Search Results - "Prado, Alejandro Ferraz"
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“K-Powder” Exposure during Adolescence Elicits Psychiatric Disturbances Associated with Oxidative Stress in Female Rats
Published in Pharmaceuticals (Basel, Switzerland) (01-11-2022)“…Ketamine, also called ‘K-powder’ by abusers, an analog of phencyclidine, primarily acts as an antagonist of N-methyl-D-aspartic acid (NMDA) receptors,…”
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The role of matrix metalloproteinase-9 in cardiac remodeling and dysfunction and as a possible blood biomarker in heart failure
Published in Pharmacological research (01-08-2024)“…Heart failure (HF) is the leading cause of morbidity and mortality in cardiovascular diseases, being responsible for many hospitalizations annually. HF is…”
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Matrix Metalloproteinase 2 as a Pharmacological Target in Heart Failure
Published in Pharmaceuticals (Basel, Switzerland) (25-07-2022)“…Heart failure (HF) is an acute or chronic clinical syndrome that results in a decrease in cardiac output and an increase in intracardiac pressure at rest or…”
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MMP-2 and its implications on cardiac function and structure: Interplay with inflammation in hypertension
Published in Biochemical pharmacology (01-09-2023)“…[Display omitted] Hypertension is one of the leading risk factors for the development of heart failure. Despite being a multifactorial disease, in recent…”
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BmooMPα-I, a Metalloproteinase Isolated from Bothrops moojeni Venom, Reduces Blood Pressure, Reverses Left Ventricular Remodeling and Improves Cardiac Electrical Conduction in Rats with Renovascular Hypertension
Published in Toxins (05-11-2022)“…BmooMPα-I has kininogenase activity, cleaving kininogen releasing bradykinin and can hydrolyze angiotensin I at post-proline and aspartic acid positions,…”
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Studies on the Phytochemical Profile of Ocimum basilicum var. minimum (L.) Alef. Essential Oil, Its Larvicidal Activity and In Silico Interaction with Acetylcholinesterase against Aedes aegypti (Diptera: Culicidae)
Published in International journal of molecular sciences (01-10-2022)“…Aedes aegypti L. (Diptera: Culicidae) is an important transmitter of diseases in tropical countries and controlling the larvae of this mosquito helps to reduce…”
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One binge-type cycle of alcohol plus ketamine exposure induces emotional-like disorders associated with oxidative damage in adolescent female rats
Published in Biomedicine & pharmacotherapy (01-06-2023)“…Drug abuse is a global public health problem among adolescents, with alcohol often used in association with other psychotropic drugs, such as ketamine…”
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Potential Biotechnological Applications of Venoms from the Viperidae Family in Central America for Thrombosis
Published in Toxins (08-03-2024)“…Central America is home to one of the most abundant herpetofauna in the Americas, occupying only 7% of the continent's total area. Vipers and lizards are among…”
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C-type natriuretic peptide-induced relaxation through cGMP-dependent protein kinase and SERCA activation is impaired in two kidney-one clip rat aorta
Published in Life sciences (1973) (01-05-2021)“…Hypertension underlies endothelial dysfunction, and activation of vasorelaxation signaling with low dependence on nitric oxide (NO) represents a good…”
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In utero and lactational exposure to methylmercury elicits physical-chemical and morphological damages in the alveolar bone of offspring rats: The first toxicological findings
Published in Chemosphere (Oxford) (01-12-2022)“…Methylmercury (MeHg) is the most common organic form of mercury (Hg) that humans are exposed and is considered an environmental pollutant. Several populations…”
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Fluoride exposure duringintrauterine and lactation periods promotes changes in the offspring rats' alveolar bone
Published in Chemosphere (Oxford) (01-11-2022)“…The importance of fluoride (F) for oral health is well established in the literature. However, evidence suggests that excessive exposure to this mineral is…”
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BmooMPα-I, a Metalloproteinase Isolated from IBothrops moojeni/I Venom, Reduces Blood Pressure, Reverses Left Ventricular Remodeling and Improves Cardiac Electrical Conduction in Rats with Renovascular Hypertension
Published in Toxins (01-11-2022)“…BmooMPα-I has kininogenase activity, cleaving kininogen releasing bradykinin and can hydrolyze angiotensin I at post-proline and aspartic acid positions,…”
Get full text
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Potential Biotechnological Applications of Venoms from the IViperidae/I Family in Central America for Thrombosis
Published in Toxins (01-03-2024)“…Central America is home to one of the most abundant herpetofauna in the Americas, occupying only 7% of the continent’s total area. Vipers and lizards are among…”
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Relaxation induced by the nitric oxide donor and cyclooxygenase inhibitor NCX2121 in renal hypertensive rat aortas
Published in European journal of pharmaceutical sciences (30-09-2017)“…There is an imbalance between contractile and relaxing endothelial factors in hypertension which induces vascular dysfunction. It involves cyclooxygenase (COX)…”
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Aqueous Coriandrum sativum L. extract promotes neuroprotection against motor changes and oxidative damage in rat progeny after maternal exposure to methylmercury
Published in Food and chemical toxicology (01-11-2019)“…This study aimed to investigate the effects of Coriandrum sativum aqueous extract (CSAE) on the rat progeny of mothers exposed to methylmercury (MeHg). The…”
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Use of a Recombinant Fluorescent MMP‐2 as a Reporter for Tracking the Involvement of This Protease in Target Organ Damage Found in Cardiovascular Diseases
Published in The FASEB journal (01-04-2013)“…Abstract only Matrix Metalloproteinase 2 (MMP‐2) is elevated in hypertensive heart and vessel remodeling, being also highly expressed in organs that show…”
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Matrix Metalloproteinase 2 (MMP‐2) Increases Atherosclerotic Aorta Rings Vasoconstriction
Published in The FASEB journal (01-04-2013)“…Abstract only The present study aimed to evaluate the vascular function of atherosclerotic aortic rings after intraluminal injection of MMP‐2. Thoracic aorta…”
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Exogenous Matrix Metalloproteinase 2 (MMP-2) Enters the Vascular Tissue and Induces Increased Aortic Contraction Via ROS Generation
Published in Free radical biology & medicine (01-11-2013)Get full text
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Prospección fitoquímica y actividad antiplasmódica del extracto hexánico de Montrichardia linifera (Arruda) Schott
Published in Revista cubana de plantas medicinales (01-06-2011)“…Introducción: los extractos de M. linifera presentaron alta toxicidad para Artemia salina, lo cual sugiere un alto potencial biológico para actividad…”
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