Search Results - "Potts, Kyle G."

VSV∆M51 drives CD8+ T cell-mediated tumour regression through infection of both cancer and non-cancer cells by Rajwani, Jahanara, Vishnevskiy, Daniil, Turk, Madison, Naumenko, Victor, Gafuik, Chris, Kim, Dae-Sun, Mah, Laura K., Snelling, Shannon, Gonzales, Gerone A., Xue, Jingna, Chanda, Ayan, Potts, Kyle G., Todesco, Hayley M., Lau, Keith C. K., Hildebrand, Karys M., Chan, Jennifer A., Liao, Shan, Monument, Michael J., Hyrcza, Martin, Bose, Pinaki, Jenne, Craig N., Canton, Johnathan, Zemp, Franz J., Mahoney, Douglas J.

“…Oncolytic viruses (OV) are designed to selectively infect and kill cancer cells, while simultaneously eliciting antitumour immunity. The mechanism is expected…”
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Procaspase-Activating Compound-1 Synergizes with TRAIL to Induce Apoptosis in Established Granulosa Cell Tumor Cell Line (KGN) and Explanted Patient Granulosa Cell Tumor Cells In Vitro by Crosley, Powel, Farkkila, Anniina, Jenner, Adrianne L, Burlot, Chloé, Cardinal, Olivia, Potts, Kyle G, Agopsowicz, Kate, Pihlajoki, Marjut, Heikinheimo, Markku, Craig, Morgan, Fu, Yangxin, Hitt, Mary M

“…Granulosa cell tumors (GCT) constitute only ~5% of ovarian neoplasms yet have significant consequences, as up to 80% of women with recurrent GCT will die of…”
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Deletion of F4L (ribonucleotide reductase) in vaccinia virus produces a selective oncolytic virus and promotes anti‐tumor immunity with superior safety in bladder cancer models by Potts, Kyle G, Irwin, Chad R, Favis, Nicole A, Pink, Desmond B, Vincent, Krista M, Lewis, John D, Moore, Ronald B, Hitt, Mary M, Evans, David H

“…Bladder cancer has a recurrence rate of up to 80% and many patients require multiple treatments that often fail, eventually leading to disease progression. In…”
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High-titer manufacturing of SARS-CoV-2 Spike-pseudotyped VSV in stirred-tank bioreactors by Todesco, Hayley M., Gafuik, Chris, John, Cini M., Roberts, Erin L., Borys, Breanna S., Pawluk, Alexis, Kallos, Michael S., Potts, Kyle G., Mahoney, Douglas J.

“…The severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) pandemic highlighted the importance of vaccine innovation in public health. Hundreds of…”
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Oncolytic Viruses in the Treatment of Bladder Cancer by Potts, Kyle G., Moore, Ronald B., Hitt, Mary M.

“…Bladder carcinoma is the second most common malignancy of the urinary tract. Up to 85% of patients with bladder cancer are diagnosed with a tumor that is…”
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Novel colchicine derivative CR42-24 demonstrates potent anti-tumor activity in urothelial carcinoma by Bell, Clayton J., Potts, Kyle G., Hitt, Mary M., Pink, Desmond, Tuszynski, Jack A., Lewis, John D.

“…Bladder cancers, and specifically urothelial carcinoma, have few effective treatment options, and tumors typically develop resistance against standard of care…”
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A B1a-natural IgG-neutrophil axis is impaired in viral- and steroid-associated aspergillosis by Sarden, Nicole, Sinha, Sarthak, Potts, Kyle G, Pernet, Erwan, Hiroki, Carlos H, Hassanabad, Mortaza F, Nguyen, Angela P, Lou, Yuefei, Farias, Raquel, Winston, Brent W, Bromley, Amy, Snarr, Brendan D, Zucoloto, Amanda Z, Andonegui, Graciela, Muruve, Daniel A, McDonald, Braedon, Sheppard, Donald C, Mahoney, Douglas J, Divangahi, Maziar, Rosin, Nicole, Biernaskie, Jeff, Yipp, Bryan G

“…The lung naturally resists ( ) in healthy individuals, but multiple conditions can disrupt this resistance, leading to lethal invasive infections. Core…”
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Stroke-associated intergenic variants modulate a human FOXF2 transcriptional enhancer by Ryu, Jae-Ryeon, Ahuja, Suchit, Arnold, Corey R, Potts, Kyle G, Mishra, Aniket, Yang, Qiong, Sargurupremraj, Muralidharan, Mahoney, Douglas J, Seshadri, Sudha, Debette, Stéphanie, Childs, Sarah J

“…SNPs associated with human stroke risk have been identified in the intergenic region between Forkhead family transcription factors and , but we lack a…”
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Identification of FDA-approved bifonazole as a SARS-CoV-2 blocking agent following a bioreporter drug screen by Taha, Zaid, Arulanandam, Rozanne, Maznyi, Glib, Godbout, Elena, Carter-Timofte, Madalina E., Kurmasheva, Naziia, Reinert, Line S., Chen, Andrew, Crupi, Mathieu J.F., Boulton, Stephen, Laroche, Geneviève, Phan, Alexandra, Rezaei, Reza, Alluqmani, Nouf, Jirovec, Anna, Acal, Alexandra, Fekete, Emily E.F., Singaravelu, Ragunath, Petryk, Julia, Idorn, Manja, Potts, Kyle G., Todesco, Hayley, John, Cini, Mahoney, Douglas J., Ilkow, Carolina S., Giguère, Patrick, Alain, Tommy, Côté, Marceline, Paludan, Søren R., Olagnier, David, Bell, John C., Azad, Taha, Diallo, Jean-Simon

“…We established a split nanoluciferase complementation assay to rapidly screen for inhibitors that interfere with binding of the receptor binding domain (RBD)…”
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Radiation-Induced Cellular Senescence Reduces Susceptibility of Glioblastoma Cells to Oncolytic Vaccinia Virus by Storozynsky, Quinn T, Han, Xuefei, Komant, Shae, Agopsowicz, Kate C, Potts, Kyle G, Gamper, Armin M, Godbout, Roseline, Evans, David H, Hitt, Mary M

“…Glioblastoma (GBM) is a malignant brain cancer refractory to the current standard of care, prompting an extensive search for novel strategies to improve…”
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Assessment of Specificity of an Adenovirus Targeted to HER3/4 by MacLeod, Sheena H, Potts, Kyle G, Chaurasiya, Shyambabu, Hitt, Mary M

“…Gene therapy with viral vectors, such as adenovirus (Ad), targeted to the human epidermal growth factor receptors 3 and 4 (HER3/4) are potentially useful for…”
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Oncolytic Viruses in the Treatment of Bladder Cancer by Kyle G. Potts, Mary M. Hitt, Ronald B. Moore

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