Search Results - "Povedano, Mónica"
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Elevated Cerebrospinal Fluid Proteins and Albumin Determine a Poor Prognosis for Spinal Amyotrophic Lateral Sclerosis
Published in International journal of molecular sciences (01-10-2022)“…Amyotrophic lateral sclerosis (ALS) is a heterogeneous disease, both in its onset phenotype and in its rate of progression. The aim of this study was to…”
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2
The increasing importance of environmental conditions in amyotrophic lateral sclerosis
Published in International journal of biometeorology (01-08-2018)“…Amyotrophic lateral sclerosis (ALS) is the most common neurodegenerative disease affecting motor neurons (MNs). Although a small percentage of ALS has a…”
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3
Microvascular abnormalities in skin capillaries of individuals with amyotrophic lateral sclerosis
Published in Scientific reports (20-10-2024)“…This is the first study aimed to detect morphological abnormalities in vivo in the skin capillaries of amyotrophic lateral sclerosis patients (ALS)…”
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4
Amyotrophic lateral sclerosis, gene deregulation in the anterior horn of the spinal cord and frontal cortex area 8: implications in frontotemporal lobar degeneration
Published in Aging (Albany, NY.) (09-03-2017)“…Transcriptome arrays identifies 747 genes differentially expressed in the anterior horn of the spinal cord and 2,300 genes differentially expressed in frontal…”
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5
Complex Inflammation mRNA-Related Response in ALS Is Region Dependent
Published in Neural plasticity (01-01-2015)“…Inflammatory changes are analyzed in the anterior spinal cord and frontal cortex area 8 in typical spinal-predominant ALS cases. Increased numbers of…”
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6
Administration of Riluzole Oral Suspension During the Different Stages of Amyotrophic Lateral Sclerosis
Published in Frontiers in neurology (08-07-2021)“…Amyotrophic Lateral Sclerosis (ALS) is a fatal adult-onset neurodegenerative disorder that affects the upper and/or lower motor neurons and is associated with…”
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7
Inflammatory Gene Expression in Whole Peripheral Blood at Early Stages of Sporadic Amyotrophic Lateral Sclerosis
Published in Frontiers in neurology (13-10-2017)“…Characterization of altered expression of selected transcripts linked to inflammation in the peripheral blood of sporadic amyotrophic lateral sclerosis (sALS)…”
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8
Intermediate Repeat Expansion in the ATXN2 Gene as a Risk Factor in the ALS and FTD Spanish Population
Published in Biomedicines (02-02-2024)“…Intermediate CAG expansions in the gene ataxin-2 ( ) are a known risk factor for ALS, but little is known about their role in FTD risk. Moreover, their…”
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9
La gastrostomía percutánea como procedimiento para mejorar la supervivencia de los pacientes con esclerosis lateral amiotrófica
Published in Atención primaria (01-05-2022)Get full text
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La esclerosis lateral amiotrófica (ELA) desde la Atención Primaria. Epidemiología y características clínico-asistenciales
Published in Atención primaria (01-12-2021)“…La ELA es una enfermedad poco frecuente en atención primaria (AP), representa un desafío para el médico de familia especialmente en atención domiciliaria…”
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11
Detecting Bulbar Involvement in Patients with Amyotrophic Lateral Sclerosis Based on Phonatory and Time-Frequency Features
Published in Sensors (Basel, Switzerland) (01-02-2022)“…The term "bulbar involvement" is employed in ALS to refer to deterioration of motor neurons within the corticobulbar area of the brainstem, which results in…”
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12
TDP-43 Vasculopathy in the Spinal Cord in Sporadic Amyotrophic Lateral Sclerosis (sALS) and Frontal Cortex in sALS/FTLD-TDP
Published in Journal of neuropathology and experimental neurology (01-03-2021)“…Abstract Sporadic amyotrophic lateral sclerosis (sALS) and FTLD-TDP are neurodegenerative diseases within the spectrum of TDP-43 proteinopathies. Since…”
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13
Estimation of the prevalence and incidence of motor neuron diseases in two Spanish regions: Catalonia and Valencia
Published in Scientific reports (18-03-2021)“…According to the degree of upper and lower motor neuron degeneration, motor neuron diseases (MND) can be categorized into amyotrophic lateral sclerosis (ALS),…”
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14
Voiceprint and machine learning models for early detection of bulbar dysfunction in ALS
Published in Computer methods and programs in biomedicine (01-02-2023)“…•Objective approaches are needed to diagnose bulbar involvement in ALS patients.•The proposed voiceprint may lead to the development of a cheap and easy-to-use…”
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15
Large-scale analyses of CAV1 and CAV2 suggest their expression is higher in post-mortem ALS brain tissue and affects survival
Published in Frontiers in cellular neuroscience (02-03-2023)“…Caveolin-1 and Caveolin-2 (CAV1 and CAV2) are proteins associated with intercellular neurotrophic signalling. There is converging evidence that CAV1 and CAV2…”
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16
Examining the complex Interplay between gut microbiota abundance and short-chain fatty acid production in amyotrophic lateral sclerosis patients shortly after onset of disease
Published in Scientific reports (08-10-2024)“…This study aimed to assess differences in the enteral microbiome of relatively recent-onset amyotrophic lateral sclerosis (ALS) patients (< 6–15 months since…”
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17
Gene Expression Profile in Frontal Cortex in Sporadic Frontotemporal Lobar Degeneration-TDP
Published in Journal of neuropathology and experimental neurology (01-07-2018)“…Abstract Molecular alterations compromising key metabolic pathways are poorly understood in sporadic frontotemporal lobar degeneration with TDP-43 pathology…”
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18
Laser evoked potentials in the evaluation of hypoesthetic patches in tuberculoid leprosy
Published in Clinical neurophysiology (01-02-2021)Get full text
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19
Neurodegeneration Biomarkers in Adult Spinal Muscular Atrophy (SMA) Patients Treated with Nusinersen
Published in International journal of molecular sciences (01-04-2024)“…The objective of this study is to evaluate biomarkers for neurodegenerative disorders in adult SMA patients and their potential for monitoring the response to…”
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Amyotrophic lateral sclerosis (ALS) from the perspective of Primary Care. Epidemiology and clinical-care characteristics
Published in Atención primaria (01-12-2021)“…Amyotrophic Lateral Sclerosis (ALS) is a rare disease in primary care (PC), it represents a challenge for the family doctor, especially in home care. To know…”
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