Search Results - "Pourgholami, Mohammad Hossein"

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  1. 1

    In vivo C6 glioma models: an update and a guide toward a more effective preclinical evaluation of potential anti-glioblastoma drugs by Pournajaf, Safura, Afsordeh, Nastaran, Pourgholami, Mohammad Hossein

    Published in Reviews in the neurosciences (26-02-2024)
    “…Glioblastoma multiform (GBM) is the most common primary brain tumor with a poor prognosis and few therapeutic choices. tumor models are useful for enhancing…”
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    Journal Article
  2. 2

    Albendazole: a Potent Inhibitor of Vascular Endothelial Growth Factor and Malignant Ascites Formation in OVCAR-3 Tumor-Bearing Nude Mice by Pourgholami, Mohammad Hossein, Yan Cai, Zhao, Lu, Ying, Wang, Lisa, Morris, David Lawson

    Published in Clinical cancer research (15-03-2006)
    “…Purpose: Angiogenesis and vessel hyperpermeability are the two factors leading to the formation of ascites. Vascular endothelial growth factor (VEGF) plays a…”
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    Journal Article
  3. 3

    The effects of anticancer medicinal herbs on vascular endothelial growth factor based on pharmacological aspects: a review study by Fakhri, Sajad, Abbaszadeh, Fatemeh, Jorjani, Masoumeh, Pourgholami, Mohammad Hossein

    Published in Nutrition and cancer (2021)
    “…As a complicated process of forming new blood vessels from the present vasculature endothelium, angiogenesis plays a critical role in the progression of…”
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  4. 4

    Molecular Pharmacology and Novel Potential Therapeutic Applications of Fingolimod by Pournajaf, Safura, Dargahi, Leila, Javan, Mohammad, Pourgholami, Mohammad Hossein

    Published in Frontiers in pharmacology (16-02-2022)
    “…Fingolimod is a well-tolerated, highly effective disease-modifying therapy successfully utilized in the management of multiple sclerosis. The active…”
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  5. 5

    Eslicarbazepine induces apoptosis and cell cycle arrest in C6 glioma cells in vitro and suppresses tumor growth in an intracranial rat model by Afsordeh, Nastaran, Pournajaf, Safura, Bayat, Hadi, Mohajerani, Fatemeh, Shojaei, Amir, Mirnajafi-Zadeh, Javad, Pourgholami, Mohammad Hossein

    Published in BMC cancer (04-09-2024)
    “…Glioblastoma multiforme (GBM) is the most malignant brain tumor, with a poor prognosis and life expectancy of 14-16 months after diagnosis. The standard…”
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    Journal Article
  6. 6

    Synthetic miR-21 decoy circularized by tRNA splicing mechanism inhibited tumorigenesis in glioblastoma in vitro and in vivo models by Bayat, Hadi, Pourgholami, Mohammad Hossein, Rahmani, Saeid, Pournajaf, Safura, Mowla, Seyed Javad

    Published in Molecular therapy. Nucleic acids (13-06-2023)
    “…Glioblastoma multiforme (GBM) is the deadliest primary central nervous system tumor. miRNAs (miRs), a class of non-coding RNAs, are considered pivotal…”
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  7. 7
  8. 8

    Oestrogen receptors are prognostic factors in malignant peritoneal mesothelioma by Pillai, Krishna, Pourgholami, Mohammad Hossein, Chua, Terence C., Morris, David Lawson

    “…Background Malignant peritoneal mesothelioma (MPM) is a rare and fatal cancer. Females are found to survive longer than males after treatment, suggesting a…”
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  9. 9

    Inhibition of Cell Proliferation, Vascular Endothelial Growth Factor and Tumor Growth by Albendazole by Pourgholami, Mohammad Hossein, Cai, Zhao Yan, Wang, Lisa, Badar, Samina, Links, Matthew, Morris, David Lawson

    Published in Cancer investigation (01-01-2009)
    “…Vascular endothelial growth factor (VEGF) is the key molecule mediating tumor growth and malignant ascites formation. We recently reported that, in an end…”
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  10. 10

    Initial Report on Differential Expression of Sprouty Proteins 1 and 2 in Human Epithelial Ovarian Cancer Cell Lines by Moghaddam, Samar Masoumi, Amini, Afshin, Wei, Ai-Qun, Pourgholami, Mohammad Hossein, Morris, David Lawson

    Published in Journal of Oncology (01-01-2012)
    “…Sprouty (Spry) proteins, modulators of receptor tyrosine kinase signaling pathways, have been shown to be deregulated in a variety of pathological conditions…”
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  11. 11

    The role of VEGF in cancer-induced angiogenesis and research progress of drugs targeting VEGF by Ghalehbandi, Seyedehdelaram, Yuzugulen, Jale, Pranjol, Md Zahidul Islam, Pourgholami, Mohammad Hossein

    Published in European journal of pharmacology (15-06-2023)
    “…Angiogenesis is a double-edged sword; it is a mechanism that defines the boundary between health and disease. In spite of its central role in physiological…”
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  12. 12
  13. 13

    Intraperitoneal and intraamygdala N6-cyclohexyladenosine suppress hippocampal kindled seizures in rats by Mirnajafi-Zadeh, Javad, Fathollahi, Yaghoub, Pourgholami, Mohammad Hossein

    Published in Brain research (01-03-2000)
    “…Effects of intraperitoneal and intraamygdala N 6-cyclohexyladenosine (CHA), a selective adenosine A 1 receptor agonist, and 1,3-dimethyl-8-cyclopentylxanthine…”
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    Journal Article
  14. 14

    Minocycline inhibits malignant ascites of ovarian cancer through targeting multiple signaling pathways by Pourgholami, Mohammad Hossein, Ataie-Kachoie, Parvin, Badar, Samina, Morris, David Lawson

    Published in Gynecologic oncology (01-04-2013)
    “…Abstract Objectives To evaluate the effect of minocycline on the expression of cytokines and growth factors responsible for malignant ascite formation. Methods…”
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  15. 15

    HAX1 Augments Cell Proliferation, Migration, Adhesion, and Invasion Induced by Urokinase-Type Plasminogen Activator Receptor by Mekkawy, Ahmed H., Morris, David Lawson, Pourgholami, Mohammad Hossein

    Published in Journal of Oncology (01-01-2012)
    “…The urokinase-type plasminogen activator receptor (uPAR) is a cell surface receptor which has a multifunctional task in the process of tumorigenesis including…”
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  16. 16

    Utility of Vascular Endothelial Growth Factor Inhibitors in the Treatment of Ovarian Cancer: From Concept to Application by Amini, Afshin, Masoumi Moghaddam, Samar, Morris, David Lawson, Pourgholami, Mohammad Hossein

    Published in Journal of Oncology (01-01-2012)
    “…Despite recent advances in the management of ovarian cancer, it remains the most lethal gynecologic malignancy. Vascular endothelial growth factor (VEGF) has…”
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  17. 17

    Intraperitoneal and intraamygdala N(6)-cyclohexyladenosine suppress hippocampal kindled seizures in rats by Mirnajafi-Zadeh, J, Fathollahi, Y, Pourgholami, M H

    Published in Brain research (06-03-2000)
    “…Effects of intraperitoneal and intraamygdala N(6)-cyclohexyladenosine (CHA), a selective adenosine A(1) receptor agonist, and…”
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    Journal Article