Search Results - "Prado, Marco AM"

MouseBytes, an open-access high-throughput pipeline and database for rodent touchscreen-based cognitive assessment by Beraldo, Flavio H, Palmer, Daniel, Memar, Sara, Wasserman, David I, Lee, Wai-Jane V, Liang, Shuai, Creighton, Samantha D, Kolisnyk, Benjamin, Cowan, Matthew F, Mels, Justin, Masood, Talal S, Fodor, Chris, Al-Onaizi, Mohammed A, Bartha, Robert, Gee, Tom, Saksida, Lisa M, Bussey, Timothy J, Strother, Stephen S, Prado, Vania F, Winters, Boyer D, Prado, Marco Am

“…Open Science has changed research by making data accessible and shareable, contributing to replicability to accelerate and disseminate knowledge. However, for…”
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Quantitative Tissue Ph Measurement during Cerebral Ischemia Using Amine and Amide Concentration-Independent Detection (AACID) with MRI by McVicar, Nevin, Li, Alex X, Gonçalves, Daniela F, Bellyou, Miranda, Meakin, Susan O, Prado, Marco AM, Bartha, Robert

“…Tissue pH is an indicator of altered cellular metabolism in diseases including stroke and cancer. Ischemic tissue often becomes acidic due to increased…”
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The Transient Receptor Potential Melastatin 2 (TRPM2) Channel Contributes to β-Amyloid Oligomer-Related Neurotoxicity and Memory Impairment by Ostapchenko, Valeriy G, Chen, Megan, Guzman, Monica S, Xie, Yu-Feng, Lavine, Natalie, Fan, Jue, Beraldo, Flavio H, Martyn, Amanda C, Belrose, Jillian C, Mori, Yasuo, MacDonald, John F, Prado, Vania F, Prado, Marco A M, Jackson, Michael F

“…In Alzheimer's disease, accumulation of soluble oligomers of β-amyloid peptide is known to be highly toxic, causing disturbances in synaptic activity and…”
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Physiology of the Prion Protein by Linden, Rafael, Martins, Vilma R, Prado, Marco A. M, Cammarota, Martin, Izquierdo, Ivan, Brentani, Ricardo R

“…Instituto de Biofísica da Universidade Federal do Rio de Janeiro, Rio de Janeiro; Ludwig Institute for Cancer Research, Hospital Alemão Oswaldo Cruz, São…”
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Cholinergic dysfunction in the dorsal striatum promotes habit formation and maladaptive eating by Favier, Mathieu, Janickova, Helena, Justo, Damian, Kljakic, Ornela, Runtz, Léonie, Natsheh, Joman Y, Pascoal, Tharick A, Germann, Jurgen, Gallino, Daniel, Kang, Jun-Ii, Meng, Xiang Qi, Antinora, Christina, Raulic, Sanda, Jacobsen, Jacob Pr, Moquin, Luc, Vigneault, Erika, Gratton, Alain, Caron, Marc G, Duriez, Philibert, Brandon, Mark P, Neto, Pedro Rosa, Chakravarty, M Mallar, Herzallah, Mohammad M, Gorwood, Philip, Prado, Marco Am, Prado, Vania F, El Mestikawy, Salah

“…Dysregulation of habit formation has been recently proposed as pivotal to eating disorders. Here, we report that a subset of patients suffering from…”
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ChAT-ChR2-EYFP mice have enhanced motor endurance but show deficits in attention and several additional cognitive domains by Kolisnyk, Benjamin, Guzman, Monica S, Raulic, Sanda, Fan, Jue, Magalhães, Ana C, Feng, Guoping, Gros, Robert, Prado, Vania F, Prado, Marco A M

“…Acetylcholine (ACh) is an important neuromodulator in the nervous system implicated in many forms of cognitive and motor processing. Recent studies have used…”
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Cardiomyocyte‐secreted acetylcholine is required for maintenance of homeostasis in the heart by Roy, Ashbeel, Fields, William C., Rocha‐Resende, Cibele, Resende, Rodrigo R., Guatimosim, Silvia, Prado, Vania F., Gros, Robert, Prado, Marco A. M.

“…Heart activity and long‐term function are regulated by the sympathetic and parasympathetic branches of the nervous system. Parasympathetic neurons have…”
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Deletion of the vesicular acetylcholine transporter from pedunculopontine/laterodorsal tegmental neurons modifies gait by Janickova, Helena, Rosborough, Kaie, Al‐Onaizi, Mohammed, Kljakic, Ornela, Guzman, Monica S., Gros, Robert, Prado, Marco A. M., Prado, Vania F.

“…Postural instability and gait disturbances, common disabilities in the elderly and frequently present in Parkinson's disease (PD), have been suggested to be…”
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Forebrain deletion of the vesicular acetylcholine transporter results in deficits in executive function, metabolic, and RNA splicing abnormalities in the prefrontal cortex by Kolisnyk, Benjamin, Al-Onaizi, Mohammed A, Hirata, Pedro H F, Guzman, Monica S, Nikolova, Simona, Barbash, Shahar, Soreq, Hermona, Bartha, Robert, Prado, Marco A M, Prado, Vania F

“…One of the key brain regions in cognitive processing and executive function is the prefrontal cortex (PFC), which receives cholinergic input from basal…”
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Preface: Cholinergic Mechanisms by Prado, Marco A.M., Marchot, Pascale, Silman, Israel

“…This special issue is a companion to the meeting ‘XVth International Symposium on Cholinergic Mechanisms’, and is edited by Israel Silman, Marco Prado and…”
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Stress‐inducible phosphoprotein 1 has unique cochaperone activity during development and regulates cellular response to ischemia via the prion protein by Beraldo, Flavio H., Soares, Iaci N., Goncalves, Daniela F., Fan, Jue, Thomas, Anu A., Santos, Tiago G., Mohammad, Amro H., Roffé, Martin, Calder, Michele D., Nikolova, Simona, Hajj, Glaucia N., Guimaraes, Andre L., Massensini, Andre R., Welch, Ian, Betts, Dean H., Gros, Robert, Drangova, Maria, Watson, Andrew J., Bartha, Robert, Prado, Vania F., Martins, Vilma R., Prado, Marco A. M.

“…Stress‐inducible phosphoprotein 1 (STI1) is part of the chaperone machinery, but it also functions as an extracellular ligand for the prion protein. However,…”
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Role of the atypical vesicular glutamate transporter VGLUT3 in l -DOPA-induced dyskinesia by Gangarossa, Giuseppe, Guzman, Monica, Prado, Vania F, Prado, Marco A.M, Daumas, Stephanie, El Mestikawy, Salah, Valjent, Emmanuel

“…Abstract Parkinson's disease (PD) is characterized by the degeneration of dopaminergic neurons. The gold standard therapy relies on dopamine (DA) replacement…”
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The prion protein ligand, stress-inducible phosphoprotein 1, regulates amyloid-β oligomer toxicity by Ostapchenko, Valeriy G, Beraldo, Flavio H, Mohammad, Amro H, Xie, Yu-Feng, Hirata, Pedro H F, Magalhaes, Ana C, Lamour, Guillaume, Li, Hongbin, Maciejewski, Andrzej, Belrose, Jillian C, Teixeira, Bianca L, Fahnestock, Margaret, Ferreira, Sergio T, Cashman, Neil R, Hajj, Glaucia N M, Jackson, Michael F, Choy, Wing-Yiu, MacDonald, John F, Martins, Vilma R, Prado, Vania F, Prado, Marco A M

“…In Alzheimer's disease (AD), soluble amyloid-β oligomers (AβOs) trigger neurotoxic signaling, at least partially, via the cellular prion protein (PrP(C))…”
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Prion protein in exosomes: partnering Aβ peptides and driving fibrilization by Martins, Vilma R., Prado, Marco A. M.

“…This Editorial highlights a study by Falker and coworkers in which the authors expanded the notion of how prion protein (PrPC) can be involved with the…”
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Elimination of the vesicular acetylcholine transporter in the striatum reveals regulation of behaviour by cholinergic-glutamatergic co-transmission by Guzman, Monica S, De Jaeger, Xavier, Raulic, Sanda, Souza, Ivana A, Li, Alex X, Schmid, Susanne, Menon, Ravi S, Gainetdinov, Raul R, Caron, Marc G, Bartha, Robert, Prado, Vania F, Prado, Marco A M

“…Cholinergic neurons in the striatum are thought to play major regulatory functions in motor behaviour and reward. These neurons express two vesicular…”
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Quantal release of acetylcholine in mice with reduced levels of the vesicular acetylcholine transporter by Lima, Ricardo de Freitas, Prado, Vania F, Prado, Marco A.M, Kushmerick, Christopher

“…J. Neurochem. (2010) 113, 943-951. Mammalian motor nerve terminals contain hundreds of thousands of synaptic vesicles, but only a fraction of these vesicles is…”
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Mice deficient for striatal Vesicular Acetylcholine Transporter (VAChT) display impaired short-term but normal long-term object recognition memory by Palmer, Daniel, Creighton, Samantha, Prado, Vania F., Prado, Marco A.M., Choleris, Elena, Winters, Boyer D.

“…•Studied mice deficient for the Vesicular Acetylcholine Transporter in the striatum.•Impairment seen in object recognition memory with short retention…”
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Mice with selective elimination of striatal acetylcholine release are lean, show altered energy homeostasis and changed sleep/wake cycle by Guzman, Monica S., Jaeger, Xavier, Drangova, Maria, Prado, Marco A. M., Gros, Robert, Prado, Vania F.

“…Cholinergic neurons are known to regulate striatal circuits; however, striatal‐dependent physiological outcomes influenced by acetylcholine (ACh) are still…”
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Increased prion protein processing and expression of metabotropic glutamate receptor 1 in a mouse model of Alzheimer's disease by Ostapchenko, Valeriy G., Beraldo, Flavio H., Guimarães, Andre L. S., Mishra, Sanju, Guzman, Monica, Fan, Jue, Martins, Vilma R., Prado, Vania F., Prado, Marco A. M.

“…Prion protein (PrPC), a glycosylphosphatidylinositol‐anchored protein corrupted in prion diseases, has been shown recently to interact with group I…”
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Autonomic cardiocirculatory control in mice with reduced expression of the vesicular acetylcholine transporter by Durand, Marina T, Becari, Christiane, Tezini, Geisa C S V, Fazan, Jr, Rubens, Oliveira, Mauro, Guatimosim, Silvia, Prado, Vania F, Prado, Marco A M, Salgado, Helio C

“…In cardiovascular diseases, sympathetic tone has been comprehensively studied, whereas parasympathetic tone has received minor attention. The vesicular ACh…”
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