Search Results - "Powell, Arfon G."

Targeting Wnt Signaling for the Treatment of Gastric Cancer by Koushyar, Sarah, Powell, Arfon G, Vincan, Elizabeth, Phesse, Toby J

“…The Wnt signaling pathway is evolutionarily conserved, regulating both embryonic development and maintaining adult tissue homeostasis. Wnt signaling controls…”
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Evaluation of a tumor microenvironment-based prognostic score in primary operable colorectal cancer by Park, James H, McMillan, Donald C, Powell, Arfon G, Richards, Colin H, Horgan, Paul G, Edwards, Joanne, Roxburgh, Campbell S D

“…The tumor microenvironment is recognized as an important determinant of progression and outcome in colorectal cancer. The aim of the present study was to…”
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The Pretreatment Systemic Inflammatory Response is an Important Determinant of Poor Pathologic Response for Patients Undergoing Neoadjuvant Therapy for Rectal Cancer by Dreyer, Stephan B., Powell, Arfon G. M. T., McSorley, Stephen T., Waterston, Ashita, Going, James J., Edwards, Joanne, McMillan, Donald C., Horgan, Paul G.

“…Background Not all patients respond equally to neoadjuvant chemoradiotherapy (nCRT), with subsequent effects on survival. The systemic inflammatory response…”
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The clinical utility of the local inflammatory response in colorectal cancer by Richards, Colin H, Roxburgh, Campbell S.D, Powell, Arfon G, Foulis, Alan K, Horgan, Paul G, McMillan, Donald C

“…Abstract Background The host immune response is important in the prevention of tumour progression in solid organ cancers. The aim was to evaluate the clinical…”
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The Glasgow Microenvironment Score associates with prognosis and adjuvant chemotherapy response in colorectal cancer by Alexander, Peter G., Roseweir, Antonia K., Pennel, Kathryn A. F., van Wyk, Hester C., Powell, Arfon G. M. T., McMillan, Donald C., Horgan, Paul G., Kelly, Caroline, Hay, Jennifer, Sansom, Owen, Harkin, Andrea, Roxburgh, Campbell S. D., Graham, Janet, Church, David N., Tomlinson, Ian, Saunders, Mark, Iveson, Tim J., Edwards, Joanne, Park, James H.

“…Background The Glasgow Microenvironment Score (GMS) combines peritumoural inflammation and tumour stroma percentage to assess interactions between tumour and…”
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Altmetric Versus Bibliometric Perspective Regarding Publication Impact and Force by Powell, Arfon G. M. T., Bevan, Victoria, Brown, Chris, Lewis, Wyn G.

“…Background Bibliometric and Altmetric analyses highlight key publications, which have been considered to be the most influential in their field. The hypothesis…”
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Prognostic significance of serum inflammatory markers in esophageal cancer by Powell, Arfon G. M. T., Eley, Catherine, Chin, Carven, Coxon, Alexandra H, Christian, Adam, Lewis, Wyn G.

“…Background The aim of this study was to assess the relative prognostic value of biomarkers to measure the systemic inflammatory response (SIR) and potentially…”
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Cardiopulmonary fitness predicts postoperative major morbidity after esophagectomy for patients with cancer by Patel, Neil, Powell, Arfon G., Wheat, Jenni R., Brown, Christopher, Appadurai, Ian R., Davies, Richard G., Bailey, Damian M., Lewis, Wyn G.

“…Surgery for radical treatment of esophageal cancer (EC) carries significant inherent risk. The objective identification of patients who are at high risk of…”
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Correction to: Prognostic significance of serum inflammatory markers in esophageal cancer by Powell, Arfon G. M. T., Eley, Catherine, Chin, Carven, Coxon, Alexandra H., Christian, Adam, Lewis, Wyn G.

“…In the original publication of the article, under the section “Clinicopathological characteristics”, the thresholds…”
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The bodies fight against cancer: is human leucocyte antigen (HLA) class 1 the key? by Powell, Arfon G. M. T., Horgan, Paul G., Edwards, Joanne

“…Introduction Loss of human leucocyte antigen (HLA) class I expression has been implicated in tumour progression and metastasis; however, studies reporting its…”
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Prognostic Significance of Serum Inflammatory Markers in Gastric Cancer by Powell, Arfon G. M. T., Parkinson, Debora, Patel, Neil, Chan, David, Christian, Adam, Lewis, Wyn G.

“…Background The aim of this study was to assess the relative prognostic value of biomarkers to measure the systemic inflammatory response (SIR) and improve…”
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The relationship between genetic profiling, clinicopathological factors and survival in patients undergoing surgery for node-negative colorectal cancer: 10-year follow-up by Powell, Arfon G. M. T., Ferguson, Jenny, Al-Mulla, Fahd, Orange, Clare, McMillan, Donald C., Horgan, Paul G., Edwards, Joanne, Going, James J.

“…Purpose The introduction of the bowel cancer screening programme has resulted in increasing numbers of patients being diagnosed with node-negative disease…”
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To sponge or not to sponge: that is the leak question by Powell, Arfon G., Sultan, Javed

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Mismatch repair status in patients with primary operable colorectal cancer: associations with the local and systemic tumour environment by Park, James H, Powell, Arfon G, Roxburgh, Campbell S D, Horgan, Paul G, McMillan, Donald C, Edwards, Joanne

“…Background: Mismatch repair-deficient (dMMR) colorectal cancer (CRC) is associated with a conspicuous local immune infiltrate; however, its relationship with…”
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Systematic Review and Meta-Analysis of the Prognostic Significance of Neutrophil-Lymphocyte Ratio (NLR) After R0 Gastrectomy for Cancer by Mellor, Katie L, Powell, Arfon G. M. T., Lewis, Wyn G.

“…Purpose A meta-analysis was performed to evaluate the prognostic value of neutrophil-lymphocyte ratio (NLR) in patients undergoing potentially curative…”
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Src family kinases, HCK and FGR, associate with local inflammation and tumour progression in colorectal cancer by Roseweir, Antonia K., Powell, Arfon G.M.T., Horstman, Sheryl L., Inthagard, Jitwadee, Park, James H., McMillan, Donald C., Horgan, Paul G., Edwards, Joanne

“…In colorectal cancer (CRC), inflammatory responses have been reported to associate with patient survival. However, the specific signalling pathways responsible…”
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Biosensors, Biomarkers and Biometrics: a Bootcamp Perspective by James, Osian P, Robinson, David B T, Hopkins, Luke, Bowman, Chris, Powell, Arfon G M T, Brown, Chris, Bailey, Damian M, Egan, Richard J, Lewis, Wyn G

“…IntroductionCompetitive physical performance is routinely monitored by wearable technology (biosensors), yet professional healthcare is not, despite high…”
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Relative Value of Adapted Novel Bibliometrics in Evaluating Surgical Academic Impact and Reach by Robinson, David B. T., Hopkins, Luke, Brown, Chris, Abdelrahman, Tarig, Powell, Arfon G., Egan, Richard J., Lewis, Wyn G.

“…Background The Hirsch index, often used to assess research impact, suffers from questionable validity within the context of General Surgery, and consequently…”
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Team strategic philosophy: requiem for the infinite game by Powell, Arfon G, Bowman, Chris, Brown, Chris, Egan, Richard J, Lewis, Wyn G

“…Five principles are necessary to lead an infinite game: first, a fair basis, such that sacrifices for its advancement are promoted; second, a trusting…”
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Gongs galore: phaleristic study of the relative risk of a healing art related New Year Honour by Mellor, Katie, Powell, Arfon GMT, James, Osian P, Robinson, David B, Hopkins, Luke, Egan, Richard John, Lewis, Wyn G

“…ObjectivesTo compare proportional representation of healthcare specialty workers, in receipt of New Year Honours (NYHs) and examine system…”
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