Search Results - "Pozzetti, Laura"
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In Vitro Evaluation of Mucoadhesive Films for Gingival Administration of Lidocaine
Published in AAPS PharmSciTech (01-12-2013)“…The aim of this study was the optimization of a lidocaine-based film formulation for the prevention of pain from needle prick during the injection of local…”
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2
Glucoraphasatin and Glucoraphenin, a Redox Pair of Glucosinolates of Brassicaceae, Differently Affect Metabolizing Enzymes in Rats
Published in Journal of agricultural and food chemistry (11-07-2007)“…Brassica vegetables are an important dietary source of glucosinolates (GLs), whose breakdown products exhibit anticancer activity. The protective properties of…”
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Effect of licorice and glycyrrhizin on murine liver CYP-dependent monooxygenases
Published in Life sciences (1973) (1998)“…This study is aimed to investigate the effect of the prolonged intake of conspicuous amounts of licorice (LE), or its natural constituent glycyrrhizin (G) on…”
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Ursodeoxycholic acid (UDCA) prevents DCA effects on male mouse liver via up-regulation of CXP and preservation of BSEP activities
Published in Hepatology (Baltimore, Md.) (01-08-2002)“…To investigate whether ursodeoxycholic acid (UDCA) can prevent metabolic impairment induced by deoxycholic acid (DCA), we evaluated the effects of these bile…”
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5
Induction of CYP2B1 mediated pentoxyresorufin O-dealkylase activity in different species, sex and tissue by prototype 2B1-inducers
Published in Chemico-biological interactions (30-03-1995)“…The induction of CYP2B1 mediated pentoxyresorufm O-dealkylase (PROD) activity by various xenobiotics was explored in liver, kidney and lung from a variety of…”
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Glucoraphanin, the bioprecursor of the widely extolled chemopreventive agent sulforaphane found in broccoli, induces phase-I xenobiotic metabolizing enzymes and increases free radical generation in rat liver
Published in Mutation research (20-03-2006)“…Epidemiological and animal studies linking high fruit and vegetable consumption to lower cancer risk have strengthened the belief that long-term administration…”
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7
High-dose vitamin A
Published in The Lancet (British edition) (01-09-2007)Get full text
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Induction and suppression of cytochrome P450 isoenzymes and generation of oxygen radicals by procymidone in liver, kidney and lung of CD1 mice
Published in Mutation research (19-06-2003)“…Although chronic administration of procymidone (a widely used dicarboximide fungicide) leads to an increased incidence of liver tumors in mice, short-term…”
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Testosterone hydroxylase in evaluating induction and suppression of murine CYP isoenzymes by fenarimol
Published in Archives of toxicology (18-04-1996)Get full text
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Induction of cytochrome P450 enzymes and over-generation of oxygen radicals in beta-carotene supplemented rats
Published in Carcinogenesis (New York) (01-09-2001)“…Effects of beta-carotene (βCT) on microsomal CYP-linked monooxygenases were investigated using both the regio- and stereo-selective hydroxylation of…”
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Perturbation of cytochrome P450, generation of oxidative stress and induction of DNA damage in Cyprinus carpio exposed in situ to potable surface water
Published in Mutation research (10-01-2007)“…Epidemiological evidence suggests a link between consumption of chlorinated drinking water and various cancers. Chlorination of water rich in organic chemicals…”
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12
The nature of prooxidant activity of vitamin C
Published in Life sciences (1973) (1999)“…It was recently reported that vitamin C (500 mg/day for 6 weeks) administered as a dietary supplement to healthy humans exhibits a prooxidant, as well as an…”
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13
Cruciferous vegetables and lung cancer
Published in Mutation research (01-05-2007)Get full text
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Biomarkers of effect in evaluating metalaxyl cocarcinogenesis selective induction of murine CYP 3A isoform
Published in Mutation Research/Environmental Mutagenesis and Related Subjects (12-12-1996)“…The ability of metalaxyl, whose mutagenic/cocarcinogenic activity has as yet not been clarified, to affect specific biomarkers related to non-genotoxic…”
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15
Bile acid structure and selective modulation of murine hepatic cytochrome P450–linked enzymes
Published in Hepatology (Baltimore, Md.) (01-09-1999)“…We examined the effects of the administration of different bile acids on in vivo hepatic murine cytochrome P450 (CYP) content, nicotinamide adenine…”
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16
Ursodeoxycholic acid (UDCA) prevents DCA effects on male mouse liver via up-regulation of CYP [correction of CXP] and preservation of BSEP activities
Published in Hepatology (Baltimore, Md.) (01-08-2002)“…To investigate whether ursodeoxycholic acid (UDCA) can prevent metabolic impairment induced by deoxycholic acid (DCA), we evaluated the effects of these bile…”
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Induction and suppression of murine CYP-mediated biotransformation by dithianon: organ- and sex-related differences
Published in Cancer letters (01-07-1999)“…With the aim of evaluating the co-carcinogenic properties of dithianon, the regio- and stereo-selective hydroxylation of testosterone was used as a…”
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Molecular non-genetic biomarkers related to Fenarimol cocarcinogenesis: organ- and sex-specific CYP induction in rat
Published in Cancer letters (29-03-1996)“…Selective biochemical markers of effect have been used to evaluate some non-genotoxic cocarcinogenic properties of Fenarimol. Several CYP-dependent reactions…”
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20
Development of basal and induced testosterone hydroxylase activity in the chicken embryo in ovo
Published in British journal of pharmacology (01-09-1997)“…1 The sensitivity of the developing embryo to xenobiotics is highly dependent on the expression of metabolizing enzymes including cytochromes P450 (CYP). In…”
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