Search Results - "Powe, D G"

Nottingham Prognostic Index Plus (NPI+): a modern clinical decision making tool in breast cancer by Rakha, E A, Soria, D, Green, A R, Lemetre, C, Powe, D G, Nolan, C C, Garibaldi, J M, Ball, G, Ellis, I O

“…Background: Current management of breast cancer (BC) relies on risk stratification based on well-defined clinicopathologic factors. Global gene expression…”
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Beta-blocker usage after malignant melanoma diagnosis and survival: a population-based nested case-control study by McCourt, C., Coleman, H.G., Murray, L.J., Cantwell, M.M., Dolan, O., Powe, D.G., Cardwell, C.R.

“…Summary Background Beta‐blockers have potential antiangiogenic and antimigratory activity. Studies have demonstrated a survival benefit in patients with…”
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β-Blocker usage and colorectal cancer mortality: a nested case–control study in the UK Clinical Practice Research Datalink cohort by Hicks, B.M., Murray, L.J., Powe, D.G., Hughes, C.M., Cardwell, C.R.

“…Epidemiological and laboratory studies suggest that β-blockers may reduce cancer progression in various cancer sites. The aim of this study was to conduct the…”
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Morphological and immunophenotypic analysis of breast carcinomas with basal and myoepithelial differentiation by Rakha, EA, Putti, TC, Abd El-Rehim, DM, Paish, C, Green, AR, Powe, DG, Lee, AH, Robertson, JF, Ellis, IO

“…The aim of this study was to assess the morphological characteristics and immunohistochemical profile of breast carcinomas with basal and myoepithelial…”
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A gene-expression signature to predict survival in breast cancer across independent data sets by NADERI, A, TESCHENDORFF, A. E, CALDAS, C, BARBOSA-MORAIS, N. L, PINDER, S. E, GREEN, A. R, POWE, D. G, ROBERTSON, J. F. R, APARICIO, S, ELLIS, I. O, BRENTON, J. D

“…Prognostic signatures in breast cancer derived from microarray expression profiling have been reported by two independent groups. These signatures, however,…”
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'Entopy': localized mucosal allergic disease in the absence of systemic responses for atopy by Powe, D. G., Jagger, C., Kleinjan, A., Carney, A. S., Jenkins, D., Jones, N. S.

“…Summary Background The Th2 immune response in the nasal mucosa of subjects with allergic rhinitis is mediated by allergen‐specific IgE. Moreover, these…”
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Alpha- and beta-adrenergic receptor (AR) protein expression is associated with poor clinical outcome in breast cancer: an immunohistochemical study by Powe, D. G., Voss, M. J., Habashy, H. O., Zänker, K. S., Green, A. R., Ellis, I. O., Entschladen, F.

“…Breast cancer mortality is frequently associated with metastatic disease. Metastasis models have shown adrenoceptor (AR) stimulation induces cell migration…”
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'Entopy': local allergy paradigm by Powe, D. G., Bonnin, A. J., Jones, N. S.

“…Summary Cite this as: D. G. Powe, A. J. Bonnin and N. S. Jones, Clinical & Experimental Allergy, 2010 (40) 987–997. Allergy is defined as an immediate…”
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Nottingham prognostic index plus (NPI+) predicts risk of distant metastases in primary breast cancer by Green, Andrew R., Soria, D., Powe, D. G., Nolan, C. C., Aleskandarany, M., Szász, M. A., Tőkés, A. M., Ball, G. R., Garibaldi, J. M., Rakha, E. A., Kulka, J., Ellis, I. O.

“…The Nottingham prognostic index plus (NPI+) is based on the assessment of biological class combined with established clinicopathologic prognostic variables…”
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Identification of key clinical phenotypes of breast cancer using a reduced panel of protein biomarkers by Green, A R, Powe, D G, Rakha, E A, Soria, D, Lemetre, C, Nolan, C C, Barros, F F T, Macmillan, R D, Garibaldi, J M, Ball, G R, Ellis, I O

“…Background: Breast cancer is a heterogeneous disease characterised by complex molecular alterations underlying the varied behaviour and response to therapy…”
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MicroRNA involvement in the pathogenesis and management of breast cancer by Khoshnaw, S M, Green, A R, Powe, D G, Ellis, I O

“…MicroRNAs (miRNAs) are a highly abundant class of endogenous small non-coding RNAs (18-25 nucleotides in length) that regulate gene expression by targeting…”
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proteins FABP7 and OATP2 are associated with the basal phenotype and patient outcome in human breast cancer by Zhang, H, Rakha, E. A, Ball, G. R, Spiteri, I, Aleskandarany, M, Paish, E. C, Powe, D. G, Macmillan, R. D, Caldas, C, Ellis, I. O, Green, A. R

“…The basal-like or basal phenotype (BP) class of breast cancers have recently attracted attention as a poor prognostic form of breast cancer. However, BP…”
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validated gene expression profile for detecting clinical outcome in breast cancer using artificial neural networks by Lancashire, L. J, Powe, D. G, Reis-Filho, J. S, Rakha, E, Lemetre, C, Weigelt, B, Abdel-Fatah, T. M, Green, A. R, Mukta, R, Blamey, R, Paish, E. C, Rees, R. C, Ellis, I. O, Ball, G. R

“…Gene expression microarrays allow for the high throughput analysis of huge numbers of gene transcripts and this technology has been widely applied to the…”
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Atypical nasal challenges in patients with idiopathic rhinitis: more evidence for the existence of allergy in the absence of atopy? by S. Carney, A., Powe, D. G., Huskisson, R. S., Jones, N. S.

“…Summary Background The pathophysiology of idiopathic rhinitis is unknown although evidence is accumulating to suggest that many patients may have a localized…”
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Erratum to: Nottingham prognostic index plus (NPI+) predicts risk of distant metastases in primary breast cancer by Green, Andrew R., Soria, D., Powe, D. G., Nolan, C. C., Aleskandarany, M., Szász, M. A., Tőkés, A. M., Ball, G. R., Garibaldi, J. M., Rakha, E. A., Kulka, J., Ellis, I. O.

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Local mucosal immunoglobulin E production: does allergy exist in non-allergic rhinitis? by Powe, D. G., Jones, N. S.

“…Summary In this review, we critically evaluate the evidence for local IgE production in allergic rhinitis mucosa and the concept of local allergy in non‐atopic…”
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Evidence for an inflammatory pathophysiology in idiopathic rhinitis by Powe, D. G., Huskisson, R. S., Carney, A. S., Jenkins, D., Jones, N. S.

“…Background The pathophysiology of idiopathic rhinitis is unknown but the disease is classified as being non‐allergic on the basis of negative serum IgE…”
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De-regulation of the sonic hedgehog pathway in the InsGas mouse model of gastric carcinogenesis by EI-ZAATARI, M, TOBIAS, A, GRABOWSKA, A. M, KUMARI, R, SCOTTING, P. J, KAYE, P, ATHERTON, J, CLARKE, P. A, POWE, D. G, WATSON, S. A

“…This study investigated sonic hedgehog (Shh) signalling in gastric metaplasia in the insulin-gastrin (InsGas) hypergastrinaemic mouse +/- Helicobacter felis…”
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Mucosal T‐cell phenotypes in persistent atopic and nonatopic rhinitis show an association with mast cells by Powe, D. G., Huskisson, R. S., Carney, A. S., Jenkins, D., McEuen, A. R., Walls, A. F., Jones, N. S.

“…Background:  Allergic rhinitis is characterized by selective expansion of T cell subsets with a CD4+ phenotype. Recently, we identified a subpopulation of…”
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Cytoplasmic PML promotes TGF-β-associated epithelial–mesenchymal transition and invasion in prostate cancer by Buczek, M E, Miles, A K, Green, W, Johnson, C, Boocock, D J, Pockley, A G, Rees, R C, Hulman, G, van Schalkwyk, G, Parkinson, R, Hulman, J, Powe, D G, Regad, T

“…Epithelial–mesenchymal transition (EMT) is a key event that is involved in the invasion and dissemination of cancer cells. Although typically considered as…”
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