Search Results - "Prado, Marco Antônio M"
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Acute lung injury is reduced by the α7nAChR agonist PNU‐282987 through changes in the macrophage profile
Published in The FASEB journal (01-01-2017)“…Nicotinic α‐7 acetylcholine receptor (nAChRα7) is a critical regulator of cholinergic anti‐inflammatory actions in several diseases, including acute…”
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2
Long-term endogenous acetylcholine deficiency potentiates pulmonary inflammation in a murine model of elastase-induced emphysema
Published in Scientific reports (05-08-2021)“…Acetylcholine (ACh), the neurotransmitter of the cholinergic system, regulates inflammation in several diseases including pulmonary diseases. ACh is also…”
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3
Lung Edema and Mortality Induced by Intestinal Ischemia and Reperfusion Is Regulated by VAChT Levels in Female Mice
Published in Inflammation (01-08-2021)“…Acute lung injury induced by intestinal ischemia/reperfusion (I/R) is a relevant clinical condition. Acetylcholine (ACh) and the α7 nicotinic ACh receptor…”
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4
Pulmonary inflammation is regulated by the levels of the vesicular acetylcholine transporter
Published in PloS one (27-03-2015)“…Acetylcholine (ACh) plays a crucial role in physiological responses of both the central and the peripheral nervous system. Moreover, ACh was described as an…”
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Alpha-7 Nicotinic Receptor Agonist Protects Mice Against Pulmonary Emphysema Induced by Elastase
Published in Inflammation (01-06-2024)“…Pulmonary emphysema is a primary component of chronic obstructive pulmonary disease (COPD), a life-threatening disorder characterized by lung inflammation and…”
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6
Vesicular acetylcholine transport deficiency potentiates some inflammatory responses induced by diesel exhaust particles
Published in Ecotoxicology and environmental safety (15-01-2019)“…Endogenous acetylcholine (ACh), which depends of the levels of vesicular ACh transport (VAChT) to be released, is the central mediator of the cholinergic…”
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7
Nitric oxide regulates AKT phosphorylation and nuclear translocation in cultured retinal cells
Published in Cellular signalling (01-12-2013)“…Previous studies have shown that nitric oxide (NO) inhibits apoptosis of retinal neurons in culture through the canonical cyclic GMP/protein kinase G…”
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Tx3-4 a toxin from the venom of spider Phoneutria nigriventer blocks calcium channels associated with exocytosis
Published in Neuroscience letters (11-07-2008)“…The purpose of the present work was to investigate the pharmacological action of a calcium channel-blocking toxin from the venom of the spider Phonetic…”
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Effects of VAChT reduction and α7nAChR stimulation by PNU-282987 in lung inflammation in a model of chronic allergic airway inflammation
Published in European journal of pharmacology (05-09-2020)“…The cholinergic anti-inflammatory pathway has been shown to regulate lung inflammation and cytokine release in acute models of inflammation, mainly via α7…”
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10
Towards cellular receptors for prions
Published in Reviews in medical virology (01-11-2003)“…Transmissible spongiform encephalopathies (TSE) are attributed to the conversion of the cellular prion protein (PrPc) into an abnormal isoform (PrPsc). This…”
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11
Antiarrhythmogenic effects of a neurotoxin from the spider Phoneutria nigriventer
Published in Toxicon (Oxford) (01-02-2011)“…In this study, we evaluated the effects of PhKv, a 4584 Da peptide isolated from the spider Phoneutria nigriventer venom, in the isolated rat heart and in…”
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12
Phoneutria spider toxins block ischemia-induced glutamate release, neuronal death, and loss of neurotransmission in hippocampus
Published in Hippocampus (01-11-2009)“…The aim of this study was to investigate the effect of spider toxins on brain injury induced by oxygen deprivation and low glucose (ODLG) insult on slices of…”
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13
AAV-mediated neuronal expression of an scFv antibody selective for Aβ oligomers protects synapses and rescues memory in Alzheimer models
Published in Molecular therapy (01-02-2023)“…The accumulation of soluble oligomers of the amyloid-β peptide (AβOs) in the brain has been implicated in synapse failure and memory impairment in Alzheimer’s…”
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14
The Effect of Spider Toxin PhTx3-4, ω-Conotoxins MVIIA and MVIIC on Glutamate Uptake and on Capsaicin-Induced Glutamate Release and [Ca2+]i in Spinal cord Synaptosomes
Published in Cellular and molecular neurobiology (01-03-2011)“…In spinal cord synaptosomes, the spider toxin PhTx3-4 inhibited capsaicin-stimulated release of glutamate in both calcium-dependent and -independent manners…”
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15
Neuroprotective effect on brain injury by neurotoxins from the spider Phoneutria nigriventer
Published in Neurochemistry international (01-10-2006)“…The role of calcium channels blockers in ischemic condition has been well documented. The PhTx3 neurotoxic fraction of the spider Phoneutria nigriventer venom…”
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16
Acute lung injury is reduced by the α7nAChR agonist PNU-282987 through changes in the macrophage profile
Published in The FASEB journal (01-01-2017)“…Nicotinic α-7 acetylcholine receptor (nAChRα7) is a critical regulator of cholinergic anti-inflammatory actions in several diseases, including acute…”
Get full text
Journal Article -
17
Effects of α-scorpion toxin, tityustoxin on the release of [ [formula omitted]] dopamine of rat brain prefrontal cortical slices
Published in Neurochemistry international (2004)“…The effect of tityustoxin (TsTX) on the release of [ 3 H ] dopamine in rat brain prefrontal cortical slices was investigated. The stimulatory effect of TsTX…”
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18
Regulation of vesicular acetylcholine transporter by the activation of excitatory amino acid receptors in the avian retina
Published in Cellular and molecular neurobiology (01-12-2002)“…1. Previous studies have shown that phorbol esters induce protein kinase C (PKC) mediated phosphorylation of the vesicular acetylcholine transporter (VAChT)…”
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19
Inhibition of Na+,K+-ATPase by ouabain opens calcium channels coupled to acetylcholine release in guinea pig myenteric plexus
Published in Journal of neurochemistry (01-04-1996)“…Ouabain, an Na+K+ATPase inhibitor, increases the release of acetylcholine (ACh) from various preparations in a Ca2+ -independent way. However, in other…”
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20
The effect of spider toxin PhTx3-4, ω-conotoxins MVIIA and MVIIC on glutamate uptake and on capsaicin-induced glutamate release and Ca2+i in spinal cord synaptosomes
Published in Cellular and molecular neurobiology (01-03-2011)“…In spinal cord synaptosomes, the spider toxin PhTx3-4 inhibited capsaicin-stimulated release of glutamate in both calcium-dependent and -independent manners…”
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