete nitrogen assessment in plants
Published in Journal of plant nutrition (26-08-2024)“…Nitrogen (N) is the key macronutrient for sustainable growth and higher productivity of crops. Optimized nitrogen-use-efficiency (NUE) enhances productivity…”
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Exploring malaria parasite surface proteins to devise highly immunogenic multi-epitope subunit vaccine for Plasmodium falciparum
Published in Journal of Genetic Engineering and Biotechnology (01-06-2024)“…Malaria has remained a major health concern for decades among people living in tropical and sub-tropical countries. Plasmodium falciparum is one of the…”
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Editorial: Plant products for antiviral therapeutics
Published in Frontiers in pharmacology (17-10-2022)Get full text
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Unusual Case of Resistance to Amphotericin B in Visceral Leishmaniasis in a Region in India Where Leishmaniasis Is Not Endemic
Published in Journal of Clinical Microbiology (01-08-2011)“…Article Usage Stats Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Targeted killing of Leishmania donovani in vivo and in vitro with amphotericin B attached to functionalized carbon nanotubes
Published in Journal of antimicrobial chemotherapy (01-04-2011)“…This study describes the antileishmanial efficacy of the novel drug formulation of amphotericin B (AmB) attached to functionalized carbon nanotubes (f-CNTs)…”
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Characterisation of antimony-resistant Leishmania donovani isolates: Biochemical and biophysical studies and interaction with host cells
Published in International journal for parasitology (01-11-2011)“…[Display omitted] ► Leishmania donovani showing a high EC 50 value against sodium stibogluconate is considered to be resistant or else sensitive. ► Thiol…”
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Prediction of an immunogenic peptide ensemble and multi-subunit vaccine for Visceral leishmaniasis using bioinformatics approaches
Published in Heliyon (01-12-2023)“…Visceral Leishmaniasis (VL) is a neglected tropical disease of public health importance in the Indian subcontinent. Despite consistent elimination initiatives,…”
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