Search Results - "Prabu Paramasivam"

Linking a role of lncRNAs (long non-coding RNAs) with insulin resistance, accelerated senescence, and inflammation in patients with type 2 diabetes by Sathishkumar, Chandrakumar, Prabu, Paramasivam, Mohan, Viswanathan, Balasubramanyam, Muthuswamy

“…Studying epigenetics is expected to provide precious information on how environmental factors contribute to type 2 diabetes mellitus (T2DM) at the genomic…”
Get full text

Impairment of neuronal tyrosine phosphatase STEP worsens post-ischemic inflammation and brain injury under hypertensive condition by Paramasivam, Prabu, Choi, Seong Won, Poddar, Ranjana, Paul, Surojit

“…Hypertension is associated with poor outcome and higher mortality in patients with ischemic stroke. The impairment of adaptive vascular mechanisms under…”
Get full text

Improvement in glucose tolerance and insulin sensitivity by probiotic strains of Indian gut origin in high-fat diet-fed C57BL/6J mice by Balakumar, Mahalingam, Prabhu, Durai, Sathishkumar, Chandrakumar, Prabu, Paramasivam, Rokana, Namita, Kumar, Ramesh, Raghavan, Srividhya, Soundarajan, Avinash, Grover, Sunita, Batish, Virender Kumar, Mohan, Viswanathan, Balasubramanyam, Muthuswamy

“…Purpose Diabetes and obesity are characterized by glucose intolerance, fat deposition, inflammation, and dyslipidemia. Recent reports postulated that distinct…”
Get full text

Genetic Exchange of Lung-Derived Exosome to Brain Causing Neuronal Changes on COVID-19 Infection by Ahmed, Shiek S. S. J., Paramasivam, Prabu, Kamath, Manjunath, Sharma, Ashutosh, Rome, Sophie, Murugesan, Ram

“…The pandemic of novel coronavirus 2 (SARS-CoV-2) has made global chaos for normal human living. Despite common COVID-19 symptoms, variability in clinical…”
Get full text

Altered circulatory levels of miR-128, BDNF, cortisol and shortened telomeres in patients with type 2 diabetes and depression by Prabu, Paramasivam, Poongothai, Subramani, Shanthirani, Coimbatore Subramanian, Anjana, Ranjit Mohan, Mohan, Viswanathan, Balasubramanyam, Muthuswamy

“…Aims Several studies have reported the role of biomarkers either in diabetes or depression. The present study is aimed at profiling the circulating levels of…”
Get full text

Circulating MiRNAs of 'Asian Indian Phenotype' Identified in Subjects with Impaired Glucose Tolerance and Patients with Type 2 Diabetes by Prabu, Paramasivam, Rome, Sophie, Sathishkumar, Chandrakumar, Aravind, Sankaramoorthy, Mahalingam, Balakumar, Shanthirani, Coimbatore Subramanian, Gastebois, Caroline, Villard, Audrey, Mohan, Viswanathan, Balasubramanyam, Muthuswamy

“…Several omics technologies are underway worldwide with an aim to unravel the pathophysiology of a complex phenotype such as type 2 diabetes mellitus (T2DM)…”
Get full text

Regulatory Cross Talk Between SARS-CoV-2 Receptor Binding and Replication Machinery in the Human Host by Ahmed, Shiek S. S. J., Paramasivam, Prabu, Raj, Kamal, Kumar, Vishal, Murugesan, Ram, Ramakrishnan, V.

“…We dissect the mechanism of SARS-CoV-2 in human lung host from the initial phase of receptor binding to viral replication machinery. Two independent lung…”
Get full text

Clinical utility of brain-derived neurotrophic factor as a biomarker with left ventricular echocardiographic indices for potential diagnosis of coronary artery disease by Monisha, K. G., Prabu, Paramasivam, Chokkalingam, M., Murugesan, Ram, Milenkovic, Dragan, Ahmed, Shiek S. S. J.

“…Brain-derived neurotrophic factor (BDNF) plays a central pivotal role in the development of the cardiovascular system. Recent evidence suggests that BDNF has…”
Get full text

Correction: Blood-derived miRNA levels are not correlated with metabolic or anthropometric parameters in obese pre-diabetic subjects but with systemic inflammation by Paramasivam, Prabu, Meugnier, Emmanuelle, Gokulakrishnan, Kuppan, Ranjani, Harish, Staimez, Lisa R, Weber, Mary Beth, Narayan, K. M. Venkat, Vidal, Hubert, Tandon, Nikhil, Prabhakaran, Dorairaj, Anjana, Ranjit Mohan, Mohan, Viswanathan, Rome, Sophie, Balasubramanyam, Muthuswamy

Get full text

Blood-derived miRNA levels are not correlated with metabolic or anthropometric parameters in obese pre-diabetic subjects but with systemic inflammation by Paramasivam, Prabu, Meugnier, Emmanuelle, Gokulakrishnan, Kuppan, Ranjini, Harish, Staimez, Lisa R, Weber, Mary Beth, Narayan, K M Venkat, Vidal, Hubert, Tandon, Nikhil, Prabhakaran, Dorairaj, Mohan, Anjana Ranjit, Mohan, Viswanathan, Rome, Sophie, Balasubramanyam, Muthuswamy

“…As blood-derived miRNAs (c-miRNAs) are modulated by exercise and nutrition, we postulated that they might be used to monitor the effects of a lifestyle…”
Get full text

RPL6: A Key Molecule Regulating Zinc- and Magnesium-Bound Metalloproteins of Parkinson's Disease by Anirudhan, Athira, Angulo-Bejarano, Paola Isabel, Paramasivam, Prabu, Manokaran, Kalaivani, Kamath, S Manjunath, Murugesan, Ram, Sharma, Ashutosh, Ahmed, Shiek S S J

“…Parkinson's disease (PD) is a progressive neurodegenerative disease with no definite molecular markers for diagnosis. Metal exposure may alter cellular…”
Get full text

Plausible diagnostic value of urinary isomeric dimethylarginine ratio for diabetic nephropathy by Parmar, Dharmeshkumar, Bhattacharya, Nivedita, Kannan, Shanthini, Vadivel, Sangeetha, Pandey, Gautam Kumar, Ghanate, Avinash, Ragi, Nagarjuna Chary, Prabu, Paramasivam, Pramodkumar, Thyparambil Aravindakshan, Manickam, Nagaraj, Mohan, Viswanathan, Sripadi, Prabhakar, Kuppan, Gokulakrishnan, Panchagnula, Venkateswarlu

“…Altered circulatory asymmetric and symmetric dimethylarginines have been independently reported in patients with end-stage renal failure suggesting their…”
Get full text

Interdependence of metals and its binding proteins in Parkinson’s disease for diagnosis by Anirudhan, Athira, Prabu, Paramasivam, Sanyal, Jaya, Banerjee, Tapas Kumar, Guha, Gautam, Murugesan, Ram, Ahmed, Shiek S. S. J.

“…Metalloproteins utilizes cellular metals which plays a crucial function in brain that linked with neurodegenerative disorders. Parkinson’s disease (PD) is a…”
Get full text

Accelerated fat cell aging links oxidative stress and insulin resistance in adipocytes by Monickaraj, Finny, Aravind, Sankaramoorthy, Nandhini, Pichamoorthy, Prabu, Paramasivam, Sathishkumar, Chandrakumar, Mohan, Viswanathan, Balasubramanyam, Muthuswamy

“…Telomere shortening is emerging as a biological indicator of accelerated aging and aging-related diseases including type 2 diabetes. While telomere length…”
Get full text

Oxidative stress and female reproductive disorder: A review by Kalaivani Manokaran, Pavithra Bhat, Deepak Nayak, Ravisankar Baskaran, Prabu Paramasivam, Shiek Fareeth Ahmed, Keerthi Priya, Karkala Sreedhara Ranganath Pai, Vignesh E Balaji

“…Oxidative stress arises from an imbalance between the body’s pro-oxidants and antioxidants. Recently, oxidative stress has been proven a contributing factor to…”
Get full text

Screening of Crucial Cytosolicproteins Interconnecting the Endoplasmic Reticulum and Mitochondria in Parkinson’s Disease and the Impact of Anti-Parkinson Drugs in the Preservation of Organelle Connectivity by Anirudhan, Athira, Mahema, S, Ahmad, Sheikh F, Emran, Talha Bin, Ahmed, Shiek S. S. J, Paramasivam, Prabu

“…Mitochondrial dysfunction is well-established in Parkinson’s disease (PD); however, its dysfunctions associating with cell organelle connectivity remain…”
Get full text

Eleven Crucial Pesticides Appear to Regulate Key Genes That Link MPTP Mechanism to Cause Parkinson's Disease through the Selective Degeneration of Dopamine Neurons by Anirudhan, Athira, Mattethra, George Chandy, Alzahrani, Khalid J, Banjer, Hamsa Jameel, Alzahrani, Fuad M, Halawani, Ibrahim F, Patil, Shankargouda, Sharma, Ashutosh, Paramasivam, Prabu, Ahmed, Shiek S S J

“…Pesticides kill neurons, but the mechanism leading to selective dopaminergic loss in Parkinson's disease (PD) is unknown. Understanding the pesticide's effect…”
Get full text

Elucidating the Histone Deacetylase Gene Expression Signatures in Peripheral Blood Mononuclear Cells That Correlate Essential Cardiac Function and Aid in Classifying Coronary Artery Disease through a Logistic Regression Model by Monisha, K, Mahema, S, Chokkalingam, M, Ahmad, Sheikh F, Emran, Talha Bin, Prabu, Paramasivam, Ahmed, Shiek S. S. J

“…A proinflammatory role of HDACs has been implicated in the pathogenesis of atherosclerosis as an emerging novel epigenetic diagnostic biomarker. However, its…”
Get full text

Abstract WP322: GluN2A-NMDAR Mediated Increased Neuronal Prostaglandin E2 Release and Microglial Activation Exacerbates Ischemic Brain Injury Under Hyperhomocysteinemic Condition by Seelig, Sarah, Paramasivam, Prabu, Paul, Surojit, Poddar, Ranjana

“…Abstract only Hyperhomocysteinemia (Hhcy), a metabolic disorder is recognized as a risk factor for ischemic stroke. However, the impact of Hhcy on stroke…”
Get full text

Novel insights of elevated systemic levels of bisphenol-A (BPA) linked to poor glycemic control, accelerated cellular senescence and insulin resistance in patients with type 2 diabetes by Soundararajan, Avinash, Prabu, Paramasivam, Mohan, Viswanathan, Gibert, Yann, Balasubramanyam, Muthuswamy

“…There is a striking interaction of genes and environment in the etiology of type 2 diabetes mellitus (T2DM). While endocrine disrupting chemicals (EDCs) like…”
Get full text