Search Results - "Pourgholami, Mohammad Hossein"
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In vivo C6 glioma models: an update and a guide toward a more effective preclinical evaluation of potential anti-glioblastoma drugs
Published in Reviews in the neurosciences (26-02-2024)“…Glioblastoma multiform (GBM) is the most common primary brain tumor with a poor prognosis and few therapeutic choices. tumor models are useful for enhancing…”
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Albendazole: a Potent Inhibitor of Vascular Endothelial Growth Factor and Malignant Ascites Formation in OVCAR-3 Tumor-Bearing Nude Mice
Published in Clinical cancer research (15-03-2006)“…Purpose: Angiogenesis and vessel hyperpermeability are the two factors leading to the formation of ascites. Vascular endothelial growth factor (VEGF) plays a…”
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The effects of anticancer medicinal herbs on vascular endothelial growth factor based on pharmacological aspects: a review study
Published in Nutrition and cancer (2021)“…As a complicated process of forming new blood vessels from the present vasculature endothelium, angiogenesis plays a critical role in the progression of…”
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Molecular Pharmacology and Novel Potential Therapeutic Applications of Fingolimod
Published in Frontiers in pharmacology (16-02-2022)“…Fingolimod is a well-tolerated, highly effective disease-modifying therapy successfully utilized in the management of multiple sclerosis. The active…”
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Eslicarbazepine induces apoptosis and cell cycle arrest in C6 glioma cells in vitro and suppresses tumor growth in an intracranial rat model
Published in BMC cancer (04-09-2024)“…Glioblastoma multiforme (GBM) is the most malignant brain tumor, with a poor prognosis and life expectancy of 14-16 months after diagnosis. The standard…”
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Synthetic miR-21 decoy circularized by tRNA splicing mechanism inhibited tumorigenesis in glioblastoma in vitro and in vivo models
Published in Molecular therapy. Nucleic acids (13-06-2023)“…Glioblastoma multiforme (GBM) is the deadliest primary central nervous system tumor. miRNAs (miRs), a class of non-coding RNAs, are considered pivotal…”
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CLEC19A overexpression inhibits tumor cell proliferation/migration and promotes apoptosis concomitant suppression of PI3K/AKT/NF-κB signaling pathway in glioblastoma multiforme
Published in BMC cancer (02-01-2024)“…GBM is the most frequent malignant primary brain tumor in humans. The CLEC19A is a member of the C-type lectin family, which has a high expression in brain…”
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Oestrogen receptors are prognostic factors in malignant peritoneal mesothelioma
Published in Journal of cancer research and clinical oncology (01-06-2013)“…Background Malignant peritoneal mesothelioma (MPM) is a rare and fatal cancer. Females are found to survive longer than males after treatment, suggesting a…”
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Inhibition of Cell Proliferation, Vascular Endothelial Growth Factor and Tumor Growth by Albendazole
Published in Cancer investigation (01-01-2009)“…Vascular endothelial growth factor (VEGF) is the key molecule mediating tumor growth and malignant ascites formation. We recently reported that, in an end…”
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Initial Report on Differential Expression of Sprouty Proteins 1 and 2 in Human Epithelial Ovarian Cancer Cell Lines
Published in Journal of Oncology (01-01-2012)“…Sprouty (Spry) proteins, modulators of receptor tyrosine kinase signaling pathways, have been shown to be deregulated in a variety of pathological conditions…”
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11
The role of VEGF in cancer-induced angiogenesis and research progress of drugs targeting VEGF
Published in European journal of pharmacology (15-06-2023)“…Angiogenesis is a double-edged sword; it is a mechanism that defines the boundary between health and disease. In spite of its central role in physiological…”
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12
CLEC19A overexpression inhibits tumor cell proliferation/migration and promotes apoptosis concomitant suppression of PI3K/AKT/NF-κB signaling pathway in glioblastoma multiforme
Published in BMC cancer (02-01-2024)“…Background GBM is the most frequent malignant primary brain tumor in humans. The CLEC19A is a member of the C-type lectin family, which has a high expression…”
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13
Intraperitoneal and intraamygdala N6-cyclohexyladenosine suppress hippocampal kindled seizures in rats
Published in Brain research (01-03-2000)“…Effects of intraperitoneal and intraamygdala N 6-cyclohexyladenosine (CHA), a selective adenosine A 1 receptor agonist, and 1,3-dimethyl-8-cyclopentylxanthine…”
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14
Minocycline inhibits malignant ascites of ovarian cancer through targeting multiple signaling pathways
Published in Gynecologic oncology (01-04-2013)“…Abstract Objectives To evaluate the effect of minocycline on the expression of cytokines and growth factors responsible for malignant ascite formation. Methods…”
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HAX1 Augments Cell Proliferation, Migration, Adhesion, and Invasion Induced by Urokinase-Type Plasminogen Activator Receptor
Published in Journal of Oncology (01-01-2012)“…The urokinase-type plasminogen activator receptor (uPAR) is a cell surface receptor which has a multifunctional task in the process of tumorigenesis including…”
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Utility of Vascular Endothelial Growth Factor Inhibitors in the Treatment of Ovarian Cancer: From Concept to Application
Published in Journal of Oncology (01-01-2012)“…Despite recent advances in the management of ovarian cancer, it remains the most lethal gynecologic malignancy. Vascular endothelial growth factor (VEGF) has…”
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Intraperitoneal and intraamygdala N(6)-cyclohexyladenosine suppress hippocampal kindled seizures in rats
Published in Brain research (06-03-2000)“…Effects of intraperitoneal and intraamygdala N(6)-cyclohexyladenosine (CHA), a selective adenosine A(1) receptor agonist, and…”
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