Search Results - "Potts, T. J."

Primary hyperparathyroidism: review and recommendations on evaluation, diagnosis, and management. A Canadian and international consensus by Khan, A. A., Hanley, D. A., Rizzoli, R., Bollerslev, J., Young, J.E.M, Rejnmark, L., Thakker, R., D’Amour, P., Paul, T., Van Uum, S., Shrayyef, M. Zakaria, Goltzman, D., Kaiser, S., Cusano, N. E., Bouillon, R., Mosekilde, L., Kung, A. W., Rao, S. D., Bhadada, S. K., Clarke, B. L., Liu, J., Duh, Q., Lewiecki, E. Michael, Bandeira, F., Eastell, R., Marcocci, C., Silverberg, S. J., Udelsman, R., Davison, K. Shawn, Potts, J. T., Brandi, M. L., Bilezikian, J. P.

“…The purpose of this review is to assess the most recent evidence in the management of primary hyperparathyroidism (PHPT) and provide updated recommendations…”
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Expression Cloning of a Common Receptor for Parathyroid Hormone and Parathyroid Hormone-Related Peptide from Rat Osteoblast-Like Cells: A Single Receptor Stimulates Intracellular Accumulation of Both cAMP and Inositol Trisphosphates and Increases Intracellular Free Calcium by Abou-Samra, Abdul-Badi, Juppner, Harald, Force, Thomas, Freeman, Mason W., Kong, Xiang-Fu, Schipani, Ernestina, Urena, Pablo, Richards, Jennifer, Bonventre, Joseph V., Potts, John T., Kronenberg, Henry M., Segre, Gino V.

“…Parathyroid hormone (PTH), a major regulator of mineral ion metabolism, and PTH-related peptide (PTHrP), which causes hypercalcemia in some cancer patients,…”
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Contraction-sensitive skeletal muscle afferents inhibit arterial baroreceptor signalling in the nucleus of the solitary tract: role of intrinsic GABA interneurons by Potts, J.T., Paton, J.F.R., Mitchell, J.H., Garry, M.G., Kline, G., Anguelov, P.T., Lee, S.M.

“…Arterial baroreceptor and skeletal muscle receptor afferents relay sensory information to the nucleus of the solitary tract (NTS) during exercise. Previous…”
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Carotid baroreflex responsiveness during dynamic exercise in humans by Potts, J T, Shi, X R, Raven, P B

“…We utilized 5-s changes of neck pressure and neck suction (from 40 to -80 Torr) to alter carotid sinus transmural pressure in seven men with peak oxygen uptake…”
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Targeted deletion of neurokinin-1 receptor expressing nucleus tractus solitarii neurons precludes somatosensory depression of arterial baroreceptor–heart rate reflex by Potts, J.T, Fong, A.Y, Anguelov, P.I, Lee, S, McGovern, D, Grias, I

“…Abstract Neurokinin-1 receptor (NK1-R) expressing neurons are densely distributed throughout the nucleus tractus solitarii (NTS). However, their fundamental…”
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Amino-Terminal Modifications of Human Parathyroid Hormone (PTH) Selectively Alter Phospholipase C Signaling via the Type 1 PTH Receptor:  Implications for Design of Signal-Specific PTH Ligands by Takasu, Hisashi, Gardella, Thomas J, Luck, Michael D, Potts, John T, Bringhurst, F. Richard

“…Parathyroid hormone (PTH) and PTH-related peptide (PTHrP) activate the PTH/PTHrP receptor to trigger parallel increases in adenylyl cyclase (AC) and…”
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A G Protein-Linked Receptor for Parathyroid Hormone and Parathyroid Hormone-Related Peptide by Jüppner, Harald, Abou-Samra, Abdul-Badi, Freeman, Mason, Kong, Xiang F., Schipani, Ernestina, Richards, Jennifer, Kolakowski, Lee F., Hock, Janet, Potts, John T., Kronenberg, Henry M., Segre, Gino V.

“…The complementary DNA encoding a 585-amino acid parathyroid hormone-parathyroid hormone-related peptide (PTH-PTHrP) receptor with seven potential…”
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Exercise and sensory integration. Role of the nucleus tractus solitarius by Potts, J T

“…Since NTS neurons receive synaptic input from many sensory modalities, it is crucial to understand the neuronal mechanisms involved in synaptic processing. We…”
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Discharge patterns of somatosensitive neurons in the nucleus tractus solitarius of the cat by Potts, J.T., Waldrop, T.G.

“…Encoding of sensory information by nucleus of the solitary tract (NTS) neurons is incompletely understood. Using extracellular single-unit recording in…”
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Cloned, stably expressed parathyroid hormone (PTH)/PTH-related peptide receptors activate multiple messenger signals and biological responses in LLC-PK1 kidney cells by Bringhurst, F R, Juppner, H, Guo, J, Urena, P, Potts, Jr, J T, Kronenberg, H M, Abou-Samra, A B, Segre, G V

“…PTH elicits multiple second messenger signals in target cells. This signaling diversity may reflect coupling of a single species of PTH receptors to multiple…”
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Minimization of parathyroid hormone. Novel amino-terminal parathyroid hormone fragments with enhanced potency in activating the type-1 parathyroid hormone receptor by Shimizu, M, Potts, Jr, J T, Gardella, T J

“…The amino-terminal and carboxyl-terminal portions of the 1-34 fragment of parathyroid hormone (PTH) contain the major determinants of receptor activation and…”
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Mutations in the Second Cytoplasmic Loop of the Rat Parathyroid Hormone (PTH)/PTH-related Protein Receptor Result in Selective Loss of PTH-stimulated Phospholipase C Activity by Iida-Klein, Akiko, Guo, Jun, Takemura, Masahiko, Drake, Matthew T., Potts, John T., Abou-Samra, Abdul, Bringhurst, F. Richard, Segre, Gino V.

“…To define the structural requirements of the parathyroid hormone (PTH)/PTH-related protein (PTHrP) receptor necessary for activation of phospholipase C (PLC),…”
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The extracellular amino-terminal region of the parathyroid hormone (PTH)/PTH-related peptide receptor determines the binding affinity for carboxyl-terminal fragments of PTH-(1-34) by Jüppner, H, Schipani, E, Bringhurst, F R, McClure, I, Keutmann, H T, Potts, Jr, J T, Kronenberg, H M, Abou-Samra, A B, Segre, G V, Gardella, T J

“…The recombinant human PTH/PTH-related peptide (PTHrP) receptor, when transiently expressed in COS-7 cells, binds [Nle8,18,Tyr34] bovine PTH-(7-34)amide…”
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Identical complementary deoxyribonucleic acids encode a human renal and bone parathyroid hormone (PTH)/PTH-related peptide receptor by Schipani, E, Karga, H, Karaplis, A C, Potts, Jr, J T, Kronenberg, H M, Segre, G V, Abou-Samra, A B, Jüppner, H

“…Identical complementary DNAs (cDNAs) that encode a 593-amino acid human PTH (PTH)/PTH-related peptide (PTHrP) receptor were isolated by hybridization…”
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Parathyroid hormone (PTH)/PTH-related peptide receptor messenger ribonucleic acids are widely distributed in rat tissues by Ureña, P, Kong, X F, Abou-Samra, A B, Jüppner, H, Kronenberg, H M, Potts, Jr, J T, Segre, G V

“…PTH/PTH-related peptide (PTHrP) receptor mRNAs are widely distributed in rat tissues. PTH and PTHrP, a peptide responsible for hypercalcemia associated with…”
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Reflex cardiovascular responses evoked by selective activation of skeletal muscle ergoreceptors by Leshnower, B. G, Potts, J. T, Garry, M. G, Mitchell, J. H

“…1  Departments of Internal Medicine and Physiology and 2  Anesthesiology and Pain Management, Harry S. Moss Heart Center, University of Texas Southwestern…”
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Naturalistic activation of barosensitive afferents release substance P in the nucleus tractus solitarius of the cat by Potts, J.T., Fuchs, I.E.

“…The role for substance P (SP) in baroreceptor transmission in the nucleus tractus solitarius (NTS) remains an area of active research. The purpose of the…”
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Highly sensitive two-site immunoradiometric assay of parathyrin, and its clinical utility in evaluating patients with hypercalcemia by Nussbaum, S R, Zahradnik, R J, Lavigne, J R, Brennan, G L, Nozawa-Ung, K, Kim, L Y, Keutmann, H T, Wang, C A, Potts, Jr, J T, Segre, G V

“…We have developed a highly sensitive, two-site immunoradiometric assay (IRMA) for human parathyrin (PTH) that is specific for the intact, secreted,…”
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The parathyroid hormone-like peptide associated with humoral hypercalcemia of malignancy and parathyroid hormone bind to the same receptor on the plasma membrane of ROS 17/2.8 cells by Jüppner, H, Abou-Samra, A B, Uneno, S, Gu, W X, Potts, J T, Segre, G V

“…[Tyr36]human adenylate cyclase stimulating peptide (1-36)-NH2, an amino-terminal analog of a tumor peptide which is associated with hypercalcemia of…”
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c-Fos expression in the medulla induced by static muscle contraction in cats by Li, J, Hand, G A, Potts, J T, Wilson, L B, Mitchell, J H

“…In this study, we examined Fos-like immunoreactivity (FLI) in the medulla after static muscle contraction induced by stimulation of L7 and S1 ventral roots of…”
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