Search Results - "Pozhydaieva, Nadiia"
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Integrated Omics Reveal Time-Resolved Insights into T4 Phage Infection of E. coli on Proteome and Transcriptome Levels
Published in Viruses (12-11-2022)“…Bacteriophages are highly abundant viruses of bacteria. The major role of phages in shaping bacterial communities and their emerging medical potential as…”
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2
Identification of NAD-RNA species and ADPR-RNA decapping in Archaea
Published in Nature communications (21-11-2023)“…NAD is a coenzyme central to metabolism that also serves as a 5′-terminal cap for bacterial and eukaryotic transcripts. Thermal degradation of NAD can generate…”
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3
Isolation and molecular characterization of the Salmonella Typhimurium orphan phage Arash
Published in BMC microbiology (19-10-2023)“…The current threat of multidrug resistant strains necessitates development of alternatives to antibiotics such as bacteriophages. This study describes the…”
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4
Y-Complex Proteins Show RNA-Dependent Binding Events at the Cell Membrane and Distinct Single-Molecule Dynamics
Published in Cells (Basel, Switzerland) (09-03-2022)“…Bacteria are dependent on rapid alterations in gene expression. A prerequisite for rapid adaptations is efficient RNA turnover, with endonuclease RNase Y…”
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5
Isolation and characterization of Septuagintavirus ; a novel clade of Escherichia coli phages within the subfamily Vequintavirinae
Published in Microbiology spectrum (03-09-2024)“…is a commensal inhabitant of the mammalian gut microbiota, frequently associated with various gastrointestinal diseases. There is increasing interest in…”
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6
Utilizing Golden Gate Assembly to Streamline CRISPR-Cas/NgTET-Based Phage Mutagenesis
Published in Methods in molecular biology (Clifton, N.J.) (2025)“…Phage engineering is an emerging technology due to the promising potential application of phages in medical and biotechnological settings. Targeted phage…”
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7
The enigmatic epitranscriptome of bacteriophages: putative RNA modifications in viral infections
Published in Current opinion in microbiology (01-02-2024)“…RNA modifications play essential roles in modulating RNA function, stability, and fate across all kingdoms of life. The entirety of the RNA modifications…”
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8
Molekulare Schnappschüsse der Phageninfektion
Published in Biospektrum (01-05-2023)“…Today, the clinical potential of antibiotics is almost exhausted, which has led to a renaissance of phage research and phage therapy. To maximize phage therapy…”
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9
A viral ADP-ribosyltransferase attaches RNA chains to host proteins
Published in Nature (London) (31-08-2023)“…The mechanisms by which viruses hijack the genetic machinery of the cells they infect are of current interest. When bacteriophage T4 infects Escherichia coli…”
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10
Application of the C3-Methyltransferase StspM1 for the Synthesis of the Natural Pyrroloindole Motif
Published in ACS catalysis (05-01-2024)“…Even though pyrroloindoles are widely present in natural products with different kinds of biological activities, their selective synthesis remains challenging…”
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11
Temporal epigenome modulation enables efficient bacteriophage engineering and functional analysis of phage DNA modifications
Published in PLoS genetics (04-09-2024)“…Lytic bacteriophages hold substantial promise in medical and biotechnological applications. Therefore a comprehensive understanding of phage infection…”
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12
Enzymatic C3-Methylation of Indoles Using Methyltransferase PsmDCrystal Structure, Catalytic Mechanism, and Preparative Applications
Published in ACS catalysis (18-11-2022)“…Enantioselective methylation is a challenging task in organic chemistry, yet often desirable in drug discovery and optimization. S-Adenosyl methionine…”
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13
Integrated Omics Reveal Time-Resolved Insights into T4 Phage Infection of IE. coli/I on Proteome and Transcriptome Levels
Published in Viruses (01-11-2022)“…Bacteriophages are highly abundant viruses of bacteria. The major role of phages in shaping bacterial communities and their emerging medical potential as…”
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14
Engineering Biocatalysts for the C−H Activation of Fatty Acids by Ancestral Sequence Reconstruction
Published in Angewandte Chemie International Edition (24-04-2024)“…Selective, one‐step C−H activation of fatty acids from biomass is an attractive concept in sustainable chemistry. Biocatalysis has shown promise for generating…”
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15
Shaping the Bacterial Epitranscriptome—5′‐Terminal and Internal RNA Modifications
Published in Advanced biology (01-08-2021)“…All domains of life utilize a diverse set of modified ribonucleotides that can impact the sequence, structure, function, stability, and the fate of RNAs, as…”
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16
Molekulare Schnappschüsse der Phageninfektion
Published in Biospektrum (01-05-2023)“…Today, the clinical potential of antibiotics is almost exhausted, which has led to a renaissance of phage research and phage therapy. To maximize phage therapy…”
Get full text
Journal Article -
17
Engineering Biocatalysts for the C−H Activation of Fatty Acids by Ancestral Sequence Reconstruction
Published in Angewandte Chemie (24-04-2024)“…Selective, one‐step C−H activation of fatty acids from biomass is an attractive concept in sustainable chemistry. Biocatalysis has shown promise for generating…”
Get full text
Journal Article