Search Results - "Powers, Matthew R"

Segmented Tube Reactors (STR): A Simple Tool To Screen Multiple Reactions in Parallel in Batch Mode within a Single Tube by Weiberth, Franz J, Powers, Matthew R, Gallin, Connor, McDonald, David

“…A simple tool to perform multiple reactions in parallel in batch mode in static segments within a single tube is described. The Segmented Tube Reactor (STR)…”
Get full text

Scale-Up of an Enantioselective Overman Rearrangement for an Asymmetric Synthesis of a Glycine Transporter 1 Inhibitor by Chandramouli, Sithamalli V, Ayers, Timothy A, Wu, Xiao-Dong, Tran, Loc T, Peers, James H, Disanto, Rocco, Roberts, Frederick, Kumar, Narendra, Jiang, Ying, Choy, Nakyen, Pemberton, Clive, Powers, Matthew R, Gardetto, Anthony J, D’Netto, Geoffrey A, Chen, Xuemin, Gamboa, Juan, Ngo, Duc, Copeland, Warren, Rudisill, Duane E, Bridge, Andrew W, Vanasse, Benoit J, Lythgoe, David J

“…An enantioselective Overman 3,3-sigmatropic rearrangement on a quinuclidine skeleton was developed for the pilot-plant synthesis of a glycine transporter 1…”
Get full text

Process Development of Selectively Benzoylated and Fluorinated Glycosyl Donors by Weiberth, Franz J, Gill, Harpal S, Jiang, Ying, Lee, George E, Lienard, Philippe, Pemberton, Clive, Powers, Matthew R, Subotkowski, Witold, Tomasik, Witold, Vanasse, Benoit J, Yu, Yong

“…Route selection, process development and large-scale preparation of selectively benzoylated and fluorinated d-glucopyranoses, required as glycosyl donors for…”
Get full text

Chemical Development of the Casein Kinase I - Epsilon Inhibitor: 3-(3-Fluorophenyl)sulfanyl-1H-pyrrolo[3,2-b]pyridine-2-carboxylic Acid Amide by Huang, Bao-Guo, Kubiak, Gregory, Shay, John J, Pemberton, Clive, Peers, James, Hanna, Reda G, Powers, Matthew R, Gamboa, Juan A, Gelormini, Ann M, Yarabe, Hyacinthe, Rudisill, Duane E

“…The development of a scalable process for 3-arylsulfanyl-1H-pyrrolo[3,2-b]pyridine-2-carboxylic acid amides (1), potent casein kinase I inhibitors, is…”
Get full text

Efficient Synthesis of AMP579, a Novel Adenosine A1/A2 Receptor Agonist by Sledeski, Adam W, Kubiak, Gregory G, O'Brien, Michael K, Powers, Matthew R, Powner, Tory H, Truesdale, Larry K

Get full text

Chemical Development of the Casein Kinase I - Epsilon Inhibitor: 3-(3-Fluorophenyl)sulfanyl-1 H -pyrrolo[3,2- b ]pyridine-2-carboxylic Acid Amide by Huang, Bao-Guo, Kubiak, Gregory, Shay, John J., Pemberton, Clive, Peers, James, Hanna, Reda G., Powers, Matthew R., Gamboa, Juan A., Gelormini, Ann M., Yarabe, Hyacinthe, Rudisill, Duane E.

Get full text