Search Results - "Pouladi, Nima"
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Identification of Jak-STAT signaling involvement in sarcoidosis severity via a novel microRNA-regulated peripheral blood mononuclear cell gene signature
Published in Scientific reports (26-06-2017)“…Sarcoidosis is a granulomatous lung disorder of unknown cause. The majority of individuals with sarcoidosis spontaneously achieve full remission (uncomplicated…”
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Novel disease syndromes unveiled by integrative multiscale network analysis of diseases sharing molecular effectors and comorbidities
Published in BMC medical genomics (31-12-2018)“…Forty-two percent of patients experience disease comorbidity, contributing substantially to mortality rates and increased healthcare costs. Yet, the…”
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Progressive multifocal leukoencephalopathy in purine nucleoside phosphorylase deficiency
Published in Brain & development (Tokyo. 1979) (01-03-2007)“…Progressive multifocal leukoencephalopathy is a demyelinating disease caused by JC virus, an opportunistic infection of the central nervous system. Although…”
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Evaluation of liver diseases in Iranian patients with primary antibody deficiencies
Published in Annals of hepatology (01-07-2009)“…Patients with primary antibody deficiency (PAD) can complicate with liver disease. This study was performed in order to study the prevalence and causes of…”
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Rhinovirus Infections in Individuals with Asthma Increase ACE2 Expression and Cytokine Pathways Implicated in COVID-19
Published in American journal of respiratory and critical care medicine (01-09-2020)“…Chang et al discuss their study which tested their hypothesis that rhinovirus infections could increase expression of ACE2 and subsequently activate cytokine…”
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Abstract 2782: MicroRNAs response to concurrent chemoradiotherapy predicts oligo- and polymetastatic progression in patients with Stage IV colorectal adenocarcinoma
Published in Cancer research (Chicago, Ill.) (01-07-2019)“…Colorectal cancer (CRC) is the third most common cancer and an important contributor to cancer mortality and morbidity worldwide. The survival rate (11%) in…”
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Epithelial cell responses to rhinovirus identify an early-life-onset asthma phenotype in adults
Published in Journal of allergy and clinical immunology (01-02-2022)Get full text
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Genotype-Phenotype Correlation in Bruton's Tyrosine Kinase Deficiency
Published in Journal of pediatric hematology/oncology (01-09-2008)Get full text
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‘Single-subject studies’-derived analyses unveil altered biomechanisms between very small cohorts: implications for rare diseases
Published in Bioinformatics (Oxford, England) (01-07-2021)“…Abstract Motivation Identifying altered transcripts between very small human cohorts is particularly challenging and is compounded by the low accrual rate of…”
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Genome-Wide Association Study in African Americans with Acute Respiratory Distress Syndrome Identifies the Selectin P Ligand Gene as a Risk Factor
Published in American journal of respiratory and critical care medicine (01-06-2018)“…Genetic factors are involved in acute respiratory distress syndrome (ARDS) susceptibility. Identification of novel candidate genes associated with increased…”
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Epithelial cell responses to rhinovirus identify an early-life–onset asthma phenotype in adults
Published in Journal of allergy and clinical immunology (01-09-2022)“…The study of pathogenic mechanisms in adult asthma is often marred by a lack of precise information about the natural history of the disease. Children who have…”
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Complex genetics of pulmonary diseases: lessons from genome-wide association studies and next-generation sequencing
Published in Translational research : the journal of laboratory and clinical medicine (01-02-2016)“…The advent of high-throughput technologies has provided exceptional assistance for lung scientists to discover novel genetic variants underlying the…”
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Accelerating precision biology and medicine with computational biology and bioinformatics
Published in Genome Biology (05-09-2014)“…A report on the 22nd Annual International Conference on Intelligent Systems for Molecular Biology, held in Boston, Massachusetts, USA, July 11-15, 2014…”
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Journal Article Conference Proceeding -
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Immunogenetics associated with severe coccidioidomycosis
Published in JCI insight (22-11-2022)“…Disseminated coccidioidomycosis (DCM) is caused by Coccidioides, pathogenic fungi endemic to the southwestern United States and Mexico. Illness occurs in…”
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42. Common Population Variants Cause Susceptibility to Disseminated Coccidioidomycosis
Published in Open forum infectious diseases (31-12-2020)Get full text
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Complex genetics of pulmonary diseases: Lessons from GWAS and next-generation sequencing
Published in Translational research : the journal of laboratory and clinical medicine (07-05-2015)“…The advent of high-throughput technologies has provided exceptional assistance for lung scientists to discover novel genetic variants underlying the…”
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Single subject transcriptome analysis to identify functionally signed gene set or pathway activity
Published in Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing (2018)“…Analysis of single-subject transcriptome response data is an unmet need of precision medicine, made challenging by the high dimension, dynamic nature and…”
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eQTL networks unveil enriched mRNA master integrators downstream of complex disease-associated SNPs
Published in Journal of biomedical informatics (01-12-2015)“…[Display omitted] •We study the downstream transcriptome systems properties of 6432 SNPs of 574 complex diseases.•eQTL network analyses unveil that downstream…”
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Dissecting the Heterogeneity of Breast Tumor Subtypes
Published 01-01-2014“…Breast cancer is the most common cancer in women. The discovery of breast tumor subtypes and the subsequent development of treatments aimed at them has allowed…”
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Dissertation -
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Genotype-phenotype correlation in Bruton's tyrosine kinase deficiency
Published in Journal of pediatric hematology/oncology (01-09-2008)“…Bruton's tyrosine kinase (Btk) belongs to the Tec family of nonreceptor protein tyrosine kinases. Mutations in the BTK gene cause X-linked agammaglobulinemia…”
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