Search Results - "Poulakis, K."

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  1. 1

    Multi-cohort and longitudinal Bayesian clustering study of stage and subtype in Alzheimer’s disease by Poulakis, Konstantinos, Pereira, Joana B., Muehlboeck, J.-Sebastian, Wahlund, Lars-Olof, Smedby, Örjan, Volpe, Giovanni, Masters, Colin L., Ames, David, Niimi, Yoshiki, Iwatsubo, Takeshi, Ferreira, Daniel, Westman, Eric

    Published in Nature communications (05-08-2022)
    “…Understanding Alzheimer’s disease (AD) heterogeneity is important for understanding the underlying pathophysiological mechanisms of AD. However, AD atrophy…”
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    Journal Article
  2. 2

    Frontoparietal atrophy trajectories in cognitively unimpaired elderly individuals using longitudinal Bayesian clustering by Lorenzon, G., Poulakis, K., Mohanty, R., Kivipelto, M., Eriksdotter, M., Ferreira, D., Westman, E.

    Published in Computers in biology and medicine (01-11-2024)
    “…Frontal and/or parietal atrophy has been reported during aging. To disentangle the heterogeneity previously observed, this study aimed to uncover different…”
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  3. 3

    Brain myoinositol as a potential marker of amyloid-related pathology: A longitudinal study by Voevodskaya, Olga, Poulakis, Konstantinos, Sundgren, Pia, van Westen, Danielle, Palmqvist, Sebastian, Wahlund, Lars-Olof, Stomrud, Erik, Hansson, Oskar, Westman, Eric

    Published in Neurology (29-01-2019)
    “…OBJECTIVETo investigate the association between longitudinal changes in proton magnetic resonance spectroscopy (MRS) metabolites and amyloid pathology in…”
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  4. 4

    Unraveling Parkinson's disease heterogeneity using subtypes based on multimodal data by Albrecht, Franziska, Poulakis, Konstantinos, Freidle, Malin, Johansson, Hanna, Ekman, Urban, Volpe, Giovanni, Westman, Eric, Pereira, Joana B., Franzén, Erika

    Published in Parkinsonism & related disorders (01-09-2022)
    “…Parkinson's disease (PD) is a clinically and neuroanatomically heterogeneous neurodegenerative disease characterized by different subtypes. To this date, no…”
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    Clustering and disease subtyping in Neuroscience, toward better methodological adaptations by Poulakis, Konstantinos, Westman, Eric

    “…[...]in research the differences between the two are often overlooked. [...]we want to highlight the applications and challenges of clustering, where…”
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  7. 7

    [18F]THK5317 imaging as a tool for predicting prospective cognitive decline in Alzheimer’s disease by Chiotis, Konstantinos, Savitcheva, Irina, Poulakis, Konstantinos, Saint-Aubert, Laure, Wall, Anders, Antoni, Gunnar, Nordberg, Agneta

    Published in Molecular psychiatry (01-10-2021)
    “…Cross-sectional studies have indicated potential for positron emission tomography (PET) in imaging tau pathology in Alzheimer’s disease (AD); however, its…”
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  8. 8

    Investigating underlying brain structures and influence of mild and subjective cognitive impairment on dual-task performance in people with Parkinson’s disease by Albrecht, Franziska, Johansson, Hanna, Ekman, Urban, Poulakis, Konstantinos, Bezuidenhout, Lucian, Pereira, Joana B., Franzén, Erika

    Published in Scientific reports (25-04-2024)
    “…Cognitive impairment can affect dual-task abilities in Parkinson’s disease (PD), but it remains unclear whether this is also driven by gray matter alterations…”
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    Demographic and Clinical Characteristics of Individuals with Mild Cognitive Impairment Related to Grade of Alcohol Consumption by Tsevis, Theofanis, Westman, Eric, Poulakis, Konstantinos, Lindberg, Olof, Badji, Atef, Religa, Dorota, Wahlund, Lars-Olof

    Published in Dementia and geriatric cognitive disorders (01-01-2022)
    “…While alcohol overconsumption is regarded as a risk factor for Alzheimer's disease, the specific relationship between alcohol consumption and cognitive…”
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    Fully bayesian longitudinal unsupervised learning for the assessment and visualization of AD heterogeneity and progression by Poulakis, Konstantinos, Ferreira, Daniel, Pereira, Joana B, Smedby, Örjan, Vemuri, Prashanthi, Westman, Eric

    Published in Aging (Albany, NY.) (2020)
    “…Tau pathology and brain atrophy are the closest correlate of cognitive decline in Alzheimer's disease (AD). Understanding heterogeneity and longitudinal…”
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  13. 13

    Exploring Responsiveness to Highly Challenging Balance and Gait Training in Parkinson's Disease by Albrecht, Franziska, Johansson, Hanna, Poulakis, Konstantinos, Westman, Eric, Hagströmer, Maria, Franzén, Erika

    “…Background Exercise potentially improves gait, balance, and habitual physical activity in Parkinson's disease (PD). However, given the heterogeneous nature of…”
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  14. 14

    Heterogeneous patterns of brain atrophy in Alzheimer's disease by Poulakis, Konstantinos, Pereira, Joana B., Mecocci, Patrizia, Vellas, Bruno, Tsolaki, Magda, Kłoszewska, Iwona, Soininen, Hilkka, Lovestone, Simon, Simmons, Andrew, Wahlund, Lars-Olof, Westman, Eric

    Published in Neurobiology of aging (01-05-2018)
    “…There is increasing evidence showing that brain atrophy varies between patients with Alzheimer's disease (AD), suggesting that different anatomical patterns…”
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    Comparison of subtyping methods for neuroimaging studies in Alzheimer’s disease: a call for harmonization by Mohanty, Rosaleena, Mårtensson, Gustav, Poulakis, Konstantinos, Muehlboeck, J-Sebastian, Rodriguez-Vieitez, Elena, Chiotis, Konstantinos, Grothe, Michel J, Nordberg, Agneta, Ferreira, Daniel, Westman, Eric

    Published in Brain communications (01-01-2020)
    “…Abstract Biological subtypes in Alzheimer’s disease, originally identified on neuropathological data, have been translated to in vivo biomarkers such as…”
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    Longitudinal deterioration of white-matter integrity: heterogeneity in the ageing population by Poulakis, Konstantinos, Reid, Robert I, Przybelski, Scott A, Knopman, David S, Graff-Radford, Jonathan, Lowe, Val J, Mielke, Michelle M, Machulda, Mary M, Jack, Clifford R, Petersen, Ronald C, Westman, Eric, Vemuri, Prashanthi

    Published in Brain communications (01-01-2021)
    “…Abstract Deterioration in white-matter health plays a role in cognitive ageing. Our goal was to discern heterogeneity of white-matter tract vulnerability in…”
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