Search Results - "Poupon, Gwenola"

Missense mutation of Fmr1 results in impaired AMPAR-mediated plasticity and socio-cognitive deficits in mice by Prieto, Marta, Folci, Alessandra, Poupon, Gwénola, Schiavi, Sara, Buzzelli, Valeria, Pronot, Marie, François, Urielle, Pousinha, Paula, Lattuada, Norma, Abelanet, Sophie, Castagnola, Sara, Chafai, Magda, Khayachi, Anouar, Gwizdek, Carole, Brau, Frédéric, Deval, Emmanuel, Francolini, Maura, Bardoni, Barbara, Humeau, Yann, Trezza, Viviana, Martin, Stéphane

“…Fragile X syndrome (FXS) is the most frequent form of inherited intellectual disability and the best-described monogenic cause of autism. CGG-repeat expansion…”
Get full text

Cutting Edge: Lectin-Like Transcript 1 Is a Ligand for the CD161 Receptor by Aldemir, Hatice, Prod'homme, Virginie, Dumaurier, Marie-Jeanne, Retiere, Christelle, Poupon, Gwenola, Cazareth, Julie, Bihl, Franck, Braud, Veronique M

“…Human NK cells and subsets of T cells or NKT cells express the orphan C-type lectin receptor CD161 (NKR-P1A) of unknown function. In contrast to rodents that…”
Get full text

Characterization of Alternatively Spliced Transcript Variants of CLEC2D Gene by Germain, Claire, Bihl, Franck, Zahn, Stefan, Poupon, Gwenola, Dumaurier, Marie-Jeanne, Rampanarivo, Hariniaina Henintsoa, Padkjær, Søren Berg, Spee, Pieter, Braud, Veronique M.

“…Lectin-like transcript 1 (LLT1) encoded by CLEC2D gene is a C-type lectin-like molecule interacting with human CD161 (NKR-P1A) receptor expressed by natural…”
Get full text

Identification of an acute functional cross-talk between amyloid-β and glucocorticoid receptors at hippocampal excitatory synapses by Kootar, Scherazad, Frandemiche, Marie-Lise, Dhib, Gihen, Mouska, Xavier, Lorivel, Thomas, Poupon-Silvestre, Gwenola, Hunt, Hazel, Tronche, François, Bethus, Ingrid, Barik, Jacques, Marie, Hélène

“…Amyloid-β is a peptide released by synapses in physiological conditions and its pathological accumulation in brain structures necessary for memory processing…”
Get full text

Sumoylation regulates FMRP-mediated dendritic spine elimination and maturation by Khayachi, Anouar, Gwizdek, Carole, Poupon, Gwénola, Alcor, Damien, Chafai, Magda, Cassé, Frédéric, Maurin, Thomas, Prieto, Marta, Folci, Alessandra, De Graeve, Fabienne, Castagnola, Sara, Gautier, Romain, Schorova, Lenka, Loriol, Céline, Pronot, Marie, Besse, Florence, Brau, Frédéric, Deval, Emmanuel, Bardoni, Barbara, Martin, Stéphane

“…Fragile X syndrome (FXS) is the most frequent inherited cause of intellectual disability and the best-studied monogenic cause of autism. FXS results from the…”
Get full text

Bidirectional regulation of synaptic SUMOylation by Group 1 metabotropic glutamate receptors by Pronot, Marie, Poupon, Gwénola, Pizzamiglio, Lara, Prieto, Marta, Chato-Astrain, Isabel, Lacagne, Iliona, Schorova, Lenka, Folci, Alessandra, Brau, Frédéric, Martin, Stéphane

“…SUMOylation is a post-translational modification essential to cell homeostasis. A tightly controlled equilibrium between SUMOylation and deSUMOylation…”
Get full text

The synaptic balance between sumoylation and desumoylation is maintained by the activation of metabotropic mGlu5 receptors by Schorova, Lenka, Pronot, Marie, Poupon, Gwénola, Prieto, Marta, Folci, Alessandra, Khayachi, Anouar, Brau, Frédéric, Cassé, Frédéric, Gwizdek, Carole, Martin, Stéphane

“…Sumoylation is a reversible post-translational modification essential to the modulation of neuronal function, including neurotransmitter release and synaptic…”
Get full text

Involvement of Phosphodiesterase 2A Activity in the Pathophysiology of Fragile X Syndrome by Maurin, Thomas, Melancia, Francesca, Jarjat, Marielle, Castro, Liliana, Costa, Lara, Delhaye, Sébastien, Khayachi, Anouar, Castagnola, Sara, Mota, Elia, Di Giorgio, Audrey, Servadio, Michela, Drozd, Malgorzata, Poupon, Gwénola, Schiavi, Sara, Sardone, Lara, Azoulay, Stéphane, Ciranna, Lucia, Martin, Stéphane, Vincent, Pierre, Trezza, Viviana, Bardoni, Barbara

“…The fragile X mental retardation protein (FMRP) is an RNA-binding protein involved in translational regulation of mRNAs that play key roles in synaptic…”
Get full text

Physiological and pathophysiological control of synaptic GluN2B-NMDA receptors by the C-terminal domain of amyloid precursor protein by Pousinha, Paula A, Mouska, Xavier, Raymond, Elisabeth F, Gwizdek, Carole, Dhib, Gihen, Poupon, Gwenola, Zaragosi, Laure-Emmanuelle, Giudici, Camilla, Bethus, Ingrid, Pacary, Emilie, Willem, Michael, Marie, Hélène

“…The amyloid precursor protein (APP) harbors physiological roles at synapses and is central to Alzheimer's disease (AD) pathogenesis. Evidence suggests that APP…”
Get full text

Activity-dependent regulation of the sumoylation machinery in rat hippocampal neurons by Loriol, Céline, Khayachi, Anouar, Poupon, Gwénola, Gwizdek, Carole, Martin, Stéphane

“…Background information Sumoylation is a key post‐translational modification by which the Small Ubiquitin‐like MOdifier (SUMO) polypeptide is covalently…”
Get full text

Developmental regulation and spatiotemporal redistribution of the sumoylation machinery in the rat central nervous system by Loriol, Céline, Parisot, Joséphine, Poupon, Gwénola, Gwizdek, Carole, Martin, Stéphane

“…Small Ubiquitin-like MOdifier protein (SUMO) is a key regulator of nuclear functions but little is known regarding the role of the post-translational…”
Get full text

Proteomic Identification of an Endogenous Synaptic SUMOylome in the Developing Rat Brain by Pronot, Marie, Kieffer, Félicie, Gay, Anne-Sophie, Debayle, Delphine, quet, Raphaël, Poupon, Gwénola, Schorova, Lenka, Martin, Stéphane, Gwizdek, Carole

“…Synapses are highly specialized structures that interconnect neurons to form functional networks dedicated to neuronal communication. During brain development,…”
Get full text

Combining affinity purification and mass spectrometry to define the network of the nuclear proteins interacting with the N-terminal region of FMRP by Kieffer, Félicie, Hilal, Fahd, Gay, Anne-Sophie, Debayle, Delphine, Pronot, Marie, Poupon, Gwénola, Lacagne, Iliona, Bardoni, Barbara, Martin, Stéphane, Gwizdek, Carole

“…Fragile X-Syndrome (FXS) represents the most common inherited form of intellectual disability and the leading monogenic cause of Autism Spectrum Disorders. In…”
Get full text

mGlu5 receptors regulate synaptic sumoylation via a transient PKC-dependent diffusional trapping of Ubc9 into spines by Loriol, Céline, Cassé, Frédéric, Khayachi, Anouar, Poupon, Gwénola, Chafai, Magda, Deval, Emmanuel, Gwizdek, Carole, Martin, Stéphane

“…Sumoylation plays important roles in the modulation of protein function, neurotransmission and plasticity, but the mechanisms regulating this…”
Get full text

Lectin-like transcript 1 is a marker of germinal center-derived B-cell non-Hodgkin's lymphomas dampening natural killer cell functions by Germain, Claire, Guillaudeux, Thierry, Galsgaard, Elisabeth D, Hervouet, Catherine, Tekaya, Nedra, Gallouet, Anne-Sophie, Fassy, Julien, Bihl, Franck, Poupon, Gwenola, Lazzari, Anne, Spee, Pieter, Anjuère, Fabienne, Pangault, Céline, Tarte, Karin, Tas, Patrick, Xerri, Luc, Braud, Veronique M

“…Non-Hodgkin's lymphomas (NHLs) are malignant neoplasms which are clinically and biologically diverse. Their incidence is constantly increasing and despite…”
Get full text

Induction of Lectin-like Transcript 1 (LLT1) Protein Cell Surface Expression by Pathogens and Interferon-γ Contributes to Modulate Immune Responses by Germain, Claire, Meier, Anders, Jensen, Teis, Knapnougel, Perrine, Poupon, Gwenola, Lazzari, Anne, Neisig, Anne, Håkansson, Katarina, Dong, Tao, Wagtmann, Nicolai, Galsgaard, Elizabeth D., Spee, Pieter, Braud, Veronique M.

“…CD161 is a C-type lectin-like receptor expressed on human natural killer (NK) cells and subsets of T cells. CD161 has been described as an inhibitory receptor…”
Get full text

Primed antigen-specific CD4+ T cells are required for NK cell activation in vivo upon Leishmania major infection by Bihl, Franck, Pecheur, Julien, Bréart, Béatrice, Poupon, Gwenola, Cazareth, Julie, Julia, Valérie, Glaichenhaus, Nicolas, Braud, Véronique M

“…The ability of NK cells to rapidly produce IFN-gamma is an important innate mechanism of resistance to many pathogens including Leishmania major. Molecular and…”
Get full text

Cutting edge: lectin-like transcript 1 is a ligand for the CD161 receptor by Aldemir, Hatice, Prod'Homme, Virginie, Dumaurier, Marie-Jeanne, Retiere, Christelle, Poupon, Gwenola, Cazareth, Julie, Bihl, Franck, Braud, Veronique M

“…Human NK cells and subsets of T cells or NKT cells express the orphan C-type lectin receptor CD161 (NKR-P1A) of unknown function. In contrast to rodents that…”
Get full text

Proteomic Identification of an Endogenous Synaptic SUMOylome in the Developing Rat Brain by Pronot, Marie, Kieffer, Félicie, Gay, Anne-Sophie, Debayle, Delphine, Forquet, Raphaël, Poupon, Gwénola, Schorova, Lenka, Martin, Stéphane, Gwizdek, Carole

“…Synapses are highly specialized structures that interconnect neurons to form functional networks dedicated to neuronal communication. During brain development,…”
Get full text

Lectin-Like Transcript 1 Is a Ligand for the CD161 Receptor by Aldemir, Hatice, Prod'homme, Virginie, Dumaurier, Marie-Jeanne, Retiere, Christelle, Poupon, Gwenola, Cazareth, Julie, Bihl, Franck, Braud, Veronique M

“…Human NK cells and subsets of T cells or NKT cells express the orphan C-type lectin receptor CD161 (NKR-P1A) of unknown function. In contrast to rodents that…”
Get full text