Search Results - "Pradère, U"
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Site-specific conjugation of drug-like fragments to an antimiR scaffold as a strategy to target miRNAs inside RISC
Published in Chemical communications (Cambridge, England) (01-01-2016)“…We synthesized a miR-122 antimiR library in which drug-like fragments were site-specifically introduced to short 2'-O-methyl-RNAs. At some sites selected…”
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Substrate mimicry: HIV-1 reverse transcriptase recognizes 6-modified-3′-azido-2′,3′-dideoxyguanosine-5′-triphosphates as adenosine analogs
Published in Nucleic acids research (01-01-2012)“…β-D-3′-Azido-2′,3′-dideoxyguanosine (3′-azido-ddG) is a potent inhibitor of HIV-1 replication with a superior resistance profile to zidovudine. Recently, we…”
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