Search Results - "Pouw, Nadine"

Effects of dapagliflozin on postprandial lipid metabolism in type 2 diabetes mellitus by Burggraaf, Benjamin, Pouw, Nadine M C, Fernández Arroyo, Salvador, van Vark-van der Zee, Leonie C, van de Geijn, Gert-Jan M, Birnie, Erwin, Huisbrink, Jeannine, van der Zwan, Ellen M, de Herder, Wouter W, Mulder, Monique T, Rensen, Patrick C N, Castro Cabezas, Manuel

“…Objectives Sodium-glucose cotransporter 2 inhibitors (SGLT2i) modulate lipid metabolism and improve cardiovascular morbidity and mortality in patients with…”
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A placebo‐controlled proof‐of‐concept study of alirocumab on postprandial lipids and vascular elasticity in insulin‐treated patients with type 2 diabetes mellitus by Burggraaf, Benjamin, Pouw, Nadine M.C., Arroyo, Salvador Fernández, Vark‐van der Zee, Leonie C., Geijn, Gert‐Jan M., Birnie, Erwin, Huisbrink, Jeannine, Zwan, Ellen M., Mulder, Monique T., Rensen, Patrick C.N., Herder, Wouter W., Cabezas, Manuel Castro

“…Aim Type 2 diabetes mellitus (T2DM) is associated with an increased risk of cardiovascular disease (CVD) linked to atherogenic dyslipidaemia and postprandial…”
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The alternative Thomas‐plot: A new tool for effective anemia diagnostics by Leur, Kitty, Pouw, Nadine M. C., Lopez, Jordy, Waals‐Prinzen, Lenneke, Ceelie, Huib, Zwan‐van Beek, Ellen M.

“…Introduction The Thomas‐plot has proven to be a helpful tool to discriminate between different types of anemia. This plot combines the reticulocyte hemoglobin…”
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Effect of Vitamin D3 on the Postprandial Lipid Profile in Obese Patients: A Non-Targeted Lipidomics Study by Fernández-Arroyo, Salvador, Hernández-Aguilera, Anna, de Vries, Marijke A., Burggraaf, Benjamin, van der Zwan, Ellen, Pouw, Nadine, Joven, Jorge, Castro Cabezas, Manuel

“…Postprandial lipemia can lead to an accumulation of atherogenic lipoproteins in the circulation associated with systemic low-grade inflammation and an…”
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Analyses of abdominal adiposity and metabolic syndrome as risk factors for respiratory distress in COVID-19 by van Zelst, Cathelijne M, Janssen, Matthijs L, Pouw, Nadine, Birnie, Erwin, Castro Cabezas, Manuel, Braunstahl, Gert-Jan

“…BackgroundSeveral characteristics of the metabolic syndrome, such as obesity and hypertension, have emerged as risk factors for a poor clinical outcome in…”
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Subclinical cardiac dysfunction in obesity patients is linked to autonomic dysfunction: findings from the CARDIOBESE study by Snelder, Sanne M., Groot‐de Laat, Lotte E., Biter, L. Ulas, Castro Cabezas, Manuel, Pouw, Nadine, Birnie, Erwin, Boxma‐de Klerk, Bianca M., Klaassen, René A., Zijlstra, Felix, Dalen, Bas M.

“…Aims Obesity doubles the lifetime risk of developing heart failure. Current knowledge on the role of obesity in causing cardiac dysfunction is insufficient for…”
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Cardiovascular Biomarker Profiles in Obesity and Relation to Normalization of Subclinical Cardiac Dysfunction after Bariatric Surgery by Snelder, Sanne M, Pouw, Nadine, Aga, Yaar, Castro Cabezas, Manuel, Biter, L Ulas, Zijlstra, Felix, Kardys, Isabella, van Dalen, Bas M

“…We aimed to gain insight into the underlying pathophysiology of cardiac dysfunction in obesity patients and the improvement of cardiac function after weight…”
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Gene transfer of human TCR in primary murine T cells is improved by pseudo-typing with amphotropic and ecotropic envelopes by Pouw, Nadine M. C., Westerlaken, Elike J., Willemsen, Ralph A., Debets, Reno

“…Background T cell receptor (TCR) gene therapy represents an attractive anti‐cancer treatment but requires further optimization of its efficacy and safety in…”
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Clinically Relevant Laboratory Monitoring of Gender-Affirming Hormone Therapy in Transgender People-Experiences from a Teaching Hospital in the Netherlands by Pouw, Nadine, van der Linden, Joke, Teuben, Sonja, Kos, Snježana

“…Transgender care is shifting from academic to nonacademic settings leading to use of common (immunoassay) compared to sophisticated (mass spectrometry) methods…”
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Lethal graft-versus-host disease in mouse models of T cell receptor gene therapy by de Witte, Moniek A, Uckert, Wolfgang, Song, Ji-Ying, Linnemann, Carsten, Haanen, John B A G, Bendle, Gavin M, Schumacher, Ton N M, Pouw, Nadine, Kaiser, Andrew D M, Hooijkaas, Anna I, Bies, Laura, Jorritsma, Annelies, Debets, Reno, Kieback, Elisa

“…T cell receptor (TCR) gene therapy is a promising immunotherapy for cancer and infectious disease. But introducing exogenous TCR α and β chains into T cells…”
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Adult but not childhood onset asthma is associated with the metabolic syndrome, independent from body mass index by de Boer, Geertje M., Tramper-Stranders, Gerdien A., Houweling, Laura, van Zelst, Cathelijne M., Pouw, Nadine, Verhoeven, Gert T., Boxma-de Klerk, Bianca M., in ’t Veen, Johannes C.C.M., van Rossum, Elisabeth F.C., Hendriks, Rudi W., Braunstahl, Gert-Jan

“…Adult-onset asthma (AOA) is usually more severe compared to childhood onset asthma (CoA). Given the increasing evidence that AoA is associated with obesity, we…”
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Normalization of Cardiac Function After Bariatric Surgery Is Related to Autonomic Function and Vitamin D by Snelder, Sanne M., Aga, Yaar, de Groot - de Laat, Lotte E., Biter, L. Ulas, Cabezas, Manuel Castro, Pouw, Nadine, Birnie, Erwin, Boxma - de Klerk, Bianca, Klaassen, René A., Zijlstra, Felix, van Dalen, Bas M.

“…Purpose Subclinical cardiac dysfunction is common in patients with obesity. Bariatric surgery is associated with normalization of subclinical cardiac function…”
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Cardiac Function Normalizes 1 Year After Bariatric Surgery in Half of the Obesity Patients with Subclinical Cardiac Dysfunction by Snelder, Sanne M., Aga, Yaar, de Groot-de Laat, Lotte E., Biter, L. Ulas, Castro Cabezas, Manuel, Pouw, Nadine, Boxma - de Klerk, Bianca M., Klaassen, René A., Zijlstra, Felix, van Dalen, Bas M.

“…Graphical abstract…”
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Biomarker profiles in obesity patients and their relation to cardiac dysfunction by Snelder, Sanne M, Pouw, Nadine, Aga, Yaar, Cabezas, Manuel C, Zijlstra, Felix, Kardys, Isabella, van Dalen, Bas M

“…Current knowledge on the role of obesity in causing cardiac dysfunction is insufficient. Several biomarkers reflecting biological processes that may play a…”
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Effect of Vitamin D 3 on the Postprandial Lipid Profile in Obese Patients: A Non-Targeted Lipidomics Study by Fernández-Arroyo, Salvador, Hernández-Aguilera, Anna, de Vries, Marijke A, Burggraaf, Benjamin, van der Zwan, Ellen, Pouw, Nadine, Joven, Jorge, Cabezas, Manuel Castro

“…: Postprandial lipemia can lead to an accumulation of atherogenic lipoproteins in the circulation associated with systemic low-grade inflammation and an…”
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Combination of IL-21 and IL-15 enhances tumour-specific cytotoxicity and cytokine production of TCR-transduced primary T cells by Pouw, Nadine, Treffers-Westerlaken, Elike, Kraan, Jaco, Wittink, Floyd, ten Hagen, Timo, Verweij, Jaap, Debets, Reno

“…IL-21, and to a lesser extent IL-15, inhibits differentiation of antigen-primed CD8 T cells and promotes their homeostasis and anti-tumour activity. Here, we…”
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Human Microtumors Generated in 3D: Novel Tools for Integrated In Situ Studies of Cancer Immunotherapies by Hambach, Lothar, Buser, Andreas, Vermeij, Marcel, Pouw, Nadine, van der Kwast, Theo, Goulmy, Els

“…Cellular immunotherapy targeting human tumor antigens is a promising strategy to treat solid tumors. Yet clinical results of cellular immunotherapy are…”
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Assessment of Comorbidity in Bariatric Patients through a Biomarker-Based Model-A Multicenter Validation of the Metabolic Health Index by Gensen, Carmen, van Loon, Saskia L M, van Riel, Natal A, Nienhuijs, Simon, Triepels, Ralf, Kos, Snježana, Mulder, Alide H L, Pouw, Nadine, Scharnhorst, Volkher, Boer, Arjen-Kars

“…The metabolic health index (MHI) is a biomarker-based model that objectively assesses the cumulative impact of comorbidities type 2 diabetes mellitus,…”
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TCR gene-engineered T cell: Limited T cell activation and combined use of IL-15 and IL-21 ensure minimal differentiation and maximal antigen-specificity by Pouw, Nadine, Treffers-Westerlaken, Elike, Mondino, Anna, Lamers, Cor, Debets, Reno

“…Clinical TCR gene therapy of melanoma represents a feasible and promising treatment rationale yet is currently challenged by objective response rates that stay…”
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