Search Results - "Powell, D. J."
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High-affinity FRβ-specific CAR T cells eradicate AML and normal myeloid lineage without HSC toxicity
Published in Leukemia (01-06-2016)“…Acute myeloid leukemia (AML) is an aggressive malignancy, and development of new treatments to prolong remissions is warranted. Chimeric antigen receptor (CAR)…”
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mTORC2 signalling regulates M2 macrophage differentiation in response to helminth infection and adaptive thermogenesis
Published in Nature communications (27-01-2017)“…Alternatively activated macrophages (M2) have an important function in innate immune responses to parasitic helminths, and emerging evidence also indicates…”
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A dose‐finding study of temsirolimus and liposomal doxorubicin for patients with recurrent and refractory bone and soft tissue sarcoma
Published in International journal of cancer (15-08-2013)“…There are few effective therapies for high‐risk sarcomas. Initial chemosensitivity is often followed by relapse. In vitro, mammalian target of rapamycin (mTOR)…”
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Expression of p53 and p53 47 are controlled by alternative mechanisms of messenger RNA translation initiation
Published in Oncogene (02-11-2006)“…P53 controls the growth and survival of cells by acting in response to a multitude of cellular stresses. It is, however, not yet fully understood how different…”
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Sirolimus and post transplant Cy synergistically maintain mixed chimerism in a mismatched murine model
Published in Bone marrow transplantation (Basingstoke) (01-10-2013)“…Because of the toxicity associated with myeloablative conditioning, nonmyeloablative regimens are increasingly being used in vulnerable patient populations…”
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Bacillus anthracis spores germinate extracellularly at air–liquid interface in an in vitro lung model under serum‐free conditions
Published in Journal of applied microbiology (01-09-2015)“…Aims To better understand the parameters that govern spore dissemination after lung exposure using in vitro cell systems. Methods and Results We evaluated the…”
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The RET/PTC3 oncogene : Metastatic solid-type papillary carcinomas in murine thyroids
Published in Cancer research (Chicago, Ill.) (01-12-1998)“…Our research goal is to better understand the mechanisms controlling the initiation and progression of thyroid diseases. One such disease, papillary thyroid…”
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Developments of NEWUOA for minimization without derivatives
Published in IMA journal of numerical analysis (01-10-2008)“…The NEWUOA software is described briefly, with some numerical results that show good efficiency and accuracy in the unconstrained minimization without…”
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Immunologic recovery following autologous stem-cell transplantation with pre- and posttransplantation rituximab for low-grade or mantle cell lymphoma
Published in Annals of oncology (01-06-2010)“…Rituximab may improve transplant outcomes but may delay immunologic recovery. Seventy-seven patients with low-grade or mantle cell lymphoma received autologous…”
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10
Using Advancements in Cable-Trapping to Overcome Barriers to Furbearer Management in the United States
Published in The Journal of wildlife management (01-07-2010)“…Harvest of furbearers through trapping has been challenged by anti-trapping organizations for centuries, with organizational goals often including prohibition…”
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Augmenting the Production Operators for Continuous Improvement
Published in 2022 IEEE International Conference on Industrial Engineering and Engineering Management (IEEM) (07-12-2022)“…This paper discusses how continuous improvement activities can be supported by augmenting the operators in production. After a brief literature background,…”
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Conference Proceeding -
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Salvage transplantation for allograft failure using fludarabine and alemtuzumab as conditioning regimen
Published in Bone marrow transplantation (Basingstoke) (01-03-2009)“…Graft failure after allogeneic blood or marrow transplantation, although generally uncommon, can be a devastating complication. This report includes the…”
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13
Perceptions of Risk and Adaptive Capacity Frame Decisions by Namibians Engaged in Ecotourism
Published in Great Plains research (2020)“…Ecotourism must address financial, ecological, and social expectations to be sustainable as a business venture. Therefore, decisions made by ecotourism…”
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Geography of Ecotourism Potential in the Great Plains: Incentives for Conservation
Published in Great Plains research (01-04-2018)“…Ecotourism on private lands may be an incentive for conservation because of potential profits to landowners. Conservation planners in southern Africa have…”
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Influence of chick hatch time and access to feed on broiler muscle development
Published in Poultry science (01-06-2016)“…The effect of hatch time and the timing of access to feed on growth rate and breast muscle development was assessed in Ross 308 broiler chickens. Chicks were…”
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ASP1 (BACE2) Cleaves the Amyloid Precursor Protein at the β-Secretase Site
Published in Molecular and cellular neuroscience (01-11-2000)“…Sequential proteolytic processing of the Amyloid Precursor Protein (APP) by β- and γ-secretases generates the 4-kDa amyloid (Aβ) peptide, a key component of…”
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The effect of nutritional status on myogenic gene expression of satellite cells derived from different muscle types
Published in Poultry science (01-09-2014)“…Satellite cells (SC) are a multipotential stem cell population responsible for facilitating posthatch muscle fiber hypertrophy. The proliferation and…”
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Expression and Localization of Hypoxia-Inducible Factor-1 Subunits in the Adult Rat Epididymis
Published in Biology of reproduction (01-04-2004)“…The epididymal epithelium contributes to formation of a luminal fluid that is essential for the protection of spermatozoa from a variety of insults including…”
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Influence of hatch time and access to feed on intramuscular adipose tissue deposition in broilers
Published in Poultry science (01-06-2016)“…The effect of hatch time and subsequent access to feed on intramuscular adipose tissue deposition was studied in the pectoralis major muscle of male Ross 308…”
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Adenosine receptors and cancer
Published in Handbook of experimental pharmacology (2009)“…The A(1), A(2A), A(2B) and A(3) G-protein-coupled cell surface adenosine receptors (ARs) are found to be upregulated in various tumor cells. Activation of the…”
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