Search Results - "Powers, H J"

Trends in Antimicrobial Drug Development: Implications for the Future by Spellberg, Brad, Powers, John H., Brass, Eric P., Miller, Loren G., Edwards, John E.

“…The need for new antimicrobial agents is greater than ever because of the emergence of multidrug resistance in common pathogens, the rapid emergence of new…”
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Fluoroquinolone-Resistant Campylobacter Species and the Withdrawal of Fluoroquinolones from Use in Poultry: A Public Health Success Story by Nelson, Jennifer M., Chiller, Tom M., Powers, John H., Angulo, Frederick J.

“…Campylobacter species cause 1.4 million infections each year in the United States. Fluoroquinolones (e.g., ciprofloxacin) are commonly used in adults with…”
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Antimicrobial drug development – the past, the present, and the future by Powers, J.H.

“…Antimicrobial resistance has been an issue since the introduction into clinical use of the first agents in the 1940s. Although the discovery and development of…”
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Effects of an exercise and hypocaloric healthy eating program on biomarkers associated with long-term prognosis after early-stage breast cancer: a randomized controlled trial by Scott, E., Daley, A. J., Doll, H., Woodroofe, N., Coleman, R. E., Mutrie, N., Crank, H., Powers, H. J., Saxton, J. M.

“…Excess body weight at diagnosis and weight gain after breast cancer are associated with poorer long-term prognosis. This study investigated the effects of a…”
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Antioxidant supplementation enhances antioxidant capacity and mitigates oxidative damage following acute ischaemic stroke by ULLEGADDI, R, POWERS, H. J, GARIBALLA, S. E

“…To test whether supplementary antioxidants immediately following acute ischaemic stroke will enhance antioxidant capacity and mitigate oxidative damage. A…”
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Sensitivity of markers of DNA stability and DNA repair activity to folate supplementation in healthy volunteers by BASTEN, G. P, DUTHIE, S. J, PIRIE, L, VAUGHAN, N, HILL, M. H, POWERS, H. J

“…We have previously reported that supplementation with folic acid (1.2 mg day(-1) for 12 week) elicited a significant improvement in the folate status of 61…”
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Riboflavin and friends: Remarkably versatile vitamins by Powers, H. J.

“…Having been awarded the 2019 British Nutrition Foundation Annual Prize I had looked forward to delivering a lecture to assembled guests at the BNF Annual Day…”
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A double-blind randomized placebo cross-over controlled trial using the antioxidant vitamin E to treat reactive oxygen species associated male infertility by Kessopoulou, E, Powers, H J, Sharma, K K, Pearson, M J, Russell, J M, Cooke, I D, Barratt, C L

“…To determine the effectiveness of the in vivo administration of vitamin E as treatment for reactive oxygen species-associated male infertility…”
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Homocysteine-Induced Inhibition of Endothelium-Dependent Relaxation in Rabbit Aorta: Role for Superoxide Anions by Lang, Derek, Kredan, Mahmud B, Moat, Stuart J, Hussain, Syed A, Powell, Catherine A, Bellamy, Michael F, Powers, Hilary J, Lewis, Malcolm J

“…ABSTRACTHyperhomocysteinemia is associated with endothelial dysfunction, although its mechanism is unknown. Isometric tension recordings and lucigenin…”
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Research goals for folate and related B vitamin in Europe by Finglas, P.M, Meer, K. de, Molloy, A, Verhoef, P, Pietrzik, K, Powers, H.J, Straeten, D. van der, Jägerstad, M, Varela-Moreiras, G, Vliet, T. van

“…In the past decade, the understanding of folate bioavailability, metabolism and related health issues has increased, but several problems remain, including the…”
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Downstream effects on human low density lipoprotein of homocysteine exported from endothelial cells in an in vitro system by Nakano, E., Taiwo, F.A., Nugent, D., Griffiths, H.R., Aldred, S., Paisi, M., Kwok, M., Bhatt, P., Hill, M.H.E., Moat, S., Powers, H.J.

“…A model system is presented using human umbilical vein endothelial cells (HUVECs) to investigate the role of homocysteine (Hcy) in atherosclerosis. HUVECs are…”
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Antioxidant activity, packed cell transfusions, and outcome in premature infants by Silvers, K M, Gibson, A T, Russell, J M, Powers, H J

“…AIM To evaluate the relative importance of biochemical markers of antioxidant status, gestational age, and parameters of neonatal care in the clinical outcome…”
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Editorial Commentary: Asking the Right Questions: Morbidity, Mortality, and Measuring What's Important in Unbiased Evaluations of Antimicrobials by Powers, John H.

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Absence of luminal riboflavin disturbs early postnatal development of the gastrointestinal tract by YATES, C. A, EVANS, G. S, PEARSON, T, POWERS, H. J

“…An increase in the size and cellularity of duodenal crypts and a decreased incidence of bifurcating crypts is observed in response to very short-term feeding…”
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Reduction in plasma total homocysteine through increasing folate intake in healthy individuals is not associated with changes in measures of antioxidant activity or oxidant damage by MOAT, S. J, HILL, M. H, MCDOWELL, I. F. W, PULLIN, C. H, ASHFIELD-WATT, P. A. L, CLARK, Z. E, WHITING, J. M, NEWCOMBE, R. G, LEWIS, M. J, POWERS, H. J

“…Various mechanisms have been proposed to explain the association between plasma total homocysteine (tHcy) and risk of cardiovascular disease, including…”
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The effects of maternal intake and gestational age on materno-fetal transport of vitamin C in the guinea-pig by Das, S., Powers, H. J.

“…The effects of maternal intake and gestational age on materno-fetal transport of vitamin C were investigated in female Dunkin-Hartley guinea-pigs. Twenty-four…”
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Vitamin C therapy ameliorates vascular endothelial dysfunction in treated patients with homocystinuria by Pullin, C. H., Bonham, J. R., McDowell, I. F. W., Lee, P. J., Powers, H. J., Wilson, J. F., Lewis, M. J., Moat, S. J.

“…Objectives: We sought to investigate the effects of short‐ and long‐term vitamin C therapy on endothelial dysfunction in patients with homocystinuria…”
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Appropriate antimicrobial prescribing: approaches that limit antibiotic resistance by Colgan, R, Powers, J H

“…Since the introduction of antimicrobial agents, there has been an association between antibiotic use and the development of antimicrobial resistance…”
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Recommended approaches for the laboratory measurement of homocysteine in the diagnosis and monitoring of patients with hyperhomocysteinaemia by Moat, S J, Bonham, J R, Tanner, M S, Allen, J C, Powers, H J

“…Several recent studies have indicated that an increased concentration of plasma homocysteine is an independent risk factor for the premature development of…”
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Design, Conduct, and Analysis of Clinical Trials in Disease due to Methicillin‐Resistant Staphylococcus aureus by Powers, J H, Fleming, T R

“…Given the changing epidemiology of disease due to Staphylococcus aureus (SA), including the emergence of drug‐resistant organisms such as methicillin‐resistant…”
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