Search Results - "Poustforoosh, Alireza"

Modeling and affinity maturation of an anti-CD20 nanobody: a comprehensive in-silico investigation by Poustforoosh, Alireza, Faramarz, Sanaz, Negahdaripour, Manica, Hashemipour, Hassan

“…B-cell Non-Hodgkin lymphomas are the malignancies of lymphocytes. CD20 is a membrane protein, which is highly expressed on the cell surface of the B-cells in…”
Get full text

Conventional agrochemicals towards nano-biopesticides: an overview on recent advances by Abdollahdokht, Danial, Gao, Yunhao, Faramarz, Sanaz, Poustforoosh, Alireza, Abbasi, Mojtaba, Asadikaram, Gholamreza, Nematollahi, Mohammad Hadi

“…Pesticides are classified into several groups based on their structure, including fungicides, insecticides, herbicides, bactericides, and rodenticides…”
Get full text

Preparation of nano‐micelles of meloxicam for transdermal drug delivery and simulation of drug release: A computational supported experimental study by Poustforoosh, Alireza, Hashemipour, Hassan, Pardakhty, Abbas, Pour, Maryam Kalantari

“…Meloxicam (MLX) is a generic drug with a wide range of pharmaceutical applications in the world. In this study, the nanostructural form of MLX was prepared…”
Get full text

The Impact of D614G Mutation of SARS-COV-2 on the Efficacy of Anti-viral Drugs: A Comparative Molecular Docking and Molecular Dynamics Study by Poustforoosh, Alireza, Hashemipour, Hassan, Tüzün, Burak, Azadpour, Mahdiyeh, Faramarz, Sanaz, Pardakhty, Abbas, Mehrabani, Mehrnaz, Nematollahi, Mohammad Hadi

“…D614G is one of the most reported mutations in the spike protein of SARS-COV-2 that has altered some crucial characteristics of coronaviruses, such as rate of…”
Get full text

In silico SELEX screening and statistical analysis of newly designed 5mer peptide-aptamers as Bcl-xl inhibitors using the Taguchi method by Poustforoosh, Alireza, Faramarz, Sanaz, Nematollahi, Mohammad Hadi, Hashemipour, Hassan, Negahdaripour, Manica, Pardakhty, Abbas

“…Drug development for cancer treatment is a complex process that requires special efforts. Targeting crucial proteins is the most essential purpose of drug…”
Get full text

Construction of Bio-conjugated nano-vesicles using non-ionic surfactants for targeted drug delivery: A computational supported experimental study by Poustforoosh, Alireza, Farmarz, Sanaz, Nematollahi, Mohammad Hadi, Hashemipour, Hassan, Pardakhty, Abbas

“…[Display omitted] •The binding affinity of various biomolecules to their related transporters was evaluated using computational approaches.•The appropriate…”
Get full text

Comparison of Protective Effects of Phenolic Acids on Protein Glycation of BSA Supported by In Vitro and Docking Studies by Rashedinia, Marzieh, Rasti Arbabi, Zeinab, Sabet, Razieh, Emami, Leila, Poustforoosh, Alireza, Sabahi, Zahra

“…Several diabetic complications are associated with forming advanced glycation end products (AGEs). Different chemical and natural compounds are able to prevent…”
Get full text

Synthesis, biological evaluation, molecular docking, MD simulation and DFT analysis of new 3-hydroxypyridine-4-one derivatives as anti-tyrosinase and antioxidant agents by Sadeghian, Sara, Zare, Fateme, Khoshneviszadeh, Mehdi, Hafshejani, Arian Fathi, Salahshour, Farhang, Khodabakhshloo, Ahmadreza, Saghaie, Lotfollah, Goshtasbi, Ghazal, Sarikhani, Zahra, Poustforoosh, Alireza, Sabet, Razieh, Sadeghpour, Hossein

“…In the present study, ten new substituted 3-hydroxypyridine-4-one derivatives were synthesized in a four-step method, and their chemical structures were…”
Get full text

Investigation on the structural and dynamical properties of cationic, anionic, and catanionic niosomes as multifunctional controlled drug delivery system for cabozantinib by Poustforoosh, Alireza

“…Niosomes are versatile nanocarriers for therapeutic compounds, and optimizing their structures via ionic surfactants can enhance their functionality…”
Get full text

Synthesis and cytotoxic activity evaluation of novel imidazopyridine carbohydrazide derivatives by Firouzi, Maryam, Haghighijoo, Zahra, Eskandari, Masoomeh, Mohabbati, Maryam, Miri, Ramin, Jamei, Mohammad Hasan, Poustforoosh, Alireza, Nazari, Somayeh, Firuzi, Omidreza, Khoshneviszadeh, Mehdi, Edraki, Najmeh

“…Two series of novel imidazo[1,2-a]pyridine-2-carbohydrazide derivatives have been designed, synthesized, and evaluated for cytotoxic activity. Target compounds…”
Get full text

Scaffold Hopping Method for Design and Development of Potential Allosteric AKT Inhibitors by Poustforoosh, Alireza

“…Targeting AKT is a practical strategy for cancer therapy in many cancer types. Targeted inhibitors of AKT are attractive solutions for inhibiting the…”
Get full text

The impact of cationic/anionic ratio on the physicochemical aspects of catanionic niosomes as a promising carrier for anticancer drugs by Poustforoosh, Alireza

“…[Display omitted] •Catanionic niosomes, composed of cationic and anionic surfactants, are multifunctional carriers for anticancer drugs.•CTAB and SDS were…”
Get full text

Evaluation of the Cytotoxicity, Antibacterial, Antioxidant, and Anti-inflammatory Effects of Different Extracts of Punica granatum var. pleniflora by Mehrnaz Mehrabani, Mahboobeh Raeiszadeh, Hamid Najafipour, Mojde Esmaeli Tarzi, Arian Amirkhosravi, Alireza Poustforoosh, Mohammad Ali Mohammadi, Sara Naghdi, Mitra Mehrabani

“…Background:Punica granatum var. pleniflora (PGP) has been used for thousands of years as an effective agent to treat various types of diseases. However, there…”
Get full text

Evaluation of the FDA-approved kinase inhibitors to uncover the potential repurposing candidates targeting ABC transporters in multidrug-resistant cancer cells: an in silico approach by Poustforoosh, Alireza, Moosavi, Fatemeh

“…Multiple drug resistance (MDR) is characterized by the resistance of cancer cells to a broad spectrum of anticancer drugs. The main mechanism underlying the…”
Get full text

Recent advances in Bio-conjugated nanocarriers for crossing the Blood-Brain Barrier in (pre-)clinical studies with an emphasis on vesicles by Poustforoosh, Alireza, Nematollahi, Mohammad Hadi, Hashemipour, Hassan, Pardakhty, Abbas

“…The brain is one of the most challenging organs for drug delivery. It is preserved by the blood-brain barrier (BBB), which controls the transport of components…”
Get full text

Evaluation of potential anti-RNA-dependent RNA polymerase (RdRP) drugs against the newly emerged model of COVID-19 RdRP using computational methods by Poustforoosh, Alireza, Hashemipour, Hassan, Tüzün, Burak, Pardakhty, Abbas, Mehrabani, Mehrnaz, Nematollahi, Mohammad Hadi

“…Despite all the efforts to treat COVID-19, no particular cure has been found for this virus. Since developing antiviral drugs is a time-consuming process, the…”
Get full text

3D‐QSAR, molecular docking, molecular dynamics, and ADME/T analysis of marketed and newly designed flavonoids as inhibitors of Bcl‐2 family proteins for targeting U‐87 glioblastoma by Poustforoosh, Alireza, Faramarz, Sanaz, Nematollahi, Mohammad Hadi, Hashemipour, Hassan, Tüzün, Burak, Pardakhty, Abbas, Mehrabani, Mehrnaz

“…Glioblastoma is the most common and destructive brain tumor with increasing complexity. Flavonoids are versatile natural compounds with the approved anticancer…”
Get full text

Niosomal virosome derived by vesicular stomatitis virus glycoprotein as a new gene carrier by Asadikaram, Gholamreza, Poustforoosh, Alireza, Pardakhty, Abbas, Torkzadeh-Mahani, Masoud, Nematollahi, Mohammad Hadi

“…Virosomes as membranous vesicles with viral fusion protein in their membrane are versatile vehicles for cargo delivery. The vesicular stomatitis virus…”
Get full text

Tracing the pathways and mechanisms involved in the anti-breast cancer activity of glycyrrhizin using bioinformatics tools and computational methods by Poustforoosh, Alireza, Faramarz, Sanaz, Negahdaripour, Manica, Tüzün, Burak, Hashemipour, Hassan

“…A complete investigation to understand the pathways that could be affected by glycyrrhizin (licorice), as anti-breast cancer (BC) agent, has not been performed…”
Get full text

Foretinib, a c-MET receptor tyrosine kinase inhibitor, tackles multidrug resistance in cancer cells by inhibiting ABCB1 and ABCG2 transporters by Nazari, Somayeh, Mosaffa, Fatemeh, Poustforoosh, Alireza, Mortazavi, Motahareh, Saso, Luciano, Firuzi, Omidreza, Moosavi, Fatemeh

“…ABC transporter-mediated multidrug resistance (MDR) remains a major obstacle for cancer pharmacological treatment. Some tyrosine kinase inhibitors (TKIs) have…”
Get full text