Search Results - "Pousse, Laurène"
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T Cell Factor 1-Expressing Memory-like CD8+ T Cells Sustain the Immune Response to Chronic Viral Infections
Published in Immunity (Cambridge, Mass.) (16-08-2016)“…Chronic infections promote the terminal differentiation (or “exhaustion”) of T cells and are thought to preclude the formation of memory T cells. In contrast,…”
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Optimizing Early Clinical Investigations in Cancer Immunotherapy: The Translational Journey of RG6292, a Novel, Selective Treg‐Depleting Antibody
Published in Clinical pharmacology and therapeutics (01-09-2024)“…The multifaceted IL‐2/IL‐2R biology and its modulation by promising therapeutic agents are highly relevant topics in the cancer immunotherapy field. A novel…”
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CD25 targeting with the afucosylated human IgG1 antibody RG6292 eliminates regulatory T cells and CD25+ blasts in acute myeloid leukemia
Published in Frontiers in oncology (02-05-2023)“…Acute Myeloid leukemia is a heterogeneous disease that requires novel targeted treatment options tailored to the patients' specific microenvironment and blast…”
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Differences in the transduction of canonical Wnt signals demarcate effector and memory CD8 T cells with distinct recall proliferation capacity
Published in The Journal of immunology (1950) (15-09-2014)“…Protection against reinfection is mediated by Ag-specific memory CD8 T cells, which display stem cell-like function. Because canonical Wnt (Wingless/Int1)…”
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CD25 Targeting Eliminates Regulatory T Cells and CD25+ Blasts in Acute Myeloid Leukemia
Published in Blood (15-11-2022)Get full text
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