Search Results - "Prabhudesai, Leena"

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  1. 1
    Overexpression of Glutamate-Cysteine Ligase Extends Life Span in Drosophila melanogaster

    Overexpression of Glutamate-Cysteine Ligase Extends Life Span in Drosophila melanogaster by Orr, William C., Radyuk, Svetlana N., Prabhudesai, Leena, Toroser, Dikran, Benes, Judith J., Luchak, James M., Mockett, Robin J., Rebrin, Igor, Hubbard, J. Gregory, Sohal, Rajindar S.

    Published in The Journal of biological chemistry (11-11-2005)
    “…The hypothesis that overexpression of glutamate-cysteine ligase (GCL), which catalyzes the rate-limiting reaction in de novo glutathione biosynthesis, could…”
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  2. 2
    Modulating Longevity in Drosophila by Over- and Underexpression of Glutamate-Cysteine Ligase

    Modulating Longevity in Drosophila by Over- and Underexpression of Glutamate-Cysteine Ligase by LUCHAK, JAMES M., PRABHUDESAI, LEENA, SOHAL, RAJINDAR S., RADYUK, SVETLANA N., ORR, WILLIAM C.

    Published in Annals of the New York Academy of Sciences (01-11-2007)
    “…:  A notable extension of life span (up to 50%) was achieved in Drosophila melanogaster when the catalytic subunit of glutamate‐cysteine ligase (GCLc) was…”
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  3. 3
    Effects of alteration in levels of subunits of γ-glutamatecysteine ligase in Drosophila melanogaster and Drosophila S2 cells

    Effects of alteration in levels of subunits of γ-glutamatecysteine ligase in Drosophila melanogaster and Drosophila S2 cells by Prabhudesai, Leena

    Published 01-01-2005
    “…Glutathione (GSH), a tripeptide, plays several important roles in the antioxidative system. A decrease in intracellular glutathione levels results in…”
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