Search Results - "Powell, D J"

High-affinity FRβ-specific CAR T cells eradicate AML and normal myeloid lineage without HSC toxicity by Lynn, R C, Feng, Y, Schutsky, K, Poussin, M, Kalota, A, Dimitrov, D S, Powell Jr, D J

“…Acute myeloid leukemia (AML) is an aggressive malignancy, and development of new treatments to prolong remissions is warranted. Chimeric antigen receptor (CAR)…”
Get full text

mTORC2 signalling regulates M2 macrophage differentiation in response to helminth infection and adaptive thermogenesis by Hallowell, R. W., Collins, S. L., Craig, J. M., Zhang, Y., Oh, M., Illei, P. B., Chan-Li, Y., Vigeland, C. L., Mitzner, W., Scott, A. L., Powell, J. D., Horton, M. R.

“…Alternatively activated macrophages (M2) have an important function in innate immune responses to parasitic helminths, and emerging evidence also indicates…”
Get full text

A dose‐finding study of temsirolimus and liposomal doxorubicin for patients with recurrent and refractory bone and soft tissue sarcoma by Thornton, K.A., Chen, A.R., Trucco, M.M., Shah, P., Wilky, B.A., Gul, N., Carrera‐Haro, M.A., Ferreira, M. Fogle, Shafique, U., Powell, J.D., Meyer, C.F., Loeb, D.M.

“…There are few effective therapies for high‐risk sarcomas. Initial chemosensitivity is often followed by relapse. In vitro, mammalian target of rapamycin (mTOR)…”
Get full text

Expression of p53 and p53 47 are controlled by alternative mechanisms of messenger RNA translation initiation by CANDEIAS, M. M, POWELL, D. J, ROUBALOVA, E, APCHER, S, BOUROUGAA, K, VOJTESEK, B, BRUZZONI-GIOVANELLI, H, FAHRAEUS, R

“…P53 controls the growth and survival of cells by acting in response to a multitude of cellular stresses. It is, however, not yet fully understood how different…”
Get full text

Sirolimus and post transplant Cy synergistically maintain mixed chimerism in a mismatched murine model by Fitzhugh, C D, Weitzel, R P, Hsieh, M M, Phang, O A, Madison, C, Luznik, L, Powell, J D, Tisdale, J F

“…Because of the toxicity associated with myeloablative conditioning, nonmyeloablative regimens are increasingly being used in vulnerable patient populations…”
Get full text

Bacillus anthracis spores germinate extracellularly at air–liquid interface in an in vitro lung model under serum‐free conditions by Powell, J.D., Hutchison, J.R., Hess, B.M., Straub, T.M.

“…Aims To better understand the parameters that govern spore dissemination after lung exposure using in vitro cell systems. Methods and Results We evaluated the…”
Get full text

The RET/PTC3 oncogene : Metastatic solid-type papillary carcinomas in murine thyroids by POWELL, D. J, RUSSELL, J, ROTHSTEIN, J. L, NIBU, K.-I, GUOQI LI, RHEE, E, LIAO, M, GOLDSTEIN, M, KEANE, W. M, SANTORO, M, FUSCO, A

“…Our research goal is to better understand the mechanisms controlling the initiation and progression of thyroid diseases. One such disease, papillary thyroid…”
Get full text

Developments of NEWUOA for minimization without derivatives by Powell, M. J. D.

“…The NEWUOA software is described briefly, with some numerical results that show good efficiency and accuracy in the unconstrained minimization without…”
Get full text

Immunologic recovery following autologous stem-cell transplantation with pre- and posttransplantation rituximab for low-grade or mantle cell lymphoma by Kasamon, Y.L., Jones, R.J., Brodsky, R.A., Fuchs, E.J., Matsui, W., Luznik, L., Powell, J.D., Blackford, A.L., Goodrich, A., Gocke, C.D., Abrams, R.A., Ambinder, R.F., Flinn, I.W.

“…Rituximab may improve transplant outcomes but may delay immunologic recovery. Seventy-seven patients with low-grade or mantle cell lymphoma received autologous…”
Get full text

Using Advancements in Cable-Trapping to Overcome Barriers to Furbearer Management in the United States by VANTASSEL, STEPHEN M., HILLER, TIM L., POWELL, KELLY D. J., HYGNSTROM, SCOTT E.

“…Harvest of furbearers through trapping has been challenged by anti-trapping organizations for centuries, with organizational goals often including prohibition…”
Get full text

Augmenting the Production Operators for Continuous Improvement by Arica, E., Oliveira, M. F., Powell, D. J.

“…This paper discusses how continuous improvement activities can be supported by augmenting the operators in production. After a brief literature background,…”
Get full text

Salvage transplantation for allograft failure using fludarabine and alemtuzumab as conditioning regimen by Bolaños-Meade, J, Luznik, L, Muth, M, Matsui, W H, Huff, C A, Smith, B D, Levy, M Y, Kasamon, Y L, Swinnen, L J, Powell, J D, Brodsky, R A, Ambinder, R F, Jones, R J, Fuchs, E J

“…Graft failure after allogeneic blood or marrow transplantation, although generally uncommon, can be a devastating complication. This report includes the…”
Get full text

Perceptions of Risk and Adaptive Capacity Frame Decisions by Namibians Engaged in Ecotourism by Powell, Larkin A, Powell, Kelly D. J

“…Ecotourism must address financial, ecological, and social expectations to be sustainable as a business venture. Therefore, decisions made by ecotourism…”
Get full text

Geography of Ecotourism Potential in the Great Plains: Incentives for Conservation by Powell, Larkin A., Edwards, Richard, Powell, Kelly D. J., Nieland, Katie

“…Ecotourism on private lands may be an incentive for conservation because of potential profits to landowners. Conservation planners in southern Africa have…”
Get full text

Influence of chick hatch time and access to feed on broiler muscle development by Powell, D. J., Velleman, S. G., Cowieson, A. J., Singh, M., Muir, W. I.

“…The effect of hatch time and the timing of access to feed on growth rate and breast muscle development was assessed in Ross 308 broiler chickens. Chicks were…”
Get full text

ASP1 (BACE2) Cleaves the Amyloid Precursor Protein at the β-Secretase Site by Hussain, I., Powell, D.J., Howlett, D.R., Chapman, G.A., Gilmour, L., Murdock, P.R., Tew, D.G., Meek, T.D., Chapman, C., Schneider, K., Ratcliffe, S.J., Tattersall, D., Testa, T.T., Southan, C., Ryan, D.M., Simmons, D.L., Walsh, F.S., Dingwall, C., Christie, G.

“…Sequential proteolytic processing of the Amyloid Precursor Protein (APP) by β- and γ-secretases generates the 4-kDa amyloid (Aβ) peptide, a key component of…”
Get full text

The effect of nutritional status on myogenic gene expression of satellite cells derived from different muscle types by Powell, D J, McFarland, D C, Cowieson, A J, Muir, W I, Velleman, S G

“…Satellite cells (SC) are a multipotential stem cell population responsible for facilitating posthatch muscle fiber hypertrophy. The proliferation and…”
Get full text

Expression and Localization of Hypoxia-Inducible Factor-1 Subunits in the Adult Rat Epididymis by PALLADINO, M. A, POWELL, J. D, KORAH, N, HERMO, L

“…The epididymal epithelium contributes to formation of a luminal fluid that is essential for the protection of spermatozoa from a variety of insults including…”
Get full text

Influence of hatch time and access to feed on intramuscular adipose tissue deposition in broilers by Powell, D. J., Velleman, S. G., Cowieson, A. J., Singh, M., Muir, W. I.

“…The effect of hatch time and subsequent access to feed on intramuscular adipose tissue deposition was studied in the pectoralis major muscle of male Ross 308…”
Get full text

Adenosine receptors and cancer by Fishman, P, Bar-Yehuda, S, Synowitz, M, Powell, J D, Klotz, K N, Gessi, S, Borea, P A

“…The A(1), A(2A), A(2B) and A(3) G-protein-coupled cell surface adenosine receptors (ARs) are found to be upregulated in various tumor cells. Activation of the…”
Get more information