Search Results - "Pradel, Lydie"

Peripheral blood NK cells from breast cancer patients are tumor-induced composite subsets by Mamessier, Emilie, Pradel, Lydie C, Thibult, Marie-Laure, Drevet, Charlotte, Zouine, Atika, Jacquemier, Jocelyne, Houvenaeghel, Gilles, Bertucci, François, Birnbaum, Daniel, Olive, Daniel

“…Human NK lymphocytes are involved in antitumor immunity. The therapeutic potential of this population against cancers has stimulated their study and led to the…”
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Transcriptional Response in a Sepsis Mouse Model Reflects Transcriptional Response in Sepsis Patients by Rosier, Florian, Nuñez, Nicolas Fernandez, Torres, Magali, Loriod, Béatrice, Rihet, Pascal, Pradel, Lydie C

“…Mortality due to sepsis remains unacceptably high, especially for septic shock patients. Murine models have been used to better understand pathophysiology…”
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Genetic Predisposition to the Mortality in Septic Shock Patients: From GWAS to the Identification of a Regulatory Variant Modulating the Activity of a CISH Enhancer by Rosier, Florian, Brisebarre, Audrey, Dupuis, Claire, Baaklini, Sabrina, Puthier, Denis, Brun, Christine, Pradel, Lydie C., Rihet, Pascal, Payen, Didier

“…The high mortality rate in septic shock patients is likely due to environmental and genetic factors, which influence the host response to infection. Two…”
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Site- and allele-specific polycomb dysregulation in T-cell leukaemia by Navarro, Jean-Marc, Touzart, Aurore, Pradel, Lydie C., Loosveld, Marie, Koubi, Myriam, Fenouil, Romain, Le Noir, Sandrine, Maqbool, Muhammad Ahmad, Morgado, Ester, Gregoire, Claude, Jaeger, Sebastien, Mamessier, Emilie, Pignon, Charles, Hacein-Bey-Abina, Salima, Malissen, Bernard, Gut, Marta, Gut, Ivo G., Dombret, Hervé, Macintyre, Elizabeth A., Howe, Steven J., Gaspar, H. Bobby, Thrasher, Adrian J., Ifrah, Norbert, Payet-Bornet, Dominique, Duprez, Estelle, Andrau, Jean-Christophe, Asnafi, Vahid, Nadel, Bertrand

“…T-cell acute lymphoblastic leukaemias (T-ALL) are aggressive malignant proliferations characterized by high relapse rates and great genetic heterogeneity. TAL1…”
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Technical Advance: Autofluorescence as a tool for myeloid cell analysis by Mitchell, Andrew J., Pradel, Lydie C., Chasson, Lionel, Van Rooijen, Nico, Grau, Georges E., Hunt, Nicholas H., Chimini, Giovanna

“…The autofluorescence of myeloid cell populations is heterogeneous and can be used as a tool for identification and phenotyping of myeloid subsets. Cellular AF…”
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Recent advances in high-throughput approaches to dissect enhancer function [version 1; peer review: 3 approved] by Santiago-Algarra, David, Dao, Lan T.M, Pradel, Lydie, España, Alexandre, Spicuglia, Salvatore

“…The regulation of gene transcription in higher eukaryotes is accomplished through the involvement of transcription start site (TSS)-proximal (promoters) and…”
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A critical regulator of Bcl2 revealed by systematic transcript discovery of lncRNAs associated with T-cell differentiation by Saadi, Wiam, Kermezli, Yasmina, Dao, Lan T. M., Mathieu, Evelyne, Santiago-Algarra, David, Manosalva, Iris, Torres, Magali, Belhocine, Mohamed, Pradel, Lydie, Loriod, Beatrice, Aribi, Mourad, Puthier, Denis, Spicuglia, Salvatore

“…Normal T-cell differentiation requires a complex regulatory network which supports a series of maturation steps, including lineage commitment, T-cell receptor…”
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Beyond genome-wide scan: Association of a cis-regulatory NCR3 variant with mild malaria in a population living in the Republic of Congo by Baaklini, Sabrina, Afridi, Sarwat, Nguyen, Thy Ngoc, Koukouikila-Koussounda, Felix, Ndounga, Mathieu, Imbert, Jean, Torres, Magali, Pradel, Lydie, Ntoumi, Francine, Rihet, Pascal

“…Linkage studies have revealed a linkage of mild malaria to chromosome 6p21 that contains the NCR3 gene encoding a natural killer cell receptor, whereas…”
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NIMA-related kinase TbNRKC is involved in basal body separation in Trypanosoma brucei by Pradel, Lydie C, Bonhivers, Mélanie, Landrein, Nicolas, Robinson, Derrick R

“…The NIMA-related kinase 2 (NEK 2) has important cell cycle functions related to centriole integrity and splitting. Trypanosoma brucei does not possess…”
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ATP-binding cassette transporter hallmarks tissue macrophages and modulates cytokine-triggered polarization programs by Pradel, Lydie C, Mitchell, Andrew J, Zarubica, Ana, Dufort, Laetitia, Chasson, Lionel, Naquet, Philippe, Broccardo, Cyril, Chimini, Giovanna

“…Macrophages are central players in both lipid metabolism and innate immunity. Their determinant role in the pathogenesis of atherosclerosis is under the…”
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The European Blueprint project: towards a full epigenome characterization of the immune system by Pradel, Lydie C, Vanhille, Laurent, Spicuglia, Salvatore

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The Membrane Skeleton in Paramecium: Molecular Characterization of a Novel Epiplasmin Family and Preliminary GFP Expression Results by Pomel, Sébastien, Diogon, Marie, Bouchard, Philippe, Pradel, Lydie, Ravet, Viviane, Coffe, Gérard, Viguès, Bernard

“…Previous attempts to identify the membrane skeleton of Paramecium cells have revealed a protein pattern that is both complex and specific. The most prominent…”
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Dynamics of broad H3K4me3 domains uncover an epigenetic switch between cell identity and cancer-related genes by Belhocine, Mohamed, Simonin, Mathieu, Abad Flores, José David, Cieslak, Agata, Manosalva, Iris, Pradel, Lydie, Smith, Charlotte, Mathieu, Eve-Lyne, Charbonnier, Guillaume, Martens, Joost H A, Stunnenberg, Hendrik G, Maqbool, Muhammad Ahmad, Mikulasova, Aneta, Russell, Lisa J, Rico, Daniel, Puthier, Denis, Ferrier, Pierre, Asnafi, Vahid, Spicuglia, Salvatore

“…Broad domains of H3K4 methylation have been associated with consistent expression of tissue-specific, cell identity, and tumor suppressor genes. Here, we…”
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Association of a functional TNF variant with Plasmodium falciparum parasitaemia in a congolese population by Pradel, Lydie, Nguyen, T, Baaklini, S, Koukouikila-Koussounda, F, Ndounga, M, Torres, M, Ntoumi, F, Rihet, P

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High-throughput approaches to study cis-regulating elements by España, Alexandre P, Santiago-Algarra, David, Pradel, Lydie, Spicuglia, Salvatore

“…Gene expression in higher eukaryotes is regulated through the involvement of transcription start site (TSS)-proximal (promoters) and -distal (enhancers)…”
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Approaches combining mice and Drosophila melanogaster models to decipher human sepsis by Ramy, R, Garnier, S, Pradel, L, Röder, L, Loriod, B, Defaye, A, Perrin, L, Rihet, P, Nguyen, C

“…Keywords: Oleic Acid, Peripheral Blood Mononuclear Cell, Reference Panel, Sterile Inflammation, Complex Biological Process…”
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NIMA-related kinase Tb NRKC is involved in basal body separation in Trypanosoma brucei by Pradel, Lydie C., Bonhivers, Mélanie, Landrein, Nicolas, Robinson, Derrick R.

“…The NIMA-related kinase 2 (NEK 2) has important cell cycle functions related to centriole integrity and splitting. Trypanosoma brucei does not possess…”
Get full text