Search Results - "Préat, Veronique"
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Emerging delivery platforms for mucosal administration of biopharmaceuticals: a critical update on nasal, pulmonary and oral routes
Published in Expert opinion on drug delivery (02-01-2017)“…Protein and peptide-based drugs are preferred therapeutics due to their specificity but are mainly administered by injection. Alternative routes for peptide…”
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Evaluation of lauroyl-gemcitabine-loaded hydrogel efficacy in glioblastoma rat models
Published in Nanomedicine (London, England) (01-08-2018)“…Anticancer drug-loaded hydrogels are a promising strategy for the local treatment of incurable brain tumors such as glioblastoma (GBM). Recently, we…”
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3
Antimicrobial peptide-gold nanoscale therapeutic formulation with high skin regenerative potential
Published in Journal of controlled release (28-09-2017)“…Chronic skin wounds affect ≈3% of persons aged >60years (Davies et al., 2007) [1]. These wounds are typically difficult to heal by conventional therapies and…”
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In vitro and in vivo efficacy of edelfosine-loaded lipid nanoparticles against glioma
Published in Journal of controlled release (20-12-2011)“…Edelfosine is the prototype molecule of a family of anticancer drugs collectively known as synthetic alkyl-lysophospholipids. This drug holds promise as a…”
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To exploit the tumor microenvironment: Passive and active tumor targeting of nanocarriers for anti-cancer drug delivery
Published in Journal of controlled release (01-12-2010)“…Because of the particular characteristics of the tumor microenvironment and tumor angiogenesis, it is possible to design drug delivery systems that…”
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6
Immunotherapy for glioblastoma: the promise of combination strategies
Published in Journal of experimental & clinical cancer research (25-01-2022)“…Glioblastoma (GBM) treatment has remained almost unchanged for more than 20 years. The current standard of care involves surgical resection (if possible)…”
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Overcoming the intestinal barrier: A look into targeting approaches for improved oral drug delivery systems
Published in Journal of controlled release (10-06-2020)“…Oral drug administration is one of the most preferred and simplest routes among both patients and formulation scientists. Nevertheless, orally delivery of some…”
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Drug delivery challenges and future of chemotherapeutic nanomedicine for glioblastoma treatment
Published in Journal of controlled release (10-07-2018)“…Glioblastoma (GBM) is one of the most aggressive and deadliest central nervous system tumors, and the current standard treatment is surgery followed by…”
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RGD-Based Strategies To Target Alpha(v) Beta(3) Integrin in Cancer Therapy and Diagnosis
Published in Molecular pharmaceutics (05-11-2012)“…The integrin αvβ3 plays an important role in angiogenesis. It is expressed on tumoral endothelial cells as well as on some tumor cells. RGD peptides are…”
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An overview of in vitro, ex vivo and in vivo models for studying the transport of drugs across intestinal barriers
Published in Advanced drug delivery reviews (01-08-2021)“…[Display omitted] •Oral absorption depends on drug, formulation and gastrointestinal tract.•Different preclinical models are used to evaluate the intestinal…”
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Cancer DNA vaccines: current preclinical and clinical developments and future perspectives
Published in Journal of experimental & clinical cancer research (05-04-2019)“…The recent developments in immuno-oncology have opened an unprecedented avenue for the emergence of vaccine strategies. Therapeutic DNA cancer vaccines are now…”
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A nanoemulsion/micelles mixed nanosystem for the oral administration of hydrophobically modified insulin
Published in Drug delivery and translational research (01-04-2021)“…The potential of nanoemulsions for the oral administration of peptides is still in its early stage. The aim of the present work was to rationally design,…”
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Surface Modification of Lipid-Based Nanoparticles
Published in ACS nano (24-05-2022)“…There is a growing interest in the development of lipid-based nanocarriers for multiple purposes, including the recent increase of these nanocarriers as…”
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Rationally designed drug delivery systems for the local treatment of resected glioblastoma
Published in Advanced drug delivery reviews (01-10-2021)“…[Display omitted] Glioblastoma (GBM) is a particularly aggressive brain cancer associated with high recurrence and poor prognosis. The standard of care,…”
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Vitamin E-based nanomedicines for anti-cancer drug delivery
Published in Journal of controlled release (28-05-2014)“…This review aims to highlight the development of novel vitamin E conjugates for the vectorization of active pharmaceutical ingredients through…”
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Mechanisms of transport of polymeric and lipidic nanoparticles across the intestinal barrier
Published in Advanced drug delivery reviews (15-11-2016)“…Unraveling the mechanisms of nanoparticle transport across the intestinal barrier is essential for designing more efficient nanoparticles for oral…”
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PLGA-based nanoparticles: An overview of biomedical applications
Published in Journal of controlled release (20-07-2012)“…Poly(lactic-co-glycolic acid) (PLGA) is one of the most successfully developed biodegradable polymers. Among the different polymers developed to formulate…”
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Fate of polymeric nanocarriers for oral drug delivery
Published in Current opinion in colloid & interface science (01-06-2011)“…This review will focus on two polymeric nanocarriers: nanoparticles and micelles that have been studied for oral drug delivery at preclinical level. Their…”
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Nanocarrier-based drug combination therapy for glioblastoma
Published in Theranostics (2020)“…The current achievements in treating glioblastoma (GBM) patients are not sufficient because many challenges exist, such as tumor heterogeneity, the blood brain…”
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Iron oxide-loaded nanotheranostics: Major obstacles to in vivo studies and clinical translation
Published in Journal of controlled release (28-01-2015)“…A major issue in current cancer therapies is the lack of selectivity, which leads to damage in healthy tissues. Therefore, researchers have focused on numerous…”
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