Search Results - "Prajapati, Ritu"
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Isoliquiritigenin, a potent human monoamine oxidase inhibitor, modulates dopamine D1, D3, and vasopressin V1A receptors
Published in Scientific reports (07-12-2021)“…Isoliquiritigenin (= 4,2′,4′-Trihydroxychalcone) (ILG) is a major constituent of the Glycyrrhizae Rhizoma that has significant neuroprotective functions. In…”
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In Vitro Human Monoamine Oxidase Inhibition and Human Dopamine D4 Receptor Antagonist Effect of Natural Flavonoids for Neuroprotection
Published in International journal of molecular sciences (01-11-2023)“…Natural flavone and isoflavone analogs such as 3′,4′,7-trihydroxyflavone (1), 3′,4′,7-trihydroxyisoflavone (2), and calycosin (3) possess significant…”
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Dual modulators of aggregation and dissociation of amyloid beta and tau: In vitro, in vivo, and in silico studies of Uncaria rhynchophylla and its bioactive components
Published in Biomedicine & pharmacotherapy (01-12-2022)“…A prominent characteristic of Alzheimer's disease (AD) is the deposition of both amyloid-β (Aβ) peptide and tau protein in the brain. Aβ and tau not only…”
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Dual regulatory effects of neferine on amyloid-β and tau aggregation studied by in silico, in vitro, and lab-on-a-chip technology
Published in Biomedicine & pharmacotherapy (01-03-2024)“…Alzheimer’s disease (AD) is characterized by the presence of two critical pathogenic factors: amyloid-β (Aβ) and tau. Aβ and tau become neurotoxic aggregates…”
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Monoamine Oxidase Inhibition by Major Tanshinones from Salvia miltiorrhiza and Selective Muscarinic Acetylcholine M4 Receptor Antagonism by Tanshinone I
Published in Biomolecules (Basel, Switzerland) (08-07-2021)“…Monoamine oxidases (MAOs) and muscarinic acetylcholine receptors (mAChRs) are considered important therapeutic targets for Parkinson’s disease (PD). Lipophilic…”
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In Vitro and In Silico Characterization of Kurarinone as a Dopamine D1A Receptor Antagonist and D2L and D4 Receptor Agonist
Published in ACS omega (14-12-2021)“…Alterations in the expression and/or activity of brain G-protein-coupled receptors (GPCRs) such as dopamine D 1 R, D 2L R, D 3 R, and D 4 R, vasopressin V 1A…”
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Isolation and Identification of Bioactive Compounds from the Tuber of Brassica oleracea var. gongylodes
Published in Natural product sciences (01-01-2020)“…Brassica oleracea var. gongylodes (red kohlrabi) is a biennial herbaceous vegetable whose edible bulbotuber-like stem and leaves are consumed globally. Sliced…”
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Isolation and Identification of Bioactive Compounds from the Tuber of Brassica oleracea var. gongylodes
Published in Natural product sciences (2020)“…Brassica oleracea var. gongylodes (red kohlrabi) is a biennial herbaceous vegetable whose edible bulbotuber-like stem and leaves are consumed globally. Sliced…”
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Journal Article -
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Isoliquiritigenin, a potent human monoamine oxidase inhibitor, modulates dopamine D 1 , D 3 , and vasopressin V 1A receptors
Published in Scientific reports (07-12-2021)“…Isoliquiritigenin (= 4,2',4'-Trihydroxychalcone) (ILG) is a major constituent of the Glycyrrhizae Rhizoma that has significant neuroprotective functions. In…”
Get full text
Journal Article -
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PTP1B and α-glucosidase inhibitory activities of the chemical constituents from Hedera rhombea fruits: Kinetic analysis and molecular docking simulation
Published in Phytochemistry (Oxford) (01-05-2022)“…In this study, we present the first investigation of Hedera rhombea Bean fruit, which led to the isolation of six undescribed compounds including two…”
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In Vitro Human Monoamine Oxidase Inhibition and Human Dopamine D[sub.4] Receptor Antagonist Effect of Natural Flavonoids for Neuroprotection
Published in International journal of molecular sciences (01-11-2023)“…Natural flavone and isoflavone analogs such as 3′,4′,7-trihydroxyflavone (1), 3′,4′,7-trihydroxyisoflavone (2), and calycosin (3) possess significant…”
Get full text
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Antioxidant and Antineuroinflammatory Mechanisms of Kaempferol-3‑O‑β‑d‑Glucuronate on Lipopolysaccharide-Stimulated BV2 Microglial Cells through the Nrf2/HO‑1 Signaling Cascade and MAPK/NF-κB Pathway
Published in ACS omega (21-02-2023)“…Aglycone- and glycoside-derived forms of flavonoids exist broadly in plants and foods such as fruits, vegetables, and peanuts. However, most studies focus on…”
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Anti-Glycation, Anti-β-Amyloid Aggregation, and Antioxidant Effect of Cassia Seed-Derived Secondary Metabolites
Published in Journal of food biochemistry (21-10-2023)“…Aggregation and non-enzymatic glycation of amyloidogenic peptides, amyloid-beta (Aβ), and insulin are key features of neuropathology. In this study, we…”
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In Vitro and In Silico Characterization of Kurarinone as a Dopamine D 1A Receptor Antagonist and D 2L and D 4 Receptor Agonist
Published in ACS omega (14-12-2021)“…Alterations in the expression and/or activity of brain G-protein-coupled receptors (GPCRs) such as dopamine D R, D R, D R, and D R, vasopressin V R, and…”
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Monoamine Oxidase Inhibition by Major Tanshinones from Salvia miltiorrhiza and Selective Muscarinic Acetylcholine M 4 Receptor Antagonism by Tanshinone I
Published in Biomolecules (Basel, Switzerland) (08-07-2021)“…Monoamine oxidases (MAOs) and muscarinic acetylcholine receptors (mAChRs) are considered important therapeutic targets for Parkinson's disease (PD). Lipophilic…”
Get full text
Journal Article -
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Deep Dive: Music Genre Classification with Convolutional Neural Networks
Published in 2023 5th International Conference on Advances in Computing, Communication Control and Networking (ICAC3N) (15-12-2023)“…With the emergence of digital music resources like Spotify, SoundCloud, YouTube, iTunes, and Shazam, the face of streaming music has changed. Accessing various…”
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