Search Results - "Prada, Patrı́cia O"

Loss-of-Function Mutation in Toll-Like Receptor 4 Prevents Diet-Induced Obesity and Insulin Resistance by TSUKUMO, Daniela M. L, CARVALHO-FILHO, Marco A, SAAD, Mario J. A, CARVALHEIRA, José B. C, PRADA, Patricia O, HIRABARA, Sandro M, SCHENKA, André A, ARAUJO, Eliana P, VASSALLO, José, CURI, Rui, VELLOSO, Licio A

“…Loss-of-Function Mutation in Toll-Like Receptor 4 Prevents Diet-Induced Obesity and Insulin Resistance Daniela M.L. Tsukumo 1 , Marco A. Carvalho-Filho 1 ,…”
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Probiotics modulate gut microbiota and improve insulin sensitivity in DIO mice by Bagarolli, Renata A., Tobar, Natália, Oliveira, Alexandre G., Araújo, Tiago G., Carvalho, Bruno M., Rocha, Guilherme Z., Vecina, Juliana F., Calisto, Kelly, Guadagnini, Dioze, Prada, Patrícia O., Santos, Andrey, Saad, Sara T.O., Saad, Mario J.A.

“…Obesity and type 2 diabetes are characterized by subclinical inflammatory process. Changes in composition or modulation of the gut microbiota may play an…”
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Gut microbiota is a key modulator of insulin resistance in TLR 2 knockout mice by Caricilli, Andréa M, Picardi, Paty K, de Abreu, Lélia L, Ueno, Mirian, Prada, Patrícia O, Ropelle, Eduardo R, Hirabara, Sandro Massao, Castoldi, Ângela, Vieira, Pedro, Camara, Niels O S, Curi, Rui, Carvalheira, José B, Saad, Mário J A

“…Environmental factors and host genetics interact to control the gut microbiota, which may have a role in the development of obesity and insulin resistance…”
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Inhibition of Hypothalamic Inflammation Reverses Diet-Induced Insulin Resistance in the Liver by MILANSKI, Marciane, ARRUDA, Ana P, PRADA, Patricia O, SAAD, Mario J, VELLOSO, Licio A, COOPE, Andressa, IGNACIO-SOUZA, Leticia M, NUNEZ, Carla E, ROMAN, Erika A, ROMANATTO, Talita, PASCOAL, Livia B, CARICILLI, Andrea M, TORSONI, Marcio A

“…Defective liver gluconeogenesis is the main mechanism leading to fasting hyperglycemia in type 2 diabetes, and, in concert with steatosis, it is the hallmark…”
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IL-6 and IL-10 Anti-Inflammatory Activity Links Exercise to Hypothalamic Insulin and Leptin Sensitivity through IKKβ and ER Stress Inhibition by Ropelle, Eduardo R, Flores, Marcelo B, Cintra, Dennys E, Rocha, Guilherme Z, Pauli, Jose R, Morari, Joseane, de Souza, Claudio T, Moraes, Juliana C, Prada, Patricia O, Guadagnini, Dioze, Marin, Rodrigo M, Oliveira, Alexandre G, Augusto, Taize M, Carvalho, Hernandes F, Velloso, Licio A, Saad, Mario J.A, Carvalheira, Jose B.C

“…Overnutrition caused by overeating is associated with insulin and leptin resistance through IKKβ activation and endoplasmic reticulum (ER) stress in the…”
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Exercise alters the mitochondrial proteostasis and induces the mitonuclear imbalance and UPRmt in the hypothalamus of mice by Braga, Renata R., Crisol, Barbara M., Brícola, Rafael S., Sant’ana, Marcella R., Nakandakari, Susana C. B. R., Costa, Suleyma O., Prada, Patrícia O., da Silva, Adelino S. R., Moura, Leandro P., Pauli, José R., Cintra, Dennys E., Ropelle, Eduardo R.

“…The maintenance of mitochondrial activity in hypothalamic neurons is determinant to the control of energy homeostasis in mammals. Disturbs in the mitochondrial…”
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Diacerhein Improves Glucose Tolerance and Insulin Sensitivity in Mice on a High-Fat Diet by Tobar, Natália, Oliveira, Alexandre G, Guadagnini, Dioze, Bagarolli, Renata A, Rocha, Guilherme Z, Araújo, Tiago G, Santos-Silva, Junia C, Zollner, Ricardo L, Boechat, Luiz H. B, Carvalheira, José B. C, Prada, Patrícia O, Saad, Mario J. A

“…Obesity and type 2 diabetes are characterized by insulin resistance, and the common basis of these events is a chronic and systemic inflammatory process marked…”
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Hypothalamic S1P/S1PR1 axis controls energy homeostasis by Silva, Vagner R. R., Micheletti, Thayana O., Pimentel, Gustavo D., Katashima, Carlos K., Lenhare, Luciene, Morari, Joseane, Mendes, Maria Carolina S., Razolli, Daniela S., Rocha, Guilherme Z., de Souza, Claudio T., Ryu, Dongryeol, Prada, Patrícia O., Velloso, Lício A., Carvalheira, José B. C., Rodrigo Pauli, José, Cintra, Dennys E., Ropelle, Eduardo R.

“…Sphingosine 1-phosphate receptor 1 (S1PR1) is a G-protein-coupled receptor for sphingosine-1-phosphate (S1P) that has a role in many physiological and…”
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Identification of intracellular peptides in rat adipose tissue: Insights into insulin resistance by Berti, Denise A., Russo, Lilian C., Castro, Leandro M., Cruz, Lilian, Gozzo, Fábio C., Heimann, Joel C., Lima, Fabio B., Oliveira, Ariclécio C., Andreotti, Sandra, Prada, Patrícia O., Heimann, Andrea S., Ferro, Emer S.

“…Intracellular peptides generated by the proteasome and oligopeptidases have been suggested to function in signal transduction and to improve insulin resistance…”
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Tub Has a Key Role in Insulin and Leptin Signaling and Action In Vivo in Hypothalamic Nuclei by PRADA, Patricia O, QUARESMA, Paula G. F, SAAD, Mario J. A, CARICILLI, Andrea M, SANTOS, Andressa C, GUADAGNINI, Dioze, MORARI, Joseane, WEISSMANN, Lais, ROPELLE, Eduardo R, CARVALHEIRA, José Barreto C, VELLOSO, Licio A

“…Mutation of tub gene in mice induces obesity, suggesting that tub could be an important regulator of energy balance. In the current study, we investigated…”
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Acute exercise suppresses hypothalamic PTP1B protein level and improves insulin and leptin signaling in obese rats by Chiarreotto-Ropelle, Eloize C, Pauli, Luciana S S, Katashima, Carlos K, Pimentel, Gustavo D, Picardi, Paty K, Silva, Vagner R R, de Souza, Claudio T, Prada, Patrícia O, Cintra, Dennys E, Carvalheira, José B C, Ropelle, Eduardo R, Pauli, José R

“…Hypothalamic inflammation is associated with insulin and leptin resistance, hyperphagia, and obesity. In this scenario, hypothalamic protein tyrosine…”
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Defective Insulin and Acetylcholine Induction of Endothelial Cell–Nitric Oxide Synthase Through Insulin Receptor Substrate/Akt Signaling Pathway in Aorta of Obese Rats by ZECCHIN, Henrique G, PRIVIERO, Fernanda B. M, SOUZA, Claudio T, ZECCHIN, Karina G, PRADO, Patricia O, CARVALHEIRA, José B. C, VELLOSO, Licio A, ANTUNES, Edson, SAAD, Mario J. A

“…Defective Insulin and Acetylcholine Induction of Endothelial Cell–Nitric Oxide Synthase Through Insulin Receptor Substrate/Akt Signaling Pathway in Aorta of…”
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Reversal of diet-induced insulin resistance with a single bout of exercise in the rat: the role of PTP1B and IRS-1 serine phosphorylation by Ropelle, Eduardo R., Pauli, José R., Prada, Patrícia O., De Souza, Cláudio T., Picardi, Paty K., Faria, Marcel C., Cintra, Dennys E., Fernandes, Maria Fernanda de A., Flores, Marcelo B., Velloso, Lício A., Saad, Mario J. A., Carvalheira, José B. C.

“…Lifestyle interventions including exercise programmes are cornerstones in the prevention of obesity-related diabetes. In this study, we demonstrate that a…”
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PAFR in adipose tissue macrophages is associated with anti-inflammatory phenotype and metabolic homoeostasis by Filgueiras, Luciano Ribeiro, Koga, Marianna Mainardi, Quaresma, Paula G, Ishizuka, Edson Kiyotaka, Montes, Marlise B A, Prada, Patricia O, Saad, Mario J, Jancar, Sonia, Rios, Francisco J

“…Metabolic dysfunction is associated with adipose tissue inflammation and macrophage infiltration. PAFR (platelet-activating factor receptor) is expressed in…”
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Blocking iNOS and endoplasmic reticulum stress synergistically improves insulin resistance in mice by Zanotto, Tamires M, Quaresma, Paula G.F, Guadagnini, Dioze, Weissmann, Lais, Santos, Andressa C, Vecina, Juliana F, Calisto, Kelly, Santos, Andrey, Prada, Patrícia O, Saad, Mario J.A

“…Abstract Objective Recent data show that iNOS has an essential role in ER stress in obesity. However, whether iNOS is sufficient to account for obesity-induced…”
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EGFR Tyrosine Kinase Inhibitor (PD153035) Improves Glucose Tolerance and Insulin Action in High-Fat Diet–Fed Mice by PRADA, Patricia O, ROPELLE, Eduardo R, VASSALLO, José, VELLOSO, Licio A, CARVALHEIRA, José B, SAAD, Mario J. A, MOURAO, Rosa H, DE SOUZA, Claudio T, PAULI, Jose R, CINTRA, Dennys E, SCHENKA, André, ROCCO, Silvana A, RITTNER, Roberto, FRANCHINI, Kleber G

“…EGFR Tyrosine Kinase Inhibitor (PD153035) Improves Glucose Tolerance and Insulin Action in High-Fat Diet–Fed Mice Patricia O. Prada 1 , Eduardo R. Ropelle 1 ,…”
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Retraction: Gut Microbiota Is a Key Modulator of Insulin Resistance in TLR 2 Knockout Mice by Caricilli, Andréa M, Picardi, Paty K, de Abreu, Lélia L, Ueno, Mirian, Prada, Patrícia O, Ropelle, Eduardo R, Hirabara, Sandro Massao, Castoldi, Ângela, Vieira, Pedro, Camara, Niels O S, Curi, Rui, Carvalheira, José B, Saad, Mário J A

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Citrate diminishes hypothalamic acetyl-CoA carboxylase phosphorylation and modulates satiety signals and hepatic mechanisms involved in glucose homeostasis in rats by Cesquini, Maristela, Stoppa, Graziela R., Prada, Patrícia O., Torsoni, Adriana S., Romanatto, Talita, Souza, Alex, Saad, Mario J., Velloso, Licio A., Torsoni, Marcio A.

“…The hypothalamic AMP-activated protein kinase (AMPK)/acetyl-CoA carboxylase (ACC) pathway is known to play an important role in the control of food intake and…”
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Intracerebroventricular injection of citrate inhibits hypothalamic AMPK and modulates feeding behavior and peripheral insulin signaling by Stoppa, Graziela R, Cesquini, Maristela, Roman, Erika A, Prada, Patrícia O, Torsoni, Adriana S, Romanatto, Talita, Saad, Mario J, Velloso, Licio A, Torsoni, Marcio A

“…We hypothesized that citrate might modulate the AMP-activated protein kinase/acetyl-CoA carboxylase (AMPK)/(ACC) pathway and participate in neuronal feeding…”
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Growth hormone enhances the recovery of hypoglycemia via ventromedial hypothalamic neurons by Furigo, Isadora C., Souza, Gabriel O., Teixeira, Pryscila D. S., Guadagnini, Dioze, Frazão, Renata, List, Edward O., Kopchick, John J., Prada, Patricia O., Jr, Jose Donato

“…Growth hormone (GH) is secreted during hypoglycemia, and GH‐responsive neurons are found in brain areas containing glucose‐sensing neurons that regulate the…”
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