Search Results - "Pradella, Davide"

Alternative splicing in Alzheimer’s disease by Biamonti, Giuseppe, Amato, Angela, Belloni, Elisa, Di Matteo, Anna, Infantino, Lucia, Pradella, Davide, Ghigna, Claudia

“…Alzheimer’s disease (AD) is the most frequent neurodegenerative disorder in the elderly, occurring in approximately 20% of people older than 80. The molecular…”
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A ligand-insensitive UNC5B splicing isoform regulates angiogenesis by promoting apoptosis by Pradella, Davide, Deflorian, Gianluca, Pezzotta, Alex, Di Matteo, Anna, Belloni, Elisa, Campolungo, Daniele, Paradisi, Andrea, Bugatti, Mattia, Vermi, William, Campioni, Matteo, Chiapparino, Antonella, Scietti, Luigi, Forneris, Federico, Giampietro, Costanza, Volf, Nina, Rehman, Michael, Zacchigna, Serena, Paronetto, Maria Paola, Pistocchi, Anna, Eichmann, Anne, Mehlen, Patrick, Ghigna, Claudia

“…The Netrin-1 receptor UNC5B is an axon guidance regulator that is also expressed in endothelial cells (ECs), where it finely controls developmental and tumor…”
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SAM68: Signal Transduction and RNA Metabolism in Human Cancer by Ghigna, Claudia, Belloni, Elisa, Di Matteo, Anna, Pradella, Davide, Frisone, Paola, Paronetto, Maria Paola

“…Alterations in expression and/or activity of splicing factors as well as mutations in cis-actingsplicing regulatory sequences contribute to cancer phenotypes…”
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Alternative splicing in endothelial cells: novel therapeutic opportunities in cancer angiogenesis by Di Matteo, Anna, Belloni, Elisa, Pradella, Davide, Cappelletto, Ambra, Volf, Nina, Zacchigna, Serena, Ghigna, Claudia

“…Abstract Alternative splicing (AS) is a pervasive molecular process generating multiple protein isoforms, from a single gene. It plays fundamental roles during…”
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Alternative Splicing Changes Promoted by NOVA2 Upregulation in Endothelial Cells and Relevance for Gastric Cancer by Di Matteo, Anna, Belloni, Elisa, Pradella, Davide, Chiaravalli, Anna Maria, Pini, Giacomo Maria, Bugatti, Mattia, Alfieri, Roberta, Barzan, Chiara, Franganillo Tena, Elena, Bione, Silvia, Terenzani, Elisa, Sessa, Fausto, Wyatt, Christopher D R, Vermi, William, Ghigna, Claudia

“…Angiogenesis is crucial for cancer progression. While several anti-angiogenic drugs are in use for cancer treatment, their clinical benefits are…”
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Widespread Alternative Splicing Changes in Metastatic Breast Cancer Cells by Oh, Jagyeong, Pradella, Davide, Shao, Changwei, Li, Hairi, Choi, Namjeong, Ha, Jiyeon, Ruggiero, Sonia, Fu, Xiang-Dong, Zheng, Xuexiu, Ghigna, Claudia, Shen, Haihong

“…Aberrant alternative splicing (AS) is a hallmark of cancer and a potential target for novel anti-cancer therapeutics. Breast cancer-associated AS events are…”
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SRSF9 Regulates Cassette Exon Splicing of Caspase-2 by Interacting with Its Downstream Exon by Ha, Jiyeon, Jang, Hana, Choi, Namjeong, Oh, Jagyeong, Min, Chanhyuk, Pradella, Davide, Jung, Da-Woon, Williams, Darren R, Park, Daeho, Ghigna, Claudia, Zheng, Xuexiu, Shen, Haihong

“…Alternative splicing (AS) is an important posttranscriptional regulatory process. Damaged or unnecessary cells need to be removed though apoptosis to maintain…”
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EMT and stemness: flexible processes tuned by alternative splicing in development and cancer progression by Pradella, Davide, Naro, Chiara, Sette, Claudio, Ghigna, Claudia

“…Epithelial-to-mesenchymal transition (EMT) is associated with metastasis formation as well as with generation and maintenance of cancer stem cells. In this…”
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Opposite Roles of Tra2β and SRSF9 in the v10 Exon Splicing of CD44 by Oh, Jagyeong, Liu, Yongchao, Choi, Namjeong, Ha, Jiyeon, Pradella, Davide, Ghigna, Claudia, Zheng, Xuexiu, Shen, Haihong

“…CD44 is a transmembrane glycoprotein involved in cell–cell and cell–matrix interactions. Several CD44 protein isoforms are generated in human through…”
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The alternative splicing factor Nova2 regulates vascular development and lumen formation by Giampietro, Costanza, Deflorian, Gianluca, Gallo, Stefania, Di Matteo, Anna, Pradella, Davide, Bonomi, Serena, Belloni, Elisa, Nyqvist, Daniel, Quaranta, Valeria, Confalonieri, Stefano, Bertalot, Giovanni, Orsenigo, Fabrizio, Pisati, Federica, Ferrero, Elisabetta, Biamonti, Giuseppe, Fredrickx, Evelien, Taveggia, Carla, Wyatt, Chris D. R., Irimia, Manuel, Di Fiore, Pier Paolo, Blencowe, Benjamin J., Dejana, Elisabetta, Ghigna, Claudia

“…Vascular lumen formation is a fundamental step during angiogenesis; yet, the molecular mechanisms underlying this process are poorly understood. Recent studies…”
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Global Alternative Splicing Defects in Human Breast Cancer Cells by Oh, Jagyeong, Pradella, Davide, Kim, Yoonseong, Shao, Changwei, Li, Hairi, Choi, Namjeong, Ha, Jiyeon, Di Matteo, Anna, Fu, Xiang-Dong, Zheng, Xuexiu, Ghigna, Claudia, Shen, Haihong

“…Breast cancer is the most frequently occurred cancer type and the second cause of death in women worldwide. Alternative splicing (AS) is the process that…”
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Gene Expression Profiles Controlled by the Alternative Splicing Factor Nova2 in Endothelial Cells by Belloni, Elisa, Di Matteo, Anna, Pradella, Davide, Vacca, Margherita, Wyatt, Christopher D R, Alfieri, Roberta, Maffia, Antonio, Sabbioneda, Simone, Ghigna, Claudia

“…Alternative splicing (AS) plays an important role in expanding the complexity of the human genome through the production of specialized proteins regulating…”
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