Search Results - "Poultney, Christopher S."

Identification of Small Exonic CNV from Whole-Exome Sequence Data and Application to Autism Spectrum Disorder by Poultney, Christopher S., Goldberg, Arthur P., Drapeau, Elodie, Kou, Yan, Harony-Nicolas, Hala, Kajiwara, Yuji, De Rubeis, Silvia, Durand, Simon, Stevens, Christine, Rehnström, Karola, Palotie, Aarno, Daly, Mark J., Ma’ayan, Avi, Fromer, Menachem, Buxbaum, Joseph D.

“…Copy number variation (CNV) is an important determinant of human diversity and plays important roles in susceptibility to disease. Most studies of CNV carried…”
Get full text

A genome-wide RNA interference screen identifies new regulators of androgen receptor function in prostate cancer cells by Imberg-Kazdan, Keren, Ha, Susan, Greenfield, Alex, Poultney, Christopher S, Bonneau, Richard, Logan, Susan K, Garabedian, Michael J

“…The androgen receptor (AR) is a mediator of both androgen-dependent and castration-resistant prostate cancers. Identification of cellular factors affecting AR…”
Get full text

Rational design of temperature-sensitive alleles using computational structure prediction by Poultney, Christopher S, Butterfoss, Glenn L, Gutwein, Michelle R, Drew, Kevin, Gresham, David, Gunsalus, Kristin C, Shasha, Dennis E, Bonneau, Richard

“…Temperature-sensitive (ts) mutations are mutations that exhibit a mutant phenotype at high or low temperatures and a wild-type phenotype at normal temperature…”
Get full text

Insights into Autism Spectrum Disorder Genomic Architecture and Biology from 71 Risk Loci by Sanders, Stephan J., He, Xin, Willsey, A. Jeremy, Ercan-Sencicek, A. Gulhan, Samocha, Kaitlin E., Cicek, A. Ercument, Murtha, Michael T., Bal, Vanessa H., Bishop, Somer L., Dong, Shan, Goldberg, Arthur P., Jinlu, Cai, Keaney, John F., Klei, Lambertus, Mandell, Jeffrey D., Moreno-De-Luca, Daniel, Poultney, Christopher S., Robinson, Elise B., Smith, Louw, Solli-Nowlan, Tor, Su, Mack Y., Teran, Nicole A., Walker, Michael F., Werling, Donna M., Beaudet, Arthur L., Cantor, Rita M., Fombonne, Eric, Geschwind, Daniel H., Grice, Dorothy E., Lord, Catherine, Lowe, Jennifer K., Mane, Shrikant M., Martin, Donna M., Morrow, Eric M., Talkowski, Michael E., Sutcliffe, James S., Walsh, Christopher A., Yu, Timothy W., Ledbetter, David H., Martin, Christa Lese, Cook, Edwin H., Buxbaum, Joseph D., Daly, Mark J., Devlin, Bernie, Roeder, Kathryn, State, Matthew W.

“…Analysis of de novo CNVs (dnCNVs) from the full Simons Simplex Collection (SSC) (N = 2,591 families) replicates prior findings of strong association with…”
Get full text

One third of dynamic protein expression profiles can be predicted by a simple rate equation by Tchourine, Konstantine, Poultney, Christopher S, Wang, Li, Silva, Gustavo M, Manohar, Sandhya, Mueller, Christian L, Bonneau, Richard, Vogel, Christine

“…Cells respond to environmental stimuli with expression changes at both the mRNA and protein level, and a plethora of known and unknown regulators affect…”
Get more information

Integrated Inference and Analysis of Regulatory Networks from Multi-Level Measurements by Poultney, Christopher S., Greenfield, Alex, Bonneau, Richard

“…Regulatory and signaling networks coordinate the enormously complex interactions and processes that control cellular processes (such as metabolism and cell…”
Get full text

Sungear: interactive visualization and functional analysis of genomic datasets by Poultney, Christopher S., Gutiérrez, Rodrigo A., Katari, Manpreet S., Gifford, Miriam L., Paley, W. Bradford, Coruzzi, Gloria M., Shasha, Dennis E.

“…Sungear is a software system that supports a rapid, visually interactive and biologist-driven comparison of large datasets. The datasets can come from…”
Get full text

Wisdom of crowds for robust gene network inference by Marbach, Daniel, Costello, James C, Küffner, Robert, Vega, Nicole M, Prill, Robert J, Camacho, Diogo M, Allison, Kyle R, Kellis, Manolis, Collins, James J, Stolovitzky, Gustavo

“…This analysis comprehensively compares methods for gene regulatory network inference submitted through the DREAM5 challenge. It demonstrates that integration…”
Get full text

Chapter 2 - Integrated Inference and Analysis of Regulatory Networks from Multi-Level Measurements by Poultney, Christopher S, Greenfield, Alex, Bonneau, Richard

“…Regulatory and signaling networks coordinate the enormously complex interactions and processes that control cellular processes (such as metabolism and cell…”
Get full text

Structure prediction and visualization in molecular biology by Poultney, Christopher S

“…The tools of computer science can be a tremendous help to the working biologist. Two broad areas where this is particularly true are visualization and…”
Get full text

Computational Methods in Cell Biology by Asthagiri, Anand R, Arkin, Adam

“…Computational methods are playing an ever increasing role in cell biology.  This volume of Methods in Cell Biology focuses on Computational Methods in Cell…”
Get full text