Search Results - "Powell, Justin A.C."

Discovery and Characterization of Novel CNS-Penetrant GPR55 Agonists by Hewer, Richard C., Christie, Louisa A., Doyle, Kevin J., Xu, Xiao, Roberts, Maxine J., Dickson, Louise, Cheung, Toni, Cadwalladr, David H., Pickford, Philip, Teall, Martin, Powell, Justin A. C., Sheardown, Steven, Narayana, Lakshminarayana, Brice, Nicola L., Dawson, Lee A., Carlton, Mark, Bürli, Roland W.

“…From our NETSseq-derived human brain transcriptomics data, we identified GPR55 as a potential molecular target for the treatment of motor symptoms in patients…”
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Synthesis and SAR of novel GPR39 agonists and positive allosteric modulators by Burley, Russell, Hewer, Richard C., Teall, Martin, Dickson, Louise, Ossola, Bernardino, Russell, Sam, Bender, Clare, Cheung, Toni, Powell, Justin A.C., Xu, Xiao, Brice, Nicola L., Otter, Lucy, Arimont, Marta, Kidd, Sarah L., Vidal, David, Dale, James W., Mervin, Lewis, Sore, Hannah F., Mateu, Natalia, Lakshminarayana, Narayana, Dawson, Lee A., Carlton, Mark, Bürli, Roland W.

“…[Display omitted] We report a significant decrease in transcription of the G protein-coupled receptor GPR39 in striatal neurons of Parkinson’s disease patients…”
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Molecular characterisation of a Rhodococcus ohp operon by Powell, J A, Archer, J A

“…The ohp operon of Rhodococcus strain V49 consists of five genes, ohpR, ohpA, ohpB, ohpC and ohpD which encode putative regulator and transport proteins and…”
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