Search Results - "Prabakaran, Indira"

CDH2/N-cadherin and early diagnosis of invasion in patients with ductal carcinoma in situ by Guvakova, Marina A., Prabakaran, Indira, Wu, Zhengdong, Hoffman, Daniel I., Huang, Ye, Tchou, Julia, Zhang, Paul J.

“…Purpose This proof-of-concept study investigates gene expression in core needle biopsies (CNB) to predict whether individuals diagnosed with ductal carcinoma…”
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Rap2A Is Upregulated in Invasive Cells Dissected from Follicular Thyroid Cancer by Grau, Jillian R., Lewis, Robert, Fraker, Douglas L., Guvakova, Marina A., Prabakaran, Indira

“…The development of molecular biomarkers (BMs) of follicular thyroid carcinoma is aimed at advancing diagnosis of follicular neoplasm, as histological…”
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Abstract B24: The diagnostic power of direct mRNA profiling in breast cancer core biopsy by Prabakaran, Indira, Zhang, Paul J., Guvakova, Marina

“…Abstract Background: Worldwide, biopsy is the gold standard for pathological assessment of cancer. Routinely, immunohistochemistry (IHC) can be performed to…”
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Gaussian Mixture Models for Probabilistic Classification of Breast Cancer by Prabakaran, Indira, Wu, Zhengdong, Lee, Changgun, Tong, Brian, Steeman, Samantha, Koo, Gabriel, Zhang, Paul J, Guvakova, Marina A

“…In the era of omics-driven research, it remains a common dilemma to stratify individual patients based on the molecular characteristics of their tumors. To…”
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Abstract 5283: Vav2 oncoprotein up regulation may predict the aggressive subtype of ductal carcinoma in situ by Guvakova, Marina A., Jiang, Yun Qing, Prabakaran, Indira, Wan, Fei, Mitra, Nandita, Zhang, Paul J., Fraker, Douglas L.

“…Abstract Background: A subset of patients with ductal carcinoma in situ (DCIS) will develop invasive breast cancer (IBC). To date, there are no effective…”
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The small GTPase Rap1 promotes cell movement rather than stabilizes adhesion in epithelial cells responding to insulin-like growth factor I by Guvakova, Marina A, Lee, William S Y, Furstenau, Dana K, Prabakaran, Indira, Li, David C, Hung, Rupert, Kushnir, Natasha

“…The Ras-related GTPase Rap1 promotes cell adhesion and migration. Although the significance of Rap1 contribution to cell migration is increasingly being…”
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Abstract B40: The quest for biomarkers of progressive DCIS using archived tissue by Guvakova, Marina A., Jiang, YunQing, Prabakaran, Indira, Wan, Fei, Mitra, Nandita, Fraker, Douglas L., Zhang, Paul J.

“…Abstract Background: Presently, an indolent ductal carcinoma in situ (DCIS) cannot be distinguished from a progressive tumor, making the appropriate treatment…”
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Abstract C23: The quest for biomarkers of progressive DCIS using archived tissue by Guvakova, Marina A., Jiang, YunQing, Prabakaran, Indira, Wan, Fei, Mitra, Nandita, Fraker, Douglas L., Zhang, Paul J.

“…Abstract Background: Presently, an indolent ductal carcinoma in situ (DCIS) cannot be distinguished from a progressive tumor, making the appropriate treatment…”
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An integrated approach to measuring tumor oxygen status using human melanoma xenografts as a model by MENON, Chandrakala, POLIN, Glenn M, FRAKER, Douglas L, PRABAKARAN, Indira, HSI, Alex, CHEUNG, Cecil, CULVER, Joseph P, PINGPANK, James F, SEHGAL, Chandra S, YODH, Arjun G, BUERK, Donald G

“…Tumor oxygen status is a reliable prognostic marker that impacts malignant progression and outcome of tumor therapy. However, tumor oxygenation is…”
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Vav2 protein overexpression marks and may predict the aggressive subtype of ductal carcinoma in situ by Jiang, YunQing, Prabakaran, Indira, Wan, Fei, Mitra, Nandita, Furstenau, Dana K, Hung, Rupert K, Cao, Siyuan, Zhang, Paul J, Fraker, Douglas L, Guvakova, Marina A

“…A subset of patients with ductal carcinoma in situ (DCIS) will develop invasive breast cancer (IBC). To date, there are no effective predictive biomarkers for…”
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Tumoricidal activity of high‐dose tumor necrosis factor‐α is mediated by macrophage‐derived nitric oxide burst and permanent blood flow shutdown by Menon, Chandrakala, Bauer, Todd W., Kelley, Scott T., Raz, Dan J., Bleier, Joshua I., Patel, Krina, Steele, Kirsten, Prabakaran, Indira, Shifrin, Alexander, Buerk, Donald G., Sehgal, Chandra M., Fraker, Douglas L.

“…This study investigates the role of tumor nitric oxide (NO) and vascular regulation in tumor ulceration following high‐dose tumor necrosis factor‐α (TNF)…”
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Virus-Mediated Oncolysis of Thyroid Cancer by a Replication-Selective Adenovirus Driven by a Thyroglobulin Promoter-Enhancer Region by Kesmodel, Susan, Prabakaran, Indira, Canter, Robert, Menon, Chandrakala, Molnar-Kimber, Kathy, Fraker, Douglas

“…Context: Currently, there is no effective treatment for iodine-resistant thyroid cancers. Objective: As a new approach to treatment, the efficacy of…”
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TNF-alpha downregulates vascular endothelial Flk-1 expression in human melanoma xenograft model by Menon, Chandrakala, Iyer, Malini, Prabakaran, Indira, Canter, Robert J, Lehr, Shannon C, Fraker, Douglas L

“…High-dose TNF with melphalan has significant antitumor activity in regional perfusion of the limbs and liver in human malignancies. TNF is believed to target…”
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Interferon-β gene therapy improves survival in an immunocompetent mouse model of carcinomatosis by Hendren, Samantha K, Prabakaran, Indira, Buerk, Donald G, Karakousis, Giorgos, Feldman, Michael, Spitz, Francis, Menon, Chandrakala, Fraker, Douglas L

“…Interferon-β (IFNβ) has multiple antitumor effects; however, its use has been limited by its short half-life in vivo. This limitation may be overcome by IFNβ…”
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Mature CD83 super(+) dendritic cells infected with recombinant gp 100 vaccinia virus stimulate potent antimelanoma T cells by Prabakaran, Indira, Menon, Chandrakala, Xu, Shuwen, Gomez-Yafal, Alicia, Czerniecki, Brian J, Fraker, Douglas L

“…Background: Mature dendritics cells (DCs) are potent antigen-presenting cells that activate naive T lymphocytes and initiate cellular immune responses. The…”
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Mature CD83(+) dendritic cells infected with recombinant gp100 vaccinia virus stimulate potent antimelanoma T cells by Prabakaran, Indira, Menon, Chandrakala, Xu, Shuwen, Gómez-Yafal, Alicia, Czerniecki, Brian J, Fraker, Douglas L

“…Mature dendritic cells (DCs) are potent antigen-presenting cells that activate naive T lymphocytes and initiate cellular immune responses. The ability of…”
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Mature CD83+ dendritic cells infected with recombinant gp 100 vaccinia virus stimulate potent antimelanoma T cells by Prabakaran, Indira, Menon, Chandrakala, Xu, Shuwen, Gómez-Yafal, Alicia, Czerniecki, Brian J., Fraker, Douglas L.

“…Mature dendritics cells (DCs) are potent antigen-presenting cells that activate naive T lymphocytes and initiate cellular immune responses. The ability of…”
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Eppendorf pO2 histograph and recessed pO2 microelectrode as methods of measuring in vivo oxygen tension in a murine tumor model by Polin, Glenn M, Bauer, Todd W, Buerk, Donald, Hsi, Alex, Prabakaran, Indira, Menon, Chandrakala, Fraker, Douglas L

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Eppendorf pO 2 histograph and recessed pO 2 microelectrode as methods of measuring in vivo oxygen tension in a murine tumor model by Polin, Glenn M, Bauer, Todd W, Buerk, Donald, Hsi, Alex, Prabakaran, Indira, Menon, Chandrakala, Fraker, Douglas L

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Expression of the La Crosse M segment proteins in a recombinant vaccinia expression system mediates pH-dependent cellular fusion by Jacoby, D R, Cooke, C, Prabakaran, I, Boland, J, Nathanson, N, Gonzalez-Scarano, F

“…To study the expression of La Crosse virus (LAC) glycoproteins, G1 and G2, we constructed a cDNA copy of the open reading frame (ORF) of the middle RNA segment…”
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