Search Results - "Poulsen, J H"

Bicarbonate Conductance and pH Regulatory Capability of Cystic Fibrosis Transmembrane Conductance Regulator by Poulsen, Jorgen Hedemark, Fischer, Horst, Illek, Beate, Machen, Terry E.

“…The cystic fibrosis transmembrane conductance regulator (CFTR) is an epithelial Cl-channel regulated by protein kinase A. The most common mutation in cystic…”
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Combined alcian blue and silver staining of subnanogram quantities of proteoglycans and glycosaminoglycans in sodium dodecyl sulfate-polyacrylamide gels by Møller, H J, Heinegård, D, Poulsen, J H

“…Proteoglycans stain weakly in polyacrylamide gels by traditional protein stains such as coomassie brilliant blue or silver. In the present work preparations of…”
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The effects of low-dose methotrexate on thymidylate synthetase activity in human peripheral blood mononuclear cells by HORNUNG, N, STENGAARD-PEDERSEN, K, EHRNROOTH, E, ELLINGSEN, T, POULSEN, J. H

“…Methotrexate (MTX) in low doses is widely used in the treatment of rheumatoid arthritis (RA) and it is not known whether its effects are due to…”
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Comparison of the pharmacokinetics of tacrolimus and cyclosporine at equivalent molecular doses by Karamperis, N, Povlsen, J.V, Højskov, C, Poulsen, J.H, Pedersen, A.R, Jørgensen, K.A

“…Even though calcineurin inhibitors, namely Tacrolimus (FK) and Cyclosporine (CsA) share similar physicochemical properties and a common mechanism of action,…”
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Citalopram: interaction studies with levomepromazine, imipramine, and lithium by Gram, L F, Hansen, M G, Sindrup, S H, Brøsen, K, Poulsen, J H, Aaes-Jørgensen, T, Overø, K F

“…The pharmacokinetic interactions between the selective serotonin reuptake inhibitor citalopram, given as an oral dose of 40 mg/day for 10 days, and (1)…”
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Optimal time for determination of blood tacrolimus level by Jørgensen, K.A., Povlsen, J.V., Poulsen, J.H.

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Evaluation of clinical assays for measuring high-dose methotrexate in plasma by ALBERTIONI, F, RASK, C, EKSBORG, S, POULSEN, J. H, PETTERSSON, B, BECK, O, SCHROEDER, H, PETERSON, C

“…Four routine assays commonly used for monitoring plasma methotrexate (MTX) during high-dose therapy were validated by HPLC as the comparison method. MTX and…”
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Two-hour blood tacrolimus levels are not superior to trough levels as estimates of the area under the curve in tacrolimus-treated renal transplant patients by Jørgensen, K.A, Povlsen, J.V, Madsen, S, Madsen, M, Hansen, H.E, Pedersen, A.R, Heinsvig, E.M, Poulsen, J.H

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Differential effect of methotrexate on the increased CCR2 density on circulating CD4 T lymphocytes and monocytes in active chronic rheumatoid arthritis, with a down regulation only on monocytes in responders by Ellingsen, T, Hornung, N, Møller, B K, Poulsen, J H, Stengaard-Pedersen, K

“…Objectives: To evaluate the effect of orally administered methotrexate (MTX) on the density of CC chemokine receptor 2 (CCR2) and CXC chemokine receptor 3…”
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Improved Method for Silver Staining of Glycoproteins in Thin Sodium Dodecyl Sulfate Polyacrylamide Gels by Moller, H.J., Poulsen, J.H.

“…A method for detection of glycoproteins in thin sodium dodecyl sulfate polyacrylamide gels was developed by a combination of (i) initial periodic acid…”
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ELISA for the core protein of the cartilage large aggregating proteoglycan, aggrecan: comparison with the concentrations of immunogenic keratan sulphate in synovial fluid, serum and urine by Møller, H J, Larsen, F S, Ingemann-Hansen, T, Poulsen, J H

“…Immunological assays for fragments of the cartilage large aggregating proteoglycan, aggrecan, have been widely used to monitor cartilage turnover. These assays…”
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A new quantitative RT–PCR assay for thymidylate synthase mRNA in blood leukocytes applied to cancer patients and healthy controls by Ehrnrooth, Eva, Sørensen, Boe S., Meldgaard, Peter, Hornung, Nete, Hjelm Poulsen, Jørgen, von der Maase, Hans

“…Thymidylate synthase (TS) is the target enzyme for 5-fluorouracil (5-FU). TS mRNA and protein levels in colorectal tumours are among the most important…”
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Changes in thymidylate synthase mRNA in blood leukocytes from patients with colorectal cancer after bolus administration of 5-fluorouracil by Ehrnrooth, E, Sørensen, B, Poulsen, J H, Sørensen, B S, von der Maase, H

“…5-fluorouracil (5-FU) is considered the standard antineoplastic drug of choice for metastatic colorectal cancer. It has been suggested that 5-FU administered…”
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The ability of hypoxia to modify the gene expression of thymidylate synthase in tumour cells in vivo by EHRNROOTH, H. VON DER MAASE, B. S. SORENSEN, J. HJELM POULSEN, M. R. HORSMAN, E.

“…Purpose: Hypoxic cells in tumours are resistant to 5-fluorouracil (5-FU). This in vivo study investigated the ability of hypoxia to regulate the gene…”
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The effect of iron overload and iron reductive treatment on the serum concentration of carbohydrate-deficient transferrin by Jensen, P D, Peterslund, N A, Poulsen, J H, Jensen, F T, Christensen, T, Ellegaard, J

“…The concentration of carbohydrate-deficient transferrin in serum (CDT) has been used as a reliable indicator of recent alcohol consumption. We have…”
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Demonstration of immunogenic keratan sulphate in commercial chondroitin 6-sulphate from shark cartilage. Implications for ELISA assays by Møller, Holger J., Møller-Pedersen, Torben, Damsgaard, Tine E., Poulsen, Jørgen H.

“…The prototype monoclonal keratan sulphate (KS) antibody 5D4 that is widely used for detection of KS in tissues and biological fluids reacts strongly with…”
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Lacrimal gland electrolyte and water secretion in the rabbit: localization and role of (Na+ + K+)-activated ATPase by Dartt, D A, Møller, M, Poulsen, J H

“…1. The rate of acetylcholine (ACh)-induced fluid secretion was measured from the main secretory duct of rabbit lacrimal glands perfused in vivo with Krebs…”
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Effect of flunarizine and calcium on serotonin uptake in human and rat blood platelets and rat synaptosomes by Jensen, P N, Smith, D F, Poulsen, J H, Møller, H J, Rosenberg, R

“…Calcium and the calcium overload blocker flunarizine exert profound effects on mood. We therefore studied the effect of calcium and flunarizine on serotonin…”
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Effects of Ca2+ and furosemide on Cl- transport and O2 uptake in rat parotid acini by Nauntofte, B, Poulsen, J H

“…Stimulation-induced changes in Cl- content and O2 consumption of collagenase-isolated rat parotid acini were measured. In less than 10 s, carbachol caused a…”
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Comparison of calcium carbonate and aluminium hydroxide as phosphate binders on biochemical bone markers, PTH(1-84), and bone mineral content in dialysis patients by Jespersen, B, Jensen, J D, Nielsen, H K, Lauridsen, I N, Andersen, M J, Poulsen, J H, Gammelgaard, B, Pedersen, E B

“…Bone mineral content, estimated by single-photon absorptiometry of the forearm, serum values of intact parathyroid hormone (PTH(1-84], osteocalcin, alkaline…”
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