Search Results - "Pourmousa, Mohsen"
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Structural properties of apolipoprotein A-I mimetic peptides that promote ABCA1-dependent cholesterol efflux
Published in Scientific reports (13-02-2018)“…Peptides mimicking the major protein of highdensity lipoprotein (HDL), apolipoprotein A-I (apoA-I), are promising therapeutics for cardiovascular diseases…”
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2
Novel Insights to the Design of Apolipoprotein AI Mimetic Peptides
Published in Biophysical journal (02-02-2018)Get full text
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3
Molecular dynamics simulations of lipid nanodiscs
Published in Biochimica et biophysica acta. Biomembranes (01-10-2018)“…A lipid nanodisc is a discoidal lipid bilayer stabilized by proteins, peptides, or polymers on its edge. Nanodiscs have two important connections to structural…”
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Early stages of interactions of cell-penetrating peptide penetratin with a DPPC bilayer
Published in Chemistry and physics of lipids (01-04-2013)“…•We model the cell penetrating peptide penetratin and its interactions with membrenes.•We show the importance of basic and aromatic residues of…”
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Tertiary structure of apolipoprotein A-I in nascent high-density lipoproteins
Published in Proceedings of the National Academy of Sciences - PNAS (15-05-2018)“…Understanding the function of high-density lipoprotein (HDL) requires detailed knowledge of the structure of its primary protein, apolipoprotein A-I (APOA1)…”
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Molecular Dynamic Studies of Transportan Interacting with a DPPC Lipid Bilayer
Published in The journal of physical chemistry. B (10-01-2013)“…Translocation of peptides through cellular membranes is a fundamental problem in developing antimicrobial peptides and in drug delivery. There is a class of…”
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Flipped C-Terminal Ends of APOA1 Promote ABCA1-Dependent Cholesterol Efflux by Small HDLs
Published in Circulation (New York, N.Y.) (05-03-2024)“…Cholesterol efflux capacity (CEC) predicts cardiovascular disease independently of high-density lipoprotein (HDL) cholesterol levels. Isolated small HDL…”
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Calcium Parameters in CHARMM Force Field Revisited
Published in Biophysical journal (16-02-2016)Get full text
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Cholesterol under oxidative stress—How lipid membranes sense oxidation as cholesterol is being replaced by oxysterols
Published in Free radical biology & medicine (01-07-2015)“…The behavior of oxysterols in phospholipid membranes and their effects on membrane properties were investigated by means of dynamic light scattering,…”
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Characterization of Apolipoprotein Mimetic Peptides on Nascent High Density Lipoproteins
Published in Biophysical journal (03-02-2017)Get full text
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Identification of a novel lipid binding motif in apolipoprotein B by the analysis of hydrophobic cluster domains
Published in Biochimica et biophysica acta. Biomembranes (01-02-2017)“…Apolipoprotein B (apoB) is a large amphipathic protein that is the structural scaffold for the formation of several classes of lipoproteins involved in lipid…”
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Dehydroergosterol as an Analogue for Cholesterol: Why It Mimics Cholesterol So Wellor Does It?
Published in The journal of physical chemistry. B (03-07-2014)“…Although dehydroergosterol (DHE) is one of the most commonly used cholesterol (CHOL) reporters, it has remained unclear why it performs well compared with most…”
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Oxidation of Cholesterol Changes the Physical Properties of Lipid Membranes
Published in Biophysical journal (16-02-2016)Get full text
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Molecular Dynamics Studies of Interactions of Phospholipid Membranes with Dehydroergosterol and Penetrating Peptides
Published 01-01-2011“…We have performed molecular modeling of membrane and peptide systems by employing the classical molecular dynamics method and force field parameterizations. In…”
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Dissertation