Search Results - "Poveda, L"
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Defining well-being in psoriasis: A Delphi consensus among healthcare professionals and patients
Published in Scientific reports (24-06-2024)“…Psoriasis is a chronic skin disease that negatively impacts on patient’s life. A holistic approach integrating well-being assessment could improve disease…”
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Expression of Non-T Cell Activation Linker (NTAL) in Jurkat Cells Negatively Regulates TCR Signaling: Potential Role in Rheumatoid Arthritis
Published in International journal of molecular sciences (26-02-2023)“…T lymphocytes are key players in adaptive immune responses through the recognition of peptide antigens through the T Cell Receptor (TCR). After TCR engagement,…”
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Onasemnogene Abeparvovec Administration via Peripherally Inserted Central Catheter: A Case Report
Published in Children (Basel) (01-05-2024)“…Onasemnogene abeparvovec (OA) is the approved intravenous gene therapy for the treatment of spinal muscular atrophy (SMA). A functional copy of the human gene…”
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Real-world analysis of the PK-guided switch from standard half-life factor VIII to efmoroctocog alfa
Published in Thrombosis research (01-01-2024)Get full text
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The β2-adrenergic receptor antagonist ICI-118,551 blocks the constitutively activated HIF signalling in hemangioblastomas from von Hippel-Lindau disease
Published in Scientific reports (11-07-2019)“…One of the major consequences of the lack of a functional VHL protein in von Hippel-Lindau disease, a rare cancer, is the constitutive activation of the HIF…”
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Hospitalization budget impact during the COVID-19 pandemic in Spain
Published in Health economics review (03-11-2021)“…Objectives: The aim was to determine the direct impact of the COVID-19 pandemic on Spain's health budget. Methods: Budget impact analyses based on…”
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Experimental and Theoretical Studies on Arene-Bridged Metal-Metal-Bonded Dimolybdenum Complexes
Published in Chemistry : a European journal (12-05-2014)“…The bis(hydride) dimolybdenum complex, [Mo2(H)2{HC(N‐2,6‐iPr2C6H3)2}2(thf)2], 2, which possesses a quadruply bonded Mo2II core, undergoes light‐induced (365…”
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Iridium(III)-Induced Isomerization of 2-Substituted Pyridines to N-Heterocyclic Carbenes
Published in Journal of the American Chemical Society (11-10-2006)“…Steric strains (F-strain or front-strain) in the acid−base interaction between the Lewis acid [TpMe2Ir(C6H5)2] and 2-substituted pyridines Lewis bases, are…”
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Pilot evaluation of home delivery programme in haemophilia
Published in Journal of clinical pharmacy and therapeutics (01-12-2018)“…Summary What is known and objectives Most of the clotting factor (CF) dispensations to haemophiliac patients are centralized in a few haemophilia treatment…”
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Monodentate, N-Heterocyclic Carbene-Type Coordination of 2,2'-Bipyridine and 1,10-Phenanthroline to Iridium
Published in Angewandte Chemie (International ed.) (26-05-2008)“…Unusual Carbenes: 2,2′‐Bipyridine and 1,10‐phenanthroline are capable of coordinating to iridium as monodentate N‐heterocyclic carbene ligands stabilized by…”
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Formation of Unusual Iridabenzene and Metallanaphthalene Containing Electron-Withdrawing Substituents
Published in Journal of the American Chemical Society (20-08-2003)“…A new route to irida-aromatic derivatives which consists of the oxidation of bicyclic compounds has been disclosed. The iridanaphthalene 3 experiences…”
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Tautomerisation of 2-Substituted Pyridines to N-Heterocyclic Carbene Ligands Induced by the 16 e− Unsaturated [TpMe2IrIII(C6H5)2] Moiety
Published in Chemistry : a European journal (10-04-2012)“…The complex [TpMe2Ir(C6H5)2(N2)] reacts with several 2‐substituted pyridines to generate N‐heterocyclic carbenes resulting from a formal 1,2‐hydrogen shift…”
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Reactivity Studies of Iridium Pyridylidenes [TpMe2Ir(C6H5)2(C(CH)3C(R)NH] (R=H, Me, Ph)
Published in Chemistry : a European journal (18-03-2013)“…The reactivity of a series of iridiumpyridylidene complexes with the formula [TpMe2Ir(C6H5)2(C(CH)3C(R)NH] (1 a–1 c) towards a variety of substrates, from…”
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14
Non‐T cell activation linker (NTAL) proteolytic cleavage as a terminator of activatory intracellular signals
Published in Journal of leukocyte biology (01-08-2016)“…Fas‐induced NTAL proteolytic cleavage acts as a terminator mechanism of immune receptors associated intracellular signals. Non‐T cell activation linker is an…”
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Rearrangement of Pyridine to Its 2-Carbene Tautomer Mediated by Iridium
Published in Journal of the American Chemical Society (21-11-2007)“…One of the Ir−CH2 bonds within the chelate structure of compound 1 acts as a C−H activation shuttle and permits the 1,2-H shift needed for the isomerization of…”
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Impact of novel polymorphisms related to cytotoxicity of cytarabine in the induction treatment of acute myeloid leukemia
Published in Pharmacogenetics and genomics (01-07-2017)“…Several novel single nucleotide polymorphisms (SNPs) involved in cytarabine cytotoxicity and related to clinical outcomes have been reported recently in a…”
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Decarbonylation of Aliphatic Aldehydes by a TpMe2Ir(III) Metallacyclopentadiene
Published in Organometallics (23-01-2012)“…The Ir(III) compound TpMe2 Ir[C(CO2Me)C(CO2Me)C(CO2Me)C(CO2Me)](OH2) (1) reacts thermally with aliphatic aldehydes RC(O)H (R = Me, t Bu) to lead to the…”
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Association of SNPs with the efficacy and safety of immunosuppressant therapy after heart transplantation
Published in Pharmacogenomics (01-06-2015)“…Studying the possible influence of SNPs on efficacy and safety of calcineurin inhibitors upon heart transplantation. In 60 heart transplant patients treated…”
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Meta-analysis and systematic review of the effect of the donor and recipient CYP3A5 6986A>G genotype on tacrolimus dose requirements in liver transplantation
Published in Pharmacogenetics and genomics (01-10-2013)“…OBJECTIVEA meta-analysis was carried out of published studies on the effect of the CYP3A5 6986A>G polymorphism in liver donors and transplant recipients on…”
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Haemodialysis significantly reduces serum levetiracetam levels inducing epileptic seizures: Case report
Published in Journal of clinical pharmacy and therapeutics (01-12-2017)“…Summary What is known and objective Levetiracetam is used in the treatment of some forms of epilepsy. In renal impairment and patients on chronic…”
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