Search Results - "Powell, Daniel A"

Cytoplasmic LPS Activates Caspase-11: Implications in TLR4-Independent Endotoxic Shock by Hagar, Jon A., Powell, Daniel A., Aachoui, Youssef, Ernst, Robert K., Miao, Edward A.

“…Inflammatory caspases, such as caspase-1 and -11, mediate innate immune detection of pathogens. Caspase-11 induces pyroptosis, a form of programmed cell death,…”
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Pertussis toxin stimulates IL-17 production in response to Bordetella pertussis infection in mice by Andreasen, Charlotte, Powell, Daniel A, Carbonetti, Nicholas H

“…In a mouse model of respiratory tract infection by Bordetella pertussis, bacteria multiply in the airways over the first week and are then cleared over the…”
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LPS remodeling is an evolved survival strategy for bacteria by Li, Yanyan, Powell, Daniel A., Shaffer, Scott A., Rasko, David A., Pelletier, Mark R., Leszyk, John D., Scott, Alison J., Masoudi, Ali, Goodlett, David R., Wang, Xiaoyuan, Raetz, Christian R. H., Ernst, Robert K.

“…Maintenance of membrane function is essential and regulated at the genomic, transcriptional, and translational levels. Bacterial pathogens have a variety of…”
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Systemic administration of antiretrovirals prior to exposure prevents rectal and intravenous HIV-1 transmission in humanized BLT mice by Denton, Paul W, Krisko, John F, Powell, Daniel A, Mathias, Melissa, Kwak, Youn Tae, Martinez-Torres, Francisco, Zou, Wei, Payne, Deborah A, Estes, Jacob D, Garcia, J Victor

“…Successful antiretroviral pre-exposure prophylaxis (PrEP) for mucosal and intravenous HIV-1 transmission could reduce new infections among targeted high-risk…”
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Genetic and Other Determinants for the Severity of Coccidioidomycosis: A Clinician's Perspective by Galgiani, John N, Hsu, Amy P, Powell, Daniel A, Vyas, Jatin M, Holland, Steven M

“…The endemic fungal infection, coccidioidomycosis, occurs after inhalation of one or very few spp. spores. Infections produce diverse clinical manifestations,…”
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Adaptive Immunity to Francisella tularensis and Considerations for Vaccine Development by Roberts, Lydia M, Powell, Daniel A, Frelinger, Jeffrey A

“…is an intracellular bacterium that causes the disease tularemia. There are several subspecies of whose ability to cause disease varies in humans. The most…”
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One Percent Tenofovir Applied Topically to Humanized BLT Mice and Used According to the CAPRISA 004 Experimental Design Demonstrates Partial Protection from Vaginal HIV Infection, Validating the BLT Model for Evaluation of New Microbicide Candidates by DENTON, Paul W, OTHIENO, Florence, WELCH, Brett D, KAY, Michael S, PAYNE, Deborah A, GALLAY, Philippe, APPELLA, Ettore, ESTES, Jacob D, MIN LU, VICTOR GARCIA, J, MARTINEZ-TORRES, Francisco, WEI ZOU, KRISKO, John F, FLEMING, Elisa, ZEIN, Sima, POWELL, Daniel A, WAHL, Angela, YOUN TAE KWAK

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Antiretroviral pre-exposure prophylaxis prevents vaginal transmission of HIV-1 in humanized BLT mice by DENTON, P.W, ESTES, J.D, SUN, Z, OTHIENO, F.A, WEI, B.L, WEGE, A.K, POWELL, D.A, PAYNE, D, HAASE, A.T, GARCIA, J.V

“…Worldwide, vaginal transmission now accounts for more than half of newly acquired HIV-1 infections. Despite the urgency to develop and implement novel…”
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TNFα Blockade Inhibits Both Initial and Continued Control of Pulmonary Coccidioides by Powell, Daniel A, Shubitz, Lisa F, Butkiewicz, Christine D, Trinh, Hien T, Donovan, Fariba M, Frelinger, Jeffrey A, Galgiani, John N

“…Tumor necrosis factor alpha (TNFα) is a pluripotent cytokine that is important in many infections, though its role in infection remains poorly understood. The…”
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Vaccine Protection of Mice With Primary Immunodeficiencies Against Disseminated Coccidioidomycosis by Powell, Daniel A, Hsu, Amy P, Butkiewicz, Christine D, Trinh, Hien T, Frelinger, Jeffrey A, Holland, Steven M, Galgiani, John N, Shubitz, Lisa F

“…Disseminated coccidioidomycosis (DCM), often a severe and refractory disease leading to poor outcomes, is a risk for people with certain primary…”
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Discovery of a Unique Set of Dog-Seroreactive Coccidioides Proteins Using Nucleic Acid Programmable Protein Array by Koehler, Megan A, Song, Lusheng, Grill, Francisca J, Shubitz, Lisa F, Powell, Daniel A, Galgiani, John N, Orbach, Marc J, Robb, Edward J, Chung, Yunro, Williams, Stacy A, Murugan, Vel, Park, Jin-Gyoon, LaBaer, Joshua, Lake, Douglas F, Magee, D Mitchell

“…Valley Fever (VF), caused by fungi in the genus , is a prevalent disease in southwestern and western parts of the United States that affects both humans and…”
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Vaccines to Prevent Coccidioidomycosis: A Gene-Deletion Mutant of Coccidioides Posadasii as a Viable Candidate for Human Trials by Galgiani, John N, Shubitz, Lisa F, Orbach, Marc J, Mandel, M Alejandra, Powell, Daniel A, Klein, Bruce S, Robb, Edward J, Ohkura, Mana, Seka, Devin J, Tomasiak, Thomas M, Monath, Thomas P

“…Coccidioidomycosis is an endemic fungal infection that is reported in up to 20,000 persons per year and has an economic impact close to $1.5 billion. Natural…”
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Reactivation of Coccidioidomycosis in a Mouse Model of Asymptomatic Controlled Disease by Shubitz, Lisa F, Powell, Daniel A, Dial, Sharon M, Butkiewicz, Christine D, Trinh, Hien T, Hsu, Amy P, Buntzman, Adam, Frelinger, Jeffrey A, Galgiani, John N

“…The majority of human coccidioidomycosis infections are asymptomatic or self-limited but may have sequestered spherules in highly structured granulomas. Under…”
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Role of Francisella Lipid A Phosphate Modification in Virulence and Long-Term Protective Immune Responses by KANISTANON, Duangjit, POWELL, Daniel A, HAJJAR, Adeline M, PELLETIER, Mark R, COHEN, Ilana E, SING WAY, Sing, SKERRETT, Shawn J, XIAOYUAN WANG, RAETZ, Christian R. H, ERNST, Robert K

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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The prrF-encoded small regulatory RNAs are required for iron homeostasis and virulence of Pseudomonas aeruginosa by Reinhart, Alexandria A, Powell, Daniel A, Nguyen, Angela T, O'Neill, Maura, Djapgne, Louise, Wilks, Angela, Ernst, Robert K, Oglesby-Sherrouse, Amanda G

“…Pseudomonas aeruginosa is an opportunistic pathogen that requires iron to cause infection, but it also must regulate the uptake of iron to avoid iron toxicity…”
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Δcps1 vaccine protects dogs against experimentally induced coccidioidomycosis by Shubitz, Lisa F., Robb, Edward J., Powell, Daniel A., Bowen, Richard A., Bosco-Lauth, Angela, Hartwig, Airn, Porter, Stephanie M., Trinh, Hien, Moale, Hilary, Bielefeldt-Ohmann, Helle, Hoskinson, James, Orbach, Marc J., Frelinger, Jeffrey A., Galgiani, John N.

“…•There is need for a vaccine to prevent coccidioidomycosis in dogs and humans.•Δcps1, an avirulent, live vaccine, appeared safe and well-tolerated in…”
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A Chronic Murine Disease Model of Coccidioidomycosis Using Coccidioides posadasii, Strain 1038 by Shubitz, Lisa F, Powell, Daniel A, Butkiewicz, Christine D, Lewis, M Lourdes, Trinh, Hien T, Frelinger, Jeffrey A, Orbach, Marc J, Galgiani, John N

“…Abstract Murine infections with most Coccidioides spp. strains are lethal by 3 weeks, limiting the study of immune responses. Coccidioides posadasii, strain…”
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A Natural Mouse Model for Neisseria Colonization by Ma, Mancheong, Powell, Daniel A, Weyand, Nathan J, Rhodes, Katherine A, Rendón, María A, Frelinger, Jeffrey A, So, Magdalene

“…Commensals are important for the proper functioning of multicellular organisms. How a commensal establishes persistent colonization of its host is little…”
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Viable spores of Coccidioides posadasii Δcps1 are required for vaccination and provide long lasting immunity by Shubitz, Lisa F., Powell, Daniel A., Trinh, Hien T., Lewis, M. Lourdes, Orbach, Marc J., Frelinger, Jeffrey A., Galgiani, John N.

“…Coccidioidomycosis is a systemic fungal infection for which a vaccine has been sought for over fifty years. The avirulent Coccidioides posadasii strain, Δcps1,…”
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Efficacy of Resistance to Francisella Imparted by ITY/NRAMP/SLC11A1 Depends on Route of Infection by Powell, Daniel A, Frelinger, Jeffrey A

“…Natural resistance-associated macrophage protein (NRAMP) encoded by the gene is a membrane-associated transporter of divalent metal ions. Murine has two known…”
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