Search Results - "Povinelli, Ana Paula Ribeiro"

Details of the cooperative binding of piperlongumine with rat serum albumin obtained by spectroscopic and computational analyses by Povinelli, Ana Paula Ribeiro, Zazeri, Gabriel, de Freitas Lima, Marcelo, Cornélio, Marinônio Lopes

“…Piperlongumine (PPL) has presented a variety of important pharmacological activities. In recent pharmacokinetics studies in rats, this molecule reached 76.39%…”
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Experimental Approaches and Computational Modeling of Rat Serum Albumin and Its Interaction with Piperine by Zazeri, Gabriel, Povinelli, Ana Paula Ribeiro, Lima, Marcelo de Freitas, Cornélio, Marinônio Lopes

“…The bioactive piperine (1-piperoyl piperidine) compound found in some pepper species ( and ) has been shown to have therapeutic properties and to be useful for…”
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The Cytokine IL-1β and Piperine Complex Surveyed by Experimental and Computational Molecular Biophysics by Zazeri, Gabriel, Povinelli, Ana Paula Ribeiro, de Freitas Lima, Marcelo, Cornélio, Marinônio Lopes

“…The bioactive piperine, a compound found in some pepper species, has been widely studied because of its therapeutic properties that include the inhibition of…”
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Experimental studies and computational modeling on cytochrome c reduction by quercetin: The role of oxidability and binding affinity by Zazeri, Gabriel, Povinelli, Ana Paula Ribeiro, Pavan, Nathalia M., de Carvalho, Daniella Romano, Cardoso, Carmen Lúcia, Ximenes, Valdecir Farias

“…•Quercetin is a powerful reducing agent of cytochrome c.•Quercetin has more privileged access to the protoporphyrin prosthetic group.•Over the 35  ns of…”
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Solvent-Induced Lag Phase during the Formation of Lysozyme Amyloid Fibrils Triggered by Sodium Dodecyl Sulfate: Biophysical Experimental and In Silico Study of Solvent Effects by Zazeri, Gabriel, Povinelli, Ana Paula Ribeiro, Pavan, Nathália Mariana, Jones, Alan M, Ximenes, Valdecir Farias

“…Amyloid aggregates arise from either the partial or complete loss of the native protein structure or the inability of proteins to attain their native…”
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A Computational–Experimental Investigation of the Molecular Mechanism of Interleukin-6-Piperine Interaction by Povinelli, Ana Paula Ribeiro, Zazeri, Gabriel, Jones, Alan M., Cornélio, Marinônio Lopes

“…Herein, we elucidate the biophysical aspects of the interaction of an important protein, Interleukin-6 (IL6), which is involved in cytokine storm syndrome,…”
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Enhanced pro-coagulant hemostatic agents based on nanometric zeolites by Laurenti, Juliana Bergamasco, Zazeri, Gabriel, Povinelli, Ana Paula Ribeiro, de Godoy, Moacir Fernandes, Braile, Domingo Marcolino, da Rocha, Tânia R. Flores, D' Amico, Élbio Antônio, Nery, José Geraldo

“…Micro-and nanometric faujasite zeolites were tested as hemostatic coagulant agents. The as-made zeolites and their calcium ion exchanged derivatives were…”
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Unravelling the Interaction of Piperlongumine with the Nucleotide-Binding Domain of HSP70: A Spectroscopic and In Silico Study by Povinelli, Ana Paula Ribeiro, Zazeri, Gabriel, Jones, Alan M, Cornélio, Marinnio Lopes

“…Piperlongumine (PPL) is an alkaloid extracted from several pepper species that exhibits anti-inflammatory and anti-carcinogenic properties. Nevertheless, the…”
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Detailed Characterization of the Cooperative Binding of Piperine with Heat Shock Protein 70 by Molecular Biophysical Approaches by Zazeri, Gabriel, Povinelli, Ana Paula Ribeiro, Lima, Marcelo de Freitas, Cornélio, Marinônio Lopes

“…In this work, for the first time, details of the complex formed by heat shock protein 70 (HSP70) independent nucleotide binding domain (NBD) and piperine were…”
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The Role of Medium Polarity in the Efficiency of Albumin Binding with Hydrophobic Ligands: Experimental Studies and a Molecular Dynamics Investigation by Zazeri, Gabriel, Povinelli, Ana Paula Ribeiro, Bertozo, Luiza de Carvalho, Jones, Alan M., Ximenes, Valdecir Farias

“…This study evaluates how the polarity of the medium affects the binding efficiency of hydrophobic ligands with human serum albumin (HSA). The polarity of the…”
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A flaw in applying the FRET technique to evaluate the distance between ligands and tryptophan residues in human serum albumin: Proposal of correction by Povinelli, Ana Paula Ribeiro, de Carvalho Bertozo, Luiza, Zazeri, Gabriel, Ximenes, Valdecir Farias

“…Due to its primordial function as a drug carrier, human serum albumin (HSA) is extensively studied regarding its binding affinity with developing drugs…”
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4-Dimethylamino-beta-nitrostyrene, a fluorescent solvatochromic probe to estimate the apparent dielectric constant in serum albumin: Experimental and molecular dynamics studies by Fernandes, Ana Julia Foganholi Carvalho, de Carvalho Bertozo, Luiza, Povinelli, Ana Paula Ribeiro, Zazeri, Gabriel, de Souza, Aguinaldo Robinson, Morgon, Nelson Henrique, Ximenes, Valdecir Farias

“…[Display omitted] •4-Dimethylamino-beta-nitrostyrene (DANS) works as a fluorescent solvatochromic probe.•DANS has its fluorescence increased upon binding in…”
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The Cytokine IL-1[beta] and Piperine Complex Surveyed by Experimental and Computational Molecular Biophysics by Zazeri, Gabriel, Povinelli, Ana Paula Ribeiro, Lima, Marcelo de Freitas, Cornelio, Marinonio Lopes

“…The bioactive piperine, a compound found in some pepper species, has been widely studied because of its therapeutic properties that include the inhibition of…”
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