Search Results - "Prabhu, Gurpur Rakesh D"
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Sample Flow Rate Scan in Electrospray Ionization Mass Spectrometry Reveals Alterations in Protein Charge State Distribution
Published in Analytical chemistry (Washington) (06-10-2020)“…Sample flow rate is one of the parameters that influence the sensitivity of electrospray ionization (ESI) mass spectrometry. By varying the sample flow rate,…”
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Moderate Signal Enhancement in Electrospray Ionization Mass Spectrometry by Focusing Electrospray Plume with a Dielectric Layer around the Mass Spectrometer's Orifice
Published in Molecules (Basel, Switzerland) (01-01-2024)“…Electrospray ionization (ESI) is among the commonly used atmospheric pressure ionization techniques in mass spectrometry (MS). One of the drawbacks of ESI is…”
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Automation of mass spectrometric detection of analytes and related workflows: A review
Published in Talanta (Oxford) (01-02-2020)“…The developments in mass spectrometry (MS) in the past few decades reveal the power and versatility of this technology. MS methods are utilized in routine…”
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Facilitating chemical and biochemical experiments with electronic microcontrollers and single-board computers
Published in Nature protocols (01-03-2020)“…Since the advent of modern science, researchers have had to rely on their technical skills or the support of specialized workshops to construct analytical…”
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Telechemistry 2.0: Remote monitoring of fluorescent chemical reactions
Published in HardwareX (01-10-2021)“…[Display omitted] Implementation of the Internet-of-Things in chemistry research has the potential to improve research methodologies. Here, we describe a…”
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Elevating Chemistry Research with a Modern Electronics Toolkit
Published in Chemical reviews (09-09-2020)“…With the rapid development of high technology, chemical science is not as it used to be a century ago. Many chemists acquire and utilize skills that are well…”
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The dawn of unmanned analytical laboratories
Published in TrAC, Trends in analytical chemistry (Regular ed.) (01-03-2017)“…The twentieth century has brought enormous developments in instrumentation for chemical analysis. However, most of the state-of-the-art analytical instruments…”
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Microanalysis Using Acoustically Actuated Droplets Pinned Onto a Thread
Published in IEEE access (2019)“…An acoustic wave-assisted microscale assay platform is demonstrated. Liquid droplets containing samples and reagents are dispensed and pinned onto a…”
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Tuning Electrospray Ionization with Low-Frequency Sound
Published in Journal of the American Society for Mass Spectrometry (05-10-2022)“…Electrospray ionization (ESI) mass spectrometry (MS) is one of the key techniques used in biomolecular analysis nowadays. It relies on formation of…”
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Correction for “Tuning Electrospray Ionization with Low-Frequency Sound”
Published in Journal of the American Society for Mass Spectrometry (01-03-2023)Get full text
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Are Most Micrometer Droplets (>10 μm) Wasted in Electrospray Ionization? An Insight from Real-Time High-Speed Imaging
Published in Analytical chemistry (Washington) (03-10-2023)“…Electrospray ionization (ESI) is one of the main techniques used in mass spectrometry (MS) of nonvolatile compounds. ESI is a disordered process, in which a…”
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High-Speed Schlieren Imaging of Vapor Formation in Electrospray Plume
Published in Journal of the American Society for Mass Spectrometry (07-02-2024)“…Previous mechanistic descriptions of electrosprays mostly focused on the dynamics of Taylor cones, initial droplets, and progeny droplets. However, vapor…”
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Scanning pH-metry for Observing Reversibility in Protein Folding
Published in Biochemistry (Easton) (01-11-2022)“…One of the main factors affecting protein structure in solution is pH. Traditionally, to study pH-dependent conformational changes in proteins, the…”
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Observation of Protein Unfolding during pH Ramp Evoked by Lipase-Catalyzed Ester Hydrolysis
Published in Journal of the American Society for Mass Spectrometry (04-10-2023)“…Studies of protein folding often involve offline experimental methods such as titrating protein samples with denaturants or equilibrating them in the presence…”
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Programmable flow rate scanner for evaluating detector sensitivity regime
Published in Sensors and actuators. B, Chemical (01-03-2019)“…[Display omitted] •An automated flow rate optimization system is demonstrated.•It comprises a peristaltic pump and a single-board computer.•The slope of…”
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Temporal Analysis of Conformers in the Course of pH Scan Directed by Urea–Urease ReactionA “Protein Clock”
Published in Analytical chemistry (Washington) (16-07-2019)“…We demonstrate an analytical approach to monitor the effect of pH on protein tertiary structure. An autocatalytic enzyme reaction is used to stimulate…”
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Portable fizzy extraction ion-mobility spectrometry system
Published in Analytica chimica acta (29-04-2022)“…Fizzy extraction (FE) is a technique that utilizes effervescence phenomenon to extract volatile organic compounds (VOCs) from liquid matrices for subsequent…”
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Catalytic Oxygenation-Mediated Extraction as a Facile and Green Way to Analyze Volatile Solutes
Published in Analytical chemistry (Washington) (29-06-2021)“…Sparging-based methods have long been used to liberate volatile organic compounds (VOCs) from liquid sample matrices prior to analysis. In these methods, a…”
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Flat Disc-Shaped Sampling Probe and Online Re-extraction Apparatus for Mass Spectrometric Analysis of Skin Metabolites: A Proof of Concept
Published in Journal of the American Society for Mass Spectrometry (01-12-2021)“…Sweat analysis provides an alternative and noninvasive way of clinical diagnostics. However, sampling and transferring sweat-derived samples to analytical…”
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