Search Results - "Pradines, Joël R."
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Multiomic study of skin, peripheral blood, and serum: is serum proteome a reflection of disease process at the end-organ level in systemic sclerosis?
Published in Arthritis research & therapy (15-10-2021)“…Serum proteins can be readily assessed during routine clinical care. However, it is unclear to what extent serum proteins reflect the molecular dysregulations…”
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Enhancing reproducibility of gene expression analysis with known protein functional relationships: The concept of well-associated protein
Published in PLoS computational biology (14-02-2020)“…Identification of differentially expressed genes (DEGs) is well recognized to be variable across independent replications of genome-wide transcriptional…”
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Combining measurements to estimate properties and characterization extent of complex biochemical mixtures; applications to Heparan Sulfate
Published in Scientific reports (26-04-2016)“…Complex mixtures of molecular species, such as glycoproteins and glycosaminoglycans, have important biological and therapeutic functions. Characterization of…”
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An integrated approach using orthogonal analytical techniques to characterize heparan sulfate structure
Published in Glycoconjugate journal (01-02-2017)“…Heparan sulfate (HS), a glycosaminoglycan present on the surface of cells, has been postulated to have important roles in driving both normal and pathological…”
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Analyzing protein lists with large networks: edge-count probabilities in random graphs with given expected degrees
Published in Journal of computational biology (01-03-2005)“…We present an analytical framework to analyze lists of proteins with large undirected graphs representing their known functional relationships. We consider…”
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Complex ligand-protein systems: a globally convergent iterative method for the n × m case
Published in Journal of mathematical biology (01-10-2001)“…When n types of univalent ligands are competing for the binding to m types of protein sites, the determination of the system composition at equilibrium reduces…”
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Coherence resonance in excitable and oscillatory systems: the essential role of slow and fast dynamics
Published in Physical review. E, Statistical physics, plasmas, fluids, and related interdisciplinary topics (01-12-1999)“…Stochastic noise of an appropriate amplitude can maximize the coherence of the dynamics of certain types of excitable systems via a phenomenon known as…”
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