Search Results - "Pounds, Rachel"

Vulval cancer in pregnancy: Two case reports by Gaunt, Ellen, Pounds, Rachel, Yap, Jason

“…Vulval cancer is rare in women of reproductive age. We report two cases of vulval squamous cell carcinoma (VSCC) in pregnancy. They presented with a solitary…”
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Aberrant activation of the Hedgehog signalling pathway in squamous cell carcinoma of the vulva as a potential target for cancer therapy by Yap, Jason K. W., Uddin, Khalil, Pounds, Rachel, O’Neill, Danielle, Kehoe, Sean, Ganesan, Raji, Dawson, Christopher W.

“…In a previous study, we showed that the Hedgehog (Hh) signalling pathway is aberrantly activated in vulval squamous cell carcinoma (VSCC). In this study, we…”
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Under expression of the Sonic Hedgehog receptor, Patched1 (PTCH1), is associated with an increased risk of local recurrence in squamous cell carcinoma of the vulva arising on a background of Lichen Sclerosus by Yap, Jason, Fox, Richard, Narsia, Natalie, Pinheiro-Maia, Sonia, Pounds, Rachel, Woodman, Ciaran, Luesley, David, Ganesan, Raji, Kehoe, Sean, Dawson, Christopher

“…Dysregulation of the Hedgehog (Hh) pathway has been described in a variety of cancers, including cervical cancer, a disease which shares a common aetiology…”
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The diagnostic conundrum of chronic ectopic pregnancy: A case report by O'Neill, Danielle, Pounds, Rachel, Vella, Josefa, Singh, Kavita, Yap, Jason

“…Chronic ectopic pregnancy (CEP) is a rare condition caused by implantation of trophoblastic tissue in the fallopian tube, which causes protracted tissue…”
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A graphic elicitation technique to represent patient rights by McGowan, Catherine R, Hellman, Nora, Baxter, Louisa, Chakma, Sonali, Nahar, Samchun, Daula, Ahasan Ud, Rowe, Kelly, Gilday, Josie, Kingori, Patricia, Pounds, Rachel, Cummings, Rachael

“…A patient charter is an explicit declaration of the rights of patients within a particular health care setting. In early 2020 the Save the Children Emergency…”
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En bloc resection of the external iliac vein along with broad ligament leiomyosarcoma: A case report by Ahmed, Fatima, Pounds, Rachel, Teo, Hong-Giap, Nevin, James, Singh, Kavita, Yap, Jason

“…Outcomes following the excision of the external iliac vein during gynaecological oncology surgery are poorly documented. This is because most gynaecological…”
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Fetal Limb Ischaemia in Twin-to-Twin Transfusion Syndrome by Kilby, Mark, Pounds, Rachel, Mannix, Paul

“…Objective. To describe the rare association between prenatal vascular limb occlusion and twin-to-twin transfusion syndrome. The Case. A woman with severe…”
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Repurposing itraconazole for the treatment of cancer by Pounds, Rachel, Leonard, Sarah, Dawson, Christopher, Kehoe, Sean

“…The repurposing of drugs is becoming increasingly attractive as it avoids the lengthy process and cost implications associated with bringing a novel drug to…”
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Prolonged interruption of chemotherapy in patients undergoing delayed debulking surgery for advanced high grade serous ovarian cancer is associated with a worse prognosis by Searle, Gemma, Pounds, Rachel, Phillips, Andrew, Kehoe, Sean, Balega, Janos, Singh, Kavita, Yap, Jason

“…The current standard of care for advanced high grade serous ovarian cancer (HGSC) comprises a combination of debulking surgery and platinum-based chemotherapy…”
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When Is It Safe to Omit Surgery in Primary Peritoneal Cancer With Small Volume Disease? by Pounds, Rachel, Kehoe, Sean

“…Primary peritoneal cancer (PPC) is considered a very rare condition, with mesotheliomas deemed the only true PPC when considering the cellular content and…”
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The role of preoperative computerized tomography (CT) scan of the pelvis and groin in the management of clinically early staged vulva squamous cell carcinoma by Pounds, Rachel, O'Neill, Danielle, Subba, Kamana, Garg, Akanksha, Scerif, Miski, Leong, Elizabeth, Nevin, James, Kehoe, Sean, Yap, Jason

“…Vulvar squamous cell carcinoma (VSCC) commonly metastasises through groin lymphatics. However, the use of pre-operative imaging in detecting inguinal nodal…”
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Evaluating the impact of the COVID-19 pandemic on tertiary gynaecological cancer care delivery: a population based study by Lowe-Zinola, Jack, Williamson, Megan, Gaunt, Ellen, Boulter, Holly, Pounds, Rachel, Kehoe, Sean, Yap, Jason

“…During the COVID-19 pandemic, reports of delays and alterations in cancer treatment pathways have emerged. We aim to evaluate the proportional impact of the…”
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Ulipristal acetate for uterine fibroids: 2 years of real world experience in a UK hospital by Woodhead, Natalie, Pounds, Rachel, Irani, Shirin, Pradhan, Poonam

“…Ulipristal acetate (UPA), is a selective progesterone-receptor modulator, it decreases fibroid size and reduces menstrual bleeding. We reviewed its use at the…”
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The impact on obstetric outcomes following complete amputation of the cervix uteri in fertility preservation surgery for cervical neoplasm by O’Neill, Danielle, Pounds, Rachel, Scully, Niall, Marriott, Natalie, Balega, Janos, Ganesan, Raji, Singh, Kavita, Yap, Jason

“…•Trachelectomy is a safe treatment for cervical cancer in women who desire fertility.•Isthmic glands are a reliable surrogate measurement of complete cervical…”
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Diaphragm disease in advanced ovarian cancer: Predictability of pre-operative imaging and safety of surgical intervention by Pounds, Rachel, Phillips, Andrew, Kehoe, Sean, Nevin, James, Sundar, Sudha, Elattar, Ahmed, Teo, Hong Giap, Singh, Kavita, Balega, Janos

“…To establish the positive predictive values of pre-operative identification with CT imaging of metastatic diaphragm disease in surgically managed cases of…”
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'Spigelian-type' hernia: a rare laparoscopic trocar site hernia following total laparoscopic hysterectomy by Leong, Elizabeth, Lloyd, Amelia, Pounds, Rachel, O'Neill, Danielle, Singh, Kavita, Yap, Jason

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Socioeconomic differences impact overall survival in advanced ovarian cancer (AOC) prior to achievement of standard therapy by Phillips, Andrew, Kehoe, Sean, Singh, Kavita, Elattar, Ahmed, Nevin, James, Balega, Janos, Pounds, Rachel, Elmodir, Ahmed, Pascoe, Jennifer, Fernando, Indrajit, Sundar, Sudha

“…Purpose Survival difference between socioeconomic groups with ovarian cancer has persisted in the United Kingdom despite efforts to reduce disparities in care…”
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A survey on the use of topical steroids in patients treated for lichen sclerosus-associated vulval squamous cell carcinoma by Pounds, Rachel, Tahir, Sanna, Dawson, Christopher, Woodman, Ciaran, Luesley, David, Yap, Jason

“…Evidence suggests that lichen sclerosus (LS) is the primary aetiological factor for local vulval recurrence (LVR) in vulval squamous cell carcinoma (VSCC). The…”
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Predictive value of the age-adjusted Charlston co-morbidity index on peri-operative complications, adjuvant chemotherapy usage and survival in patients undergoing debulking surgery after neo-adjuvant chemotherapy for advanced epithelial ovarian cancer by Phillips, Andrew, Singh, Kavita, Pounds, Rachel, Sundar, Sudha, Kehoe, Sean, Nevin, James, Elattar, Ahmed, Balega, Janos

“…The aim of this study was to determine whether the age-adjusted Charlston co-morbidity index (ACCI) can predict post-operative complications, adjuvant…”
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The diagnostic conundrum of chronic ectopic pregnancy: A case report by O'Neill, Danielle, Pounds, Rachel, Vella, Josefa, Singh, Kavita, Yap, Jason

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