Search Results - "Povilaitis, Sydney C."
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Leaflet-Dependent Effect of Anionic Lipids on Membrane Insertion by Cationic Cell-Penetrating Peptides
Published in The journal of physical chemistry letters (29-06-2023)“…Cationic membrane-permeating peptides can cross membranes unassisted by transmembrane protein machinery, and there is consensus that anionic lipids facilitate…”
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Leaflet dependent effect of anionic phospholipids on the permeation of cell penetrating peptides into model membranes
Published in Biophysical journal (10-02-2023)Get full text
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Design of Peptides for Membrane Insertion: The Critical Role of Charge Separation
Published in The journal of physical chemistry. B (01-09-2022)“…A physical understanding of membrane permeation and translocation by small, positively charged molecules can illuminate cell penetrating peptide mechanisms of…”
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Identifying Clinically Relevant Bacteria Directly from Culture and Clinical Samples with a Handheld Mass Spectrometry Probe
Published in Clinical chemistry (Baltimore, Md.) (03-11-2022)“…Rapid identification of bacteria is critical to prevent antimicrobial resistance and ensure positive patient outcomes. We have developed the MasSpec Pen, a…”
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Visualization of Molecular Permeation into a Multi-compartment Phospholipid Vesicle
Published in The journal of physical chemistry letters (20-07-2023)“…Passive permeation of small molecules into vesicles with multiple compartments is a critical event in many chemical and biological processes. We consider the…”
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Clinical Translation and Evaluation of a Handheld and Biocompatible Mass Spectrometry Probe for Surgical Use
Published in Clinical chemistry (Baltimore, Md.) (01-09-2021)“…Intraoperative tissue analysis and identification are critical to guide surgical procedures and improve patient outcomes. Here, we describe the clinical…”
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Rapid Screening of COVID-19 Directly from Clinical Nasopharyngeal Swabs Using the MasSpec Pen
Published in Analytical chemistry (Washington) (21-09-2021)“…The outbreak of COVID-19 has created an unprecedent global crisis. While the polymerase chain reaction (PCR) is the gold standard method for detecting active…”
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Noninvasive Detection of Chemical Defenses in Poison Frogs Using the MasSpec Pen
Published in ACS measurement science au (19-10-2022)“…Poison frogs are well-known for their fascinating ability to store alkaloids in their skin as chemical defense against predators. Chemical methods used to…”
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662. Identification of Clinically Relevant Microbes with the MasSpec Pen
Published in Open forum infectious diseases (31-12-2020)Get full text
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