Search Results - "Poupon, Marie France"

Ultrahigh dose-rate FLASH irradiation increases the differential response between normal and tumor tissue in mice by Favaudon, Vincent, Caplier, Laura, Monceau, Virginie, Pouzoulet, Frédéric, Sayarath, Mano, Fouillade, Charles, Poupon, Marie-France, Brito, Isabel, Hupé, Philippe, Bourhis, Jean, Hall, Janet, Fontaine, Jean-Jacques, Vozenin, Marie-Catherine

“…In vitro studies suggested that sub-millisecond pulses of radiation elicit less genomic instability than continuous, protracted irradiation at the same total…”
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Molecular profiling of patient-derived breast cancer xenografts by Reyal, Fabien, Guyader, Charlotte, Decraene, Charles, Lucchesi, Carlo, Auger, Nathalie, Assayag, Franck, De Plater, Ludmilla, Gentien, David, Poupon, Marie-France, Cottu, Paul, De Cremoux, Patricia, Gestraud, Pierre, Vincent-Salomon, Anne, Fontaine, Jean-Jacques, Roman-Roman, Sergio, Delattre, Olivier, Decaudin, Didier, Marangoni, Elisabetta

“…Identification of new therapeutic agents for breast cancer (BC) requires preclinical models that reproduce the molecular characteristics of their respective…”
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Intracellular STING inactivation sensitizes breast cancer cells to genotoxic agents by Gaston, Julie, Cheradame, Laura, Yvonnet, Vanessa, Deas, Olivier, Poupon, Marie-France, Judde, Jean-Gabriel, Cairo, Stefano, Goffin, Vincent

“…Activation of the IFN/STAT1 pathway is closely associated with drug response and recurrence of breast cancer treated by chemotherapy. The aim of the current…”
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A New Model of Patient Tumor-Derived Breast Cancer Xenografts for Preclinical Assays by MARANGONI, Elisabetta, VINCENT -SALOMON, Anne, REBUCCI, Magali, TRAN -PERENNOU, Carine, SASTRE-GARAU, Xavier, SIGAL-ZAFRANI, Brigitte, DELATTRE, Olivier, DIBRAS, Véronique, POUPON, Marie-France, AUGER, Nathalie, DEGEORGES, Armelle, ASSAYAG, Franck, DE CREMOUX, Patricia, DE PLATER, Ludmilla, GUYADER, Charlotte, DE PINIEUX, Gonzague, JUDDE, Jean-Gabriel

“…Purpose: To establish a panel of human breast cancer (HBC) xenografts in immunodeficient mice suitable for pharmacologic preclinical assays. Experimental…”
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A “class action” against the microenvironment: do cancer cells cooperate in metastasis? by Bidard, François-Clément, Pierga, Jean-Yves, Vincent-Salomon, Anne, Poupon, Marie-France

“…The authors review how cancer cells may cooperate in metastasis by means of microenvironmental changes. The main mechanisms underlying this cooperation are…”
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Netrin-4 inhibits angiogenesis via binding to neogenin and recruitment of Unc5B by Lejmi, Esma, Leconte, Laurence, Pédron-Mazoyer, Sandrine, Ropert, Stanislas, Raoul, William, Lavalette, Sophie, Bouras, Ilyes, Feron, Jean-Guillaume, Maitre-Boube, Martine, Assayag, Franck, Feumi, Charles, Alemany, Monica, Jie, Tan Xian, Merkulova, Tatyana, Poupon, Marie-France, Ruchoux, Marie-Magdeleine, Tobelem, Gérard, Sennlaub, Florian, Plouët, Jean

“…Netrins are secreted molecules with roles in axon guidance and angiogenesis. We identified Netrin-4 as a gene specifically overexpressed in VEGF-stimulated…”
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Establishment of human colon cancer cell lines from fresh tumors versus xenografts : Comparison of success rate and cell line features by DANGLES-MARIE, Virginie, POCARD, Marc, DUTRILLAUX, Bernard, PRAZ, Francoise, BELLET, Dominique, POUPON, Marie-France, RICHON, Sophie, WEISWALD, Louis-Bastien, ASSAYAG, Franck, SAULNIER, Patrick, JUDDE, Jean-Gabriel, JANNEAU, Jean-Louis, AUGER, Nathalie, VALIDIRE, Pierre

“…Obtaining representative human colon cancer cell lines from fresh tumors is technically difficult. Using 32 tumor fragments from patients with colon cancer,…”
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Diabetes protects from prostate cancer by downregulating androgen receptor: new insights from LNCaP cells and PAC120 mouse model by Barbosa-Desongles, Anna, Hernández, Cristina, De Torres, Ines, Munell, Francina, Poupon, Marie-France, Simó, Rafael, Selva, David M

“…Type 2 diabetes has been associated with decreased risk of prostate cancer in observational studies, and this inverse association has been recently confirmed…”
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Molecular Mechanisms Underlying Effects of Epidermal Growth Factor Receptor Inhibition on Invasion, Proliferation, and Angiogenesis in Experimental Glioma by GUILLAMO, Jean-Sébastien, DE BOÜARD, Sophie, VALABLE, Samuel, MARTEAU, Lena, LEURAUD, Pascal, MARIE, Yannick, POUPON, Marie-France, PARIENTI, Jean-Jacques, RAYMOND, Eric, PESCHANSKI, Marc

“…Purpose: Epidermal growth factor receptor (EGFR) signal transduction pathways are implicated in malignant glioma aggressiveness and promote tumor cell…”
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Multicenter Randomized Phase II Study of Two Schedules of Docetaxel, Estramustine, and Prednisone Versus Mitoxantrone Plus Prednisone in Patients With Metastatic Hormone-Refractory Prostate Cancer by OUDARD, Stéphane, BANU, Eugeniu, GUINET, Francois, POUPON, Marie-France, ANDRIEU, Jean-Marie, BEUZEBOC, Philippe, VOOG, Eric, DOURTHE, Louis Marie, HARDY-BESSARD, Anne Claire, LINASSIER, Claude, SCOTTE, Florian, BANU, Adela, COSCAS, Yvan

“…Mitoxantrone-corticosteroid is currently the standard palliative treatment in hormone-refractory prostate cancer (HRPC) patients. Recent clinical trials…”
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Human colorectal tumors and metastases express Gb3 and can be targeted by an intestinal pathogen-based delivery tool by Falguières, Thomas, Maak, Matthias, von Weyhern, Claus, Sarr, Marianne, Sastre, Xavier, Poupon, Marie-France, Robine, Sylvie, Johannes, Ludger, Janssen, Klaus-Peter

“…The targeting of solid tumors requires delivery tools that resist intracellular and extracellular inactivation, and that are taken up specifically by tumor…”
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Geraniol, a component of plant essential oils, modulates DNA synthesis and potentiates 5-fluorouracil efficacy on human colon tumor xenografts by Carnesecchi, Stephanie, Bras-Gonçalves, Rui, Bradaia, Amyaouch, Zeisel, Mirjam, Gossé, Francine, Poupon, Marie-France, Raul, Francis

“…We investigated on colon cancer cells the effect of geraniol on thymidylate synthase and thymidine kinase expression, two enzymes related to 5-fluorouracil…”
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p53 dependent cell‐cycle arrest triggered by chemotherapy in xenografted breast tumors by Varna, Mariana, Lehmann‐Che, Jacqueline, Turpin, Elisabeth, Marangoni, Elizabetha, El‐Bouchtaoui, Morad, Jeanne, Marion, Grigoriu, Carmen, Ratajczak, Philippe, Leboeuf, Christophe, Plassa, Louis‐François, Ferreira, Irmine, Poupon, Marie‐France, Janin, Anne, de Thé, Hugues, Bertheau, Philippe

“…The major long‐term prognostic factor for breast cancer patients treated by first‐line chemotherapy is response to treatment. We have previously shown that…”
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Src kinase contributes to the metastatic spread of carcinoma cells by BOYER, Brigitte, BOURGEOIS, Yveline, POUPON, Marie-France

“…The involvement of Src kinase during carcinoma metastasis has been explored by using the NBT-II rat carcinoma cell line, which can be induced to scatter in…”
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Risk of hormone escape in a human prostate cancer model depends on therapy modalities and can be reduced by tyrosine kinase inhibitors by Guyader, Charlotte, Céraline, Jocelyn, Gravier, Eléonore, Morin, Aurélie, Michel, Sandrine, Erdmann, Eva, de Pinieux, Gonzague, Cabon, Florence, Bergerat, Jean-Pierre, Poupon, Marie-France, Oudard, Stéphane

“…Almost all prostate cancers respond to androgen deprivation treatment but many recur. We postulated that risk of hormone escape--frequency and delay--are…”
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Grb2‐SH3 ligand inhibits the growth of HER2+ cancer cells and has antitumor effects in human cancer xenografts alone and in combination with docetaxel by Gril, Brunilde, Vidal, Michel, Assayag, Franck, Poupon, Marie‐France, Liu, Wang‐Qing, Garbay, Christiane

“…HER2 represents an important signaling pathway in breast and other cancers. Herceptin has demonstrated clinical activity, but resistance is common. Thus, new…”
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Molecular Structure of Double-Minute Chromosomes Bearing Amplified Copies of the Epidermal Growth Factor Receptor Gene in Gliomas by Vogt, Nicolas, Lefèvre, Sandrine-Hélène, Apiou, Françoise, Dutrillaux, Anne-Marie, Cör, Andrej, Leuraud, Pascal, Poupon, Marie-France, Dutrillaux, Bernard, Debatisse, Michelle, Malfoy, Bernard, Alt, Frederick W.

“…Amplification of the epidermal growth factor receptor gene on double minutes is recurrently observed in cells of advanced gliomas, but the structure of these…”
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Lonidamine triggers apoptosis via a direct, Bcl-2-inhibited effect on the mitochondrial permeability transition pore by RAVAGNAN, L, MARZO, I, ZHIHUA XIE, REED, J. C, KROEMER, G, COSTANTINI, P, SUSIN, S. A, ZAMZAMI, N, PETIT, P. X, HIRSCH, F, GOULBERN, M, POUPON, M.-F, MICCOLI, L

“…The molecular mode of action of lonidamine, a therapeutic agent employed in cancer chemotherapy, has been elusive. Here we provide evidence that lonidamine…”
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Strong inhibition of Ewing tumor xenograft growth by combination of human interferon-alpha or interferon-beta with ifosfamide by SANCEAU, Josiane, POUPON, Marie-France, DELATTRE, Olivier, SASTRE-GARAU, Xavier, WIETZERBIN, Juana

“…Ewing sarcoma is the second most common bone tumor in childhood. Despite aggressive chemotherapy and radiotherapy strategies, the prognosis of patients with…”
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ADP ribosylation factor like 2 (Arl2) regulates breast tumor aggressivity in immunodeficient mice by Beghin, Anne, Belin, Stéphane, Hage-Sleiman, Rouba, Hage Sleiman, Rouba, Brunet Manquat, Stéphanie, Goddard, Sophie, Tabone, Eric, Jordheim, Lars P, Treilleux, Isabelle, Poupon, Marie-France, Diaz, Jean-Jacques, Dumontet, Charles

“…We have previously reported that ADP ribosylation factor like 2 (Arl2), a small GTPase, content influences microtubule dynamics and cell cycle distribution in…”
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