Search Results - "Pradines, Joel"

Noise-Based Switches and Amplifiers for Gene Expression by Hasty, Jeff, Pradines, Joel, Dolnik, Milos, Collins, J. J.

“…The regulation of cellular function is often controlled at the level of gene transcription. Such genetic regulation usually consists of interacting networks,…”
Get full text

Equivalent Gene Expression Profiles between Glatopa™ and Copaxone by D'Alessandro, Josephine S, Duffner, Jay, Pradines, Joel, Capila, Ishan, Garofalo, Kevin, Kaundinya, Ganesh, Greenberg, Benjamin M, Kantor, Daniel, Ganguly, Tanmoy C

“…Glatopa™ is a generic glatiramer acetate recently approved for the treatment of patients with relapsing forms of multiple sclerosis. Gene expression profiling…”
Get full text

Multiomic study of skin, peripheral blood, and serum: is serum proteome a reflection of disease process at the end-organ level in systemic sclerosis? by Farutin, Victor, Kurtagic, Elma, Pradines, Joël R, Capila, Ishan, Mayes, Maureen D, Wu, Minghua, Manning, Anthony M, Assassi, Shervin

“…Serum proteins can be readily assessed during routine clinical care. However, it is unclear to what extent serum proteins reflect the molecular dysregulations…”
Get full text

Enhancing reproducibility of gene expression analysis with known protein functional relationships: The concept of well-associated protein by Pradines, Joël R, Farutin, Victor, Cilfone, Nicholas A, Ghavami, Abouzar, Kurtagic, Elma, Guess, Jamey, Manning, Anthony M, Capila, Ishan

“…Identification of differentially expressed genes (DEGs) is well recognized to be variable across independent replications of genome-wide transcriptional…”
Get full text

Combining measurements to estimate properties and characterization extent of complex biochemical mixtures; applications to Heparan Sulfate by Pradines, Joël R., Beccati, Daniela, Lech, Miroslaw, Ozug, Jennifer, Farutin, Victor, Huang, Yongqing, Gunay, Nur Sibel, Capila, Ishan

“…Complex mixtures of molecular species, such as glycoproteins and glycosaminoglycans, have important biological and therapeutic functions. Characterization of…”
Get full text

An integrated approach using orthogonal analytical techniques to characterize heparan sulfate structure by Beccati, Daniela, Lech, Miroslaw, Ozug, Jennifer, Gunay, Nur Sibel, Wang, Jing, Sun, Elaine Y., Pradines, Joël R, Farutin, Victor, Shriver, Zachary, Kaundinya, Ganesh V., Capila, Ishan

“…Heparan sulfate (HS), a glycosaminoglycan present on the surface of cells, has been postulated to have important roles in driving both normal and pathological…”
Get full text

Adjuvanted influenza-H1N1 vaccination reveals lymphoid signatures of age-dependent early responses and of clinical adverse events by Sobolev, Olga, Binda, Elisa, O'Farrell, Sean, Lorenc, Anna, Pradines, Joel, Huang, Yongqing, Duffner, Jay, Schulz, Reiner, Cason, John, Zambon, Maria, Malim, Michael H, Peakman, Mark, Cope, Andrew, Capila, Ishan, Kaundinya, Ganesh V, Hayday, Adrian C

“…Vaccination offers protection against infectious diseases, yet pre-existing criteria that predict vaccine efficacy or adverse events remain unknown. Hayday and…”
Get full text

Demonstration of equivalence of a generic glatiramer acetate (Glatopa™) by Anderson, James, Bell, Christine, Bishop, John, Capila, Ishan, Ganguly, Tanmoy, Glajch, Joseph, Iyer, Mani, Kaundinya, Ganesh, Lansing, Jonathan, Pradines, Joel, Prescott, James, Cohen, Bruce A, Kantor, Daniel, Sachleben, Richard

“…Abstract Glatiramer acetate (GA) has been available under the brand name Copaxone® for nearly two decades. Recently, the US Food and Drug Administration (FDA)…”
Get full text

Efficacy and tolerability of an endogenous metabolic modulator (AXA1125) in fatigue-predominant long COVID: a single-centre, double-blind, randomised controlled phase 2a pilot study by Finnigan, Lucy E.M., Cassar, Mark Philip, Koziel, Margaret James, Pradines, Joel, Lamlum, Hanan, Azer, Karim, Kirby, Dan, Montgomery, Hugh, Neubauer, Stefan, Valkovič, Ladislav, Raman, Betty

“…‘Long COVID’ describes persistent symptoms, commonly fatigue, lasting beyond 12 weeks following SARS-CoV-2 infection. Potential causes include reduced…”
Get full text

Comparative Gene Expression Profiling between a Generic (M356) and Brand Copaxone® (glatiramer acetate injection) (P1.144) by D’Alessandro, Josephine, Duffner, Jay, Pradines, Joel, Honan, Christopher, Prod’homme, Thomas, Ganguly, Tanmoy, Kaundinya, Ganesh

“…Abstract only…”
Get full text

Equivalent Gene Expression Profiles between Glatopa.sup.[TM] and Copaxone.sup. by D'Alessandro, Josephine S, Duffner, Jay, Pradines, Joel, Capila, Ishan, Garofalo, Kevin, Kaundinya, Ganesh, Greenberg, Benjamin M, Kantor, Daniel, Ganguly, Tanmoy C

“…Glatopa.sup.[TM] is a generic glatiramer acetate recently approved for the treatment of patients with relapsing forms of multiple sclerosis. Gene expression…”
Get full text

Corrigendum: adjuvanted Influenza-H1N1 vaccination reveals lymphoid signatures of age-dependent early responses and of clinical adverse events by Sobolev, Olga, Binda, Elisa, O'Farrell, Sean, Lorenc, Anna, Pradines, Joel, Huang, Yongqing, Duffner, Jay, Schulz, Reiner, Cason, John, Zambon, Maria, Malim, Michael H, Peakman, Mark, Cope, Andrew, Capila, Ishan, Kaundinya, Ganesh V, Hayday, Adrian C

Get full text

Erratum: Corrigendum: Adjuvanted influenza-H1N1 vaccination reveals lymphoid signatures of age-dependent early responses and of clinical adverse events by Sobolev, Olga, Binda, Elisa, O'Farrell, Sean, Lorenc, Anna, Pradines, Joel, Huang, Yongqing, Duffner, Jay, Schulz, Reiner, Cason, John, Zambon, Maria, Malim, Michael H, Peakman, Mark, Cope, Andrew, Capila, Ishan, Kaundinya, Ganesh V, Hayday, Adrian C

Get full text

Corrigendum: Adjuvanted influenza-H1N1 vaccination reveals lymphoid signatures of age-dependent early responses and of clinical adverse events by Sobolev, Olga, Binda, Elisa, O'Farrell, Sean, Lorenc, Anna, Pradines, Joel, Huang, Yongqing, Duffner, Jay, Schulz, Reiner, Cason, John, Zambon, Maria, Malim, Michael H, Peakman, Mark, Cope, Andrew, Capila, Ishan, Kaundinya, Ganesh V, Hayday, Adrian C

Get full text

Erratum: Corrigendum: Adjuvanted influenza-H1N1 vaccination reveals lymphoid signatures of age-dependent early responses and of clinical adverse events by Sobolev, Olga, Binda, Elisa, O'Farrell, Sean, Lorenc, Anna, Pradines, Joel, Huang, Yongqing, Duffner, Jay, Schulz, Reiner, Cason, John, Zambon, Maria, Malim, Michael H, Peakman, Mark, Cope, Andrew, Capila, Ishan, Kaundinya, Ganesh V, Hayday, Adrian C

Get full text

Correction: Corrigendum: Adjuvanted influenza-H1N1 vaccination reveals lymphoid signatures of age-dependent early responses and of clinical adverse events by Sobolev, Olga, Binda, Elisa, O'Farrell, Sean, Lorenc, Anna, Pradines, Joel, Huang, Yongqing, Duffner, Jay, Schulz, Reiner, Cason, John, Zambon, Maria, Malim, Michael H, Peakman, Mark, Cope, Andrew, Capila, Ishan, Kaundinya, Ganesh V, Hayday, Adrian C

“…Nat. Immunol. 17, 204–213 (2016); published online 4 Jan 2016; corrected after print 17 March 2016 In the version of this article initially published, the…”
Get full text

Correction: Corrigendum: Adjuvanted influenza-H1N1 vaccination reveals lymphoid signatures of age-dependent early responses and of clinical adverse events by Sobolev, Olga, Binda, Elisa, O'Farrell, Sean, Lorenc, Anna, Pradines, Joel, Huang, Yongqing, Duffner, Jay, Schulz, Reiner, Cason, John, Zambon, Maria, Malim, Michael H, Peakman, Mark, Cope, Andrew, Capila, Ishan, Kaundinya, Ganesh V, Hayday, Adrian C

“…Nat. Immunol.; doi:10.1038/ni.3328; corrected online 7 January 2016 In the version of this article initially published online, the location of Momenta…”
Get full text

The effect and mechanism of M402 on gemcitabine uptake into pancreatic tumors by Schultes, Birgit Corinna, Chu, Chia Lin, Long, Alison, Sun, Elaine, Kurtagic, Elma, Beccati, Daniela, Pradines, Joel, Miller, Paul, Ryan, David P., Flaherty, Keith, Roach, James, Kaundinya, Ganesh Venkataraman

“…Abstract only 215 Background: Pancreatic ductal adenocarcinoma (PDAC) is characterized by extensive desmoplasia, which has been attributed to high interstitial…”
Get full text

Analyzing protein lists with large networks: edge-count probabilities in random graphs with given expected degrees by Pradines, Joël R, Farutin, Victor, Rowley, Steve, Dancík, Vlado

“…We present an analytical framework to analyze lists of proteins with large undirected graphs representing their known functional relationships. We consider…”
Get more information

Edge-count probabilities for the identification of local protein communities and their organization by Farutin, Victor, Robison, Keith, Lightcap, Eric, Dancik, Vlado, Ruttenberg, Alan, Letovsky, Stanley, Pradines, Joel

“…We present a computational approach based on a local search strategy that discovers sets of proteins that preferentially interact with each other. Such sets…”
Get full text