Search Results - "Prabhakar, Y S"
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Clinical and radiological findings in chlorfenapyr poisoning
Published in Annals of the Indian Academy of Neurology (01-04-2013)“…This is a case report of suicidal ingestion of chlorfenapyr, presenting with neurological complications after a latent period of more than a week, and rapidly…”
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Topological descriptors in modeling the HIV inhibitory activity of 2-aryl-3-pyridyl-thiazolidin-4-ones
Published in Combinatorial chemistry & high throughput screening (01-08-2005)“…The HIV-1 RT inhibitory activity of 2-(2,6-dihalophenyl)-3-(substituted pyridin-2-yl)-thiazolidin-4-ones has been analyzed with different topological…”
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Identification of Adjacent NNRTI Binding Pocket in Multi-mutated HIV1- RT Enzyme Model: An in silico Study
Published in Current HIV research (01-01-2018)“…A possible strategy to combat mutant strains is to have a thorough structural evaluation before and after mutations to identify the diversity in the…”
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QSAR of 2-(4-methylsulphonylphenyl)pyrimidine derivatives as cyclooxygenase-2 inhibitors: simple structural fragments as potential modulators of activity
Published in Journal of enzyme inhibition and medicinal chemistry (01-04-2012)“…The cyclooxygenase-2 (COX-2) inhibitory activity of 2-(4-methylsulphonylphenyl)pyrimidine derivatives has been quantitatively analyzed in terms of Dragon…”
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Topological descriptors in modeling malonyl coenzyme A decarboxylase inhibitory activity: N-Alkyl-N-(1,1,1,3,3,3-hexafluoro-2-hydroxypropylphenyl)amide derivatives
Published in Journal of enzyme inhibition and medicinal chemistry (01-02-2009)“…The malonyl-CoA decarboxylase (MCD) inhibition activity of derivatives of N-alkyl-N-(1,1,1,3,3,3-hexafluoro-2-hydroxypropylphenyl)amide has been analyzed…”
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CoMFA and CoMSIA analysis of tetrahydroquinolines as potential antimalarial agents
Published in SAR and QSAR in environmental research (01-07-2011)“…Comparative molecular field analysis (CoMFA) and comparative molecular similarity indices analysis (CoMSIA) were used on a dataset of compounds, some of them…”
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Combinatorial protocol in multiple linear regression/partial least-squares directed rationale for the caspase-3 inhibition activity of isoquinoline-1,3,4-trione derivatives
Published in SAR and QSAR in environmental research (01-01-2010)“…The caspase-3 inhibition activity of isoquinoline-1,3,4-trione derivatives has been analysed with the topological and molecular features from Dragon software…”
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A quantitative structure-activity relationship study on serotonin 5-HT6 receptor ligands: indolyl and piperidinyl sulphonamides
Published in SAR and QSAR in environmental research (01-04-2010)“…The serotonin 5-HT 6 binding affinity of indolyl- and piperidinyl-sulphonamide derivatives has been analysed with topological and molecular features with…”
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Modeling of the growth hormone secretagogue receptor antagonistic activity using chemometric tools
Published in Journal of enzyme inhibition and medicinal chemistry (01-08-2009)“…A quantitative structure-activity relationship (QSAR) study has been carried out on growth hormone secretagogue receptor antagonistic activity of the…”
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Modeling of vascular endothelial growth factor receptor 2 (VEGFR2) kinase inhibitory activity of 2-anilino-5-aryloxazoles using chemometric tools
Published in Journal of enzyme inhibition and medicinal chemistry (01-02-2009)“…The structure-activity models of the VEGFR2 kinase inhibitory activity of the derivatives of 2-anilino-5-aryloxazole have been investigated using Combinatorial…”
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A case report on trans-fibular approach to distal tibial giant cell tumor
Published in MRIMS journal of health sciences (2016)“…Surgical excision of tumors of distal tibia situated specially in poster lateral aspect may be difficult to visualize in its entirety by antero-lateral…”
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Modified French osteotomy of humerus for post traumatic cubitus varus
Published in MRIMS journal of health sciences (2016)“…Background: The cubitus varus is the most common long term complication of the supra-condylar fractures of the humerus in children .Though the deformity is…”
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QSAR study of HMGR inhibitors: 7-(heteroaryl)-3,5-dihydroxy-6-heptenoic (-heptanoic) acids
Published in Drug design and discovery (1992)“…The 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGR) inhibitory activity of pyridine- and pyrimidine-substituted 3,5-dihydroxyhept-6(E)-enoic acids and…”
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On the ethnomedical significance of the Arjun tree, Terminalia arjuna (Roxb.) Wight & Arnot
Published in Journal of ethnopharmacology (01-07-1987)“…Terminalia arjuna is an important cardiotonic plant described in the Ayurveda, the ancient Indian medical science. It is also believed to have the ability to…”
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Early results of treatment of idiopathic club-foot using Ponseti method
Published in MRIMS journal of health sciences (2015)“…Idiopathic club foot is one of the most common problems in pediatric orthopedics. It is characterized by a three dimensional deformity of the foot and the…”
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Synthesis and QSAR studies on thiazolidinones as anti-HIV agents
Published in Combinatorial chemistry & high throughput screening (01-08-2005)“…Selected 4-thiazolidinone have been synthesized and tested as anti-HIV activity. The results of the in vitro tests showed that one of the compounds, 5,…”
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Quantum QSAR of the antirhinoviral activity of 9-benzylpurines
Published in Drug design and delivery (1991)“…The antirhinoviral activity of previously described 9-benzylpurines was quantitatively analysed using Huckel molecular orbital generated electronic parameters…”
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QSAR study on the antiviral activity of 2,6,9-substituted purines and related analogues
Published in Indian journal of biochemistry & biophysics (01-10-1990)Get more information
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Hepatoprotective effects of Wedelia calendulacea
Published in Journal of ethnopharmacology (01-02-1989)“…The alcoholic extract of whole plant Wedelia calendulacea exhibited protective activity against carbon tetrachloride-induced liver injury in vivo. The extract…”
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